OR5P2 Olfactory Receptor
| Gene Symbol | OR5P21 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | P |
| Pseudogene | No |
| CORP pseudogene probability score | 0.34 (functional) |
| Aliases | OR11-93, JCG3, HsOR11.5.4P, ORL3373 |
| External Ids | HGNC: 14783 GeneBank: AB065767, AF173006, BK004322, NM_153444 ORDB: ORL3373 |
| Build #39 labels | OR5P2 |
| Chromosomal location | 11:7,795,977-7,796,942 (-) |
| Cluster | 11@8 |
| Synteny | CLIC#25 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5P3 | 63.96% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5P6 | 78% | 312 |
| Mouse | Or5p76 | 79% | 314 |
| Rat | Or5p76b | 78% | 314 |
| Cow | OR5P76B | 79% | 311 |
| Orang | OR5P3 | 63% | 311 |
| Horse | OR5P2B | 80% | 314 |
| Chimp | OR5P3 | 63% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AF220494 |
| GNF Atlas2 | gnf1h05414_at |
Sequence information
| Nucleotide sequence |
ATGAATTCCCTGAAGGACGGGAATCACACCGCTCTGACGGGGTTCATCCTATTGGGCTTA ACAGATGATCCAATCCTTCGAGTCATCCTCTTCATGATCATCCTATCTGGTAATCTCAGC ATAATTATTCTTATCAGAATTTCTTCTCAGCTCCATCATCCTATGTATTTCTTTCTGAGC CACTTGGCTTTTGCTGACATGGCCTATTCATCTTCTGTCACACCCAACATGCTTGTAAAC TTCCTGGTGGAGAGAAATACAGTCTCCTACCTTGGATGTGCCATCCAGCTTGGTTCAGCG GCTTTCTTTGCAACAGTCGAATGCGTCCTTCTGGCTGCCATGGCCTATGACCGCTTTGTG GCAATTTGCAGTCCACTGCTTTATTCAACCAAAATGTCCACACAAGTCAGTGTCCAGCTA CTCTTAGTAGTTTACATAGCTGGTTTTCTCATTGCTGTCTCCTATACTACTTCCTTCTAT TTTTTACTCTTCTGTGGACCAAATCAAGTCAATCATTTTTTCTGTGATTTCGCTCCCTTA CTTGAACTCTCCTGTTCTGATATCAGTGTCTCCACAGTTGTTCTCTCATTTTCTTCTGGA TCCATCATTGTGGTCACTGTGTGTGTCATAGCCGTCTGCTACATCTATATCCTCATCACC ATCCTGAAGATGCGCTCCACTGAGGGGCACCACAAGGCCTTCTCCACCTGCACTTCCCAC CTCACTGTGGTTACCCTGTTCTATGGGACCATTACCTTCATTTATGTGATGCCCAATTTT AGCTACTCAACTGACCAGAACAAGGTGGTGTCTGTGTTGTACACAGTGGTGATTCCCATG TTGAACCCCCTGATCTACAGCCTCAGGAACAAGGAGATTAAGGGGGCTCTGAAGAGAGAG CTTGTTAGAAAAATACTTTCTCATGATGCTTGTTATTTTAGTAGAACTTCAAATAATGAT ATTACA |
| Conceptual translation |
MNSLKDGNHTALTGFILLGLTDDPILRVILFMIILSGNLSIIILIRISSQLHHPMYFFLS HLAFADMAYSSSVTPNMLVNFLVERNTVSYLGCAIQLGSAAFFATVECVLLAAMAYDRFV AICSPLLYSTKMSTQVSVQLLLVVYIAGFLIAVSYTTSFYFLLFCGPNQVNHFFCDFAPL LELSCSDISVSTVVLSFSSGSIIVVTVCVIAVCYIYILITILKMRSTEGHHKAFSTCTSH LTVVTLFYGTITFIYVMPNFSYSTDQNKVVSVLYTVVIPMLNPLIYSLRNKEIKGALKRE LVRKILSHDACYFSRTSNNDIT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | N/D | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | T/C | T/T | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 7,795,991 | 7,795,991 | NS | T/C | N/D | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,118 | 7,796,118 | SYN | T/C | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,305 | 7,796,305 | NS | C/G | C/S | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,309 | 7,796,309 | NS | C/T | V/I | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,412 | 7,796,412 | SYN | G/A | F/F | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,509 | 7,796,509 | NS | T/C | Y/C | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,604 | 7,796,604 | SYN | G/A | A/A | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,643 | 7,796,643 | SYN | C/T | A/A | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,766 | 7,796,766 | SYN | C/T | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 7,796,840 | 7,796,840 | NS | G/T | L/I | 1000GP (CEU) |
| 11 | 7,796,842 | 7,796,842 | NS | A/G | I/T | 1000GP (CEU) |
| 11 | 7,796,924 | 7,796,924 | NS | C/T | G/R | 1000GP (CEU) |
| 11 | 7,817,538 | 7,817,538 | NS | C/T | D/N | rs7949771 (DbSNP) |
| 11 | 7,817,665 | 7,817,665 | SYN | C/T | T/T | rs72484720 (DbSNP) |
| 11 | 7,817,857 | 7,817,857 | SYN | A/G | A/A | rs1976626 (DbSNP) |
| 11 | 7,817,959 | 7,817,959 | SYN | A/G | F/F | rs73406603 (DbSNP) |
| 11 | 7,818,056 | 7,818,056 | NS | C/T | C/Y | rs73406604 (DbSNP) |
| 11 | 7,818,151 | 7,818,151 | SYN | A/G | A/A | rs73406606 (DbSNP) |
| 11 | 7,818,190 | 7,818,190 | SYN | C/T | A/A | rs73406607 (DbSNP) |
| 11 | 7,818,313 | 7,818,313 | SYN | C/T | L/L | rs73406609 (DbSNP) |
| 11 | 7,818,471 | 7,818,471 | NS | C/T | G/R | rs1482804 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| Deletion | 249 (Hasin) | |||
| 11 | 7,785,603 | 7,838,917 | CopyNumber | Variation_35016 (DGV) |
| 11 | 7,802,490 | 7,828,642 | CopyNumber | Variation_85638 (DGV) |
| 11 | 7,806,326 | 7,852,026 | CopyNumber | Variation_35017 (DGV) |
| 11 | 7,811,220 | 7,836,387 | CopyNumber | Variation_22901 (DGV) |
| 11 | 7,812,858 | 7,832,650 | CopyNumber | Variation_65859 (DGV) |
| 11 | 7,813,040 | 7,841,583 | CopyNumber | Variation_38039 (DGV) |
| 11 | 7,813,081 | 7,830,280 | CopyNumber | Variation_75537 (DGV), Variation_85640 (DGV) |
| 11 | 7,813,400 | 7,830,036 | CopyNumber | Variation_37481 (DGV) |
| 11 | 7,813,900 | 7,820,452 | CopyNumber | Variation_85641 (DGV) |
| 11 | 7,815,524 | 7,818,589 | Deletion | #20 (Waszak) |
| 11 | 7,816,357 | 7,827,823 | CopyNumber | Variation_85639 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| N318D | C213S | V212I | Y145C | R118H | G7R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | N | C | V | Y | R | G | 64.44 | 0.283 |
| 2 | D | S | I | C | R | G | 26.04 | 0.118 |
| 3 | N | C | V | Y | R | R | 6.84 | 0.283 |
| 4 | N | C | V | Y | H | G | 0.84 | 0.875 |
| 5 | D | C | V | C | R | G | 0.61 | 0.283 |
| 6 | D | C | V | Y | R | G | 0.38 | 0.283 |
| 7 | N | C | V | Y | H | R | 0.38 | 0.875 |
| 8 | N | S | I | C | R | G | 0.15 | 0.118 |
| 9 | N | C | I | Y | R | G | 0.15 | 0.283 |
| 10 | D | S | I | C | R | R | 0.08 | 0.118 |
| 11 | N | S | I | Y | R | G | 0.08 | 0.118 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5P2.aApr07-unspliced | main_exon | 3UTR | chr11 | 7,795,905 | 7,795,977 | - |
| CDS | chr11 | 7,795,977 | 7,796,942 | - | ||
| 5UTR | chr11 | 7,796,942 | 7,796,973 | - | ||