OR5R1 Olfactory Receptor
| Gene Symbol | OR5R11 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | R |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR11-185, HsOR11.11.67 |
| External Ids | HGNC: 14841 GeneBank: AB065504, BK004514, NM_001004744 |
| Build #39 labels | OR5R1P |
| Chromosomal location | 11:56,417,261-56,418,232 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (rs7111634 and rs6591324) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8U1 | 68.2% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h05459_at |
Sequence information
| Nucleotide sequence |
ATGGCTGAAGTTAATATCATTTATGTCACTGTATTCATTCTGAAAGGAATTACCAACCGG CCAGAGCTTCAGGCCCCGTGCTTTGGGGTGTTTTTAGTTATCTATCTGGTCACAGTGCTG GGCAATCTTGGGTTGATTACTTTAATCAAGATTGATACTCGACTCCACACACCTATGTAC TATTTCCTCAGCCACCTGGCCTTTGTTGACCTTTGTTACTCCTCTGCTATTACACCGAAG ATGATGGTGAATTTTGTTGTGGAACGCAACACCATTCCTTTCCATGCTTGTGCAACCCAA CTGGGTTGTTTTCTCACCTTCATGATCACTGAGTGTTTCCTTCTAGCCTCCATGGCCTAC GATTGCTATGTCGCCATCTGTAGTCCCCTGCATTATTCAACACTGATGTCAAGAAGAGTC TGCATTCAACTGGTGGCAGTTCCATATATATACAGCTTCCTGGTTGCCCTCTTCCACACC GTTATCACTTTCCGTCTGACTTACTGTGGCCCAAACTTAATTAACCATTTCTATTGTGAT GACCTCCCCTTCTTAGCTCTGTCCTGCTCAGACACACACATGAAGGAAATTCTGATATTT GCCTTTGCTGGCTTTGATATGATCTCTTCCTCTTCCATTGTCCTCACCTCCTACATCTTT ATTATTGCCGCTATCCTAAGGATCCGCTCTACTCAGGGGCAACACAAAGCCATTTCCACC TGTGGCTCCCATATGGTGACTGTCACTATTTTCTATGGCACACTGATCTTTATGTACCTA CAGCCCAAATCAAATCACTCCTTGGACACAGACAAGATGGCTTCTGTATTTTACACAGTG GTGATCCCCATGTTAAACCCCCTAATCTATAGTCTAAGGAACAAAGAAGTGAAAGATGCC TCAAAGAAAGCCTTGGATAAAGGTTGTGAAAACTTACAGATATTAACATTTTTAAAAATA AGAAAACTTTAT |
| Conceptual translation |
MAEVNIIYVTVFILKGITNRPELQAPCFGVFLVIYLVTVLGNLGLITLIKIDTRLHTPMY YFLSHLAFVDLCYSSAITPKMMVNFVVERNTIPFHACATQLGCFLTFMITECFLLASMAY DCYVAICSPLHYSTLMSRRVCIQLVAVPYIYSFLVALFHTVITFRLTYCGPNLINHFYCD DLPFLALSCSDTHMKEILIFAFAGFDMISSSSIVLTSYIFIIAAILRIRSTQGQHKAIST CGSHMVTVTIFYGTLIFMYLQPKSNHSLDTDKMASVFYTVVIPMLNPLIYSLRNKEVKDA SKKALDKGCENLQILTFLKIRKLY Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | A/V | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/C | L/L | 1000GP (YRI) |
| 11 | 56,184,888 | 56,184,888 | NS | G/A | A/V | rs998544 (DbSNP) |
| 11 | 56,185,153 | 56,185,153 | NS | C/T | A/T | rs61901985 (DbSNP) |
| 11 | 56,185,159 | 56,185,159 | NS | A/G | F/L | rs7930678 (DbSNP) |
| 11 | 56,185,224 | 56,185,224 | NS | A/G | I/T | rs12785840 (DbSNP) |
| 11 | 56,185,315 | 56,185,315 | NS | A/G | Y/H | rs17150578 (DbSNP) |
| 11 | 56,185,327 | 56,185,327 | NS | C/T | G/S | rs7933772 (DbSNP) |
| 11 | 56,185,345 | 56,185,345 | NS | A/G | C/R | rs6591324 (DbSNP) |
| 11 | 56,185,347 | 56,185,347 | NS | C/T | G/D | rs7111634 (DbSNP) |
| 11 | 56,185,401 | 56,185,401 | NS | C/T | C/Y | rs7123108 (DbSNP) |
| 11 | 56,185,689 | 56,185,689 | NS | A/G | I/T | rs7931261 (DbSNP) |
| 11 | 56,417,412 | 56,417,412 | NS | G/A | A/V | 1000GP (CEU, CHBJPT) |
| 11 | 56,417,548 | 56,417,548 | NS | G/A | R/C | 1000GP (CEU) |
| 11 | 56,417,677 | 56,417,677 | NS | C/T | A/T | 1000GP (CEU) |
| 11 | 56,417,683 | 56,417,683 | NS | A/G | F/L | 1000GP (CEU, CHBJPT) |
| 11 | 56,417,748 | 56,417,748 | NS | A/G | I/T | 1000GP (CEU, CHBJPT) |
| 11 | 56,417,851 | 56,417,851 | NS | T/C | S/G | 1000GP (CEU, CHBJPT) |
| 11 | 56,417,869 | 56,417,869 | NS | A/G | C/R | 1000GP (CEU, CHBJPT) |
| 11 | 56,417,871 | 56,417,871 | NS | T/C | D/G | 1000GP (CEU) |
| 11 | 56,417,925 | 56,417,925 | NS | C/T | C/Y | 1000GP (CEU) |
| 11 | 56,418,213 | 56,418,213 | NS | A/G | I/T | 1000GP (CEU, CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 208 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A274V | R229H | N172K | I162T | Y132H | S128G | Y123C | C122R | D121G | C103Y | P21L | I7T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | V | R | N | I | Y | S | Y | R | D | C | P | I | 40.02 | 0.130 |
| 2 | A | R | N | I | Y | G | Y | R | D | C | P | T | 27.19 | 0.130 |
| 3 | A | R | N | T | Y | S | Y | C | D | C | P | I | 13.98 | 0.727 |
| 4 | A | R | N | I | Y | S | Y | C | D | C | P | I | 9.98 | 0.727 |
| 5 | A | R | N | I | Y | S | Y | R | G | Y | P | I | 4.61 | 1.000 |
| 6 | A | R | N | I | Y | S | Y | R | D | C | P | I | 1.15 | 0.130 |
| 7 | A | R | N | I | Y | S | Y | R | D | C | P | T | 0.92 | 0.130 |
| 8 | A | R | N | I | Y | G | Y | R | D | C | L | T | 0.69 | 0.130 |
| 9 | A | R | N | I | H | G | Y | R | D | C | P | T | 0.54 | 1.000 |
| 10 | V | R | N | I | Y | S | Y | C | D | C | P | I | 0.15 | 0.727 |
| 11 | A | R | N | I | Y | S | Y | R | D | Y | P | I | 0.15 | 0.130 |
| 12 | A | R | K | I | Y | S | C | R | D | C | P | I | 0.15 | 0.089 |
| 13 | V | H | N | I | Y | S | Y | R | D | C | P | I | 0.15 | 0.130 |
| 14 | A | R | N | I | Y | G | Y | R | D | Y | P | T | 0.08 | 0.130 |
| 15 | V | R | N | I | Y | G | Y | R | D | C | P | T | 0.08 | 0.130 |
| 16 | A | R | N | I | H | S | Y | R | D | C | P | T | 0.08 | 1.000 |
| 17 | A | R | N | I | Y | G | Y | R | G | Y | P | T | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5R1.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,417,258 | 56,417,261 | - |
| CDS | chr11 | 56,417,261 | 56,418,232 | - | ||