OR6B3 Olfactory Receptor
| Gene Symbol | OR6B31 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.38 (functional) |
| Aliases | OR2-2, HsOR2.4.2 |
| External Ids | HGNC: 15042 GeneBank: AB065662, AF399471, BK004289, NM_173351 |
| Build #39 labels | OR6B3 |
| Chromosomal location | 2:240,045,080-240,046,072 (-) |
| Cluster | 2@241 |
| Synteny | CLIC#7 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6B2 | 95.44% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6B2 | 83% | 306 |
| Dog | OR6B2C | 82% | 306 |
| Dog | OR6B2D | 81% | 306 |
| Mouse | Or6b3 | 88% | 307 |
| Mouse | Or6b2b | 85% | 307 |
| Mouse | Or6b2 | 85% | 307 |
| Rat | Or6b3 | 87% | 309 |
| Rat | Or6b2b | 85% | 307 |
| Cow | OR6B2 | 85% | 303 |
| Orang | OR6B3P | 93% | 313 |
| Horse | OR6B2 | 86% | 304 |
| Chimp | OR6B17P | 95% | 202 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h10927_at |
Sequence information
| Nucleotide sequence |
ATGAGTGGGGAGAATGTCACCAGGGTCGGCACCTTCATCCTGGTGGGCTTCCCCACGGCC CCAGGGCTGCAGTACCTGCTCTTCCTCCTCTTCCTGCTCACCTACCTCTTTGTCCTGGTG GAGAACCTGGCCATCATCCTCACCGTCTGGAGCAGCACCTCCCTCCACAGGCCCATGTAC TACTTTCTGAGCTCCATGTCTTTCCTAGAGATCTGGTACGTGTCTGACATCACCCCCAAG ATGCTGGAGGGCTTCCTCCTCCAGCAGAAACGCATCTCTTTCGTCGGGTGCATGACGCAG CTCTACTTCTTCAGCTCCCTGGTGTGCACCGAGTGTGTGCTTCTGGCCTCCATGGCCTAC GACCGCTACGTGGCCATCTGCCACCCGCTGCGCTACCACGTCCTTGTGACCCCGGGGCTG TGCCTCCAGCTGGTGGGCTTCTCCTTTGTGAGTGGCTTCACCATCTCCATGATCAAGGTC TGTTTTATCTCCAGCGTCACGTTCTGTGGCTCCAACGTCTTGAACCACTTCTTCTGTGAC ATTTCCCCCATCCTCAAGCTGGCCTGCACGGACTTCTCCACTGCAGAGCTGGTGGATTTC ATTCTGGCCTTCATCATCCTGGTGTTTCCACTCCTGGCCACCATGCTGTCATATGCGCAC ATCACCCTGGCTGTCCTGCGCATCCCCTCGGCCACCGGCTGCTGGAGAGCCTTCTTCACC TGCGCCTCTCACCTCACCGTGGTCACCGTCTTCTATACAGCCTTGCTTTTCATGTATGTC CGGCCCCAGGCCATTGATTCCCGGAGCTCCAACAAGCTCATCTCTGTTTTGTACACAGTT ATCACCCCCATCTTGAACCCCTTGATATACTGCCTGAGGAATAAGGAATTTAAGAATGCC TTGAAAAAAGCCTTCGGCTTGACGAGCTGCGCCGTAGAGGGGAGGCTTTCTAGTCTTCTG GAACTTCATCTCCAAATACACAGCCAGCCTCTC |
| Conceptual translation |
MSGENVTRVGTFILVGFPTAPGLQYLLFLLFLLTYLFVLVENLAIILTVWSSTSLHRPMY YFLSSMSFLEIWYVSDITPKMLEGFLLQQKRISFVGCMTQLYFFSSLVCTECVLLASMAY DRYVAICHPLRYHVLVTPGLCLQLVGFSFVSGFTISMIKVCFISSVTFCGSNVLNHFFCD ISPILKLACTDFSTAELVDFILAFIILVFPLLATMLSYAHITLAVLRIPSATGCWRAFFT CASHLTVVTVFYTALLFMYVRPQAIDSRSSNKLISVLYTVITPILNPLIYCLRNKEFKNA LKKAFGLTSCAVEGRLSSLLELHLQIHSQPL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 2 | 240,985,347 | 240,985,347 | NS | A/G | I/T | rs13030992 (DbSNP) |
| 2 | 240,984,789 | 240,984,789 | NS | C/T | C/Y | rs12465491 (DbSNP) |
| 2 | 240,984,827 | 240,984,827 | SYN | A/G | I/I | rs72993519 (DbSNP) |
| 2 | 240,984,833 | 240,984,833 | SYN | C/G | A/A | rs13389099 (DbSNP) |
| 2 | 240,045,416 | 240,045,416 | SYN | C/G | A/A | 1000GP (CEU, CHBJPT) |
| 2 | 240,045,410 | 240,045,410 | SYN | G/A | I/I | 1000GP (CEU) |
| 2 | 240,045,930 | 240,045,930 | NS | G/A | T/I | 1000GP (CEU) |
| 2 | 100 | -100 | NS | C/T | G/S | 1000GP (YRI) |
| 2 | 100 | -100 | SYN | C/G | A/A | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 2 | 240,911,276 | 241,082,695 | CopyNumber | Variation_0031 (DGV) |
| CopyNumber | 193 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G306S | R261W | C234Y | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | G | R | C | 63.82 | 0.559 |
| 2 | G | R | Y | 35.87 | 0.559 |
| 3 | S | R | C | 0.23 | 0.559 |
| 4 | G | W | Y | 0.08 | 0.559 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6B3.aApr07-unspliced | main_exon | 3UTR | chr2 | 240,045,077 | 240,045,080 | - |
| CDS | chr2 | 240,045,080 | 240,046,072 | - | ||