OR6C2 Olfactory Receptor
Gene Symbol | OR6C21 (View this gene in GeneCards) |
Family | 6 |
Subfamily | C |
Pseudogene | No |
CORP pseudogene probability score | 0.05 (functional) |
Aliases | HSA3, HsOR12.5.19, ORL3812 |
External Ids | HGNC: 15436 GeneBank: AF179766, NM_054105, XM_498546 ORDB: ORL3812 |
Build #39 labels | OR6C2 |
Chromosomal location | 12:55,452,214-55,453,149 (+) |
Cluster | 12@56 |
Synteny | CLIC#31 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR6C68 | 74.68% | 312 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR6C2E | 87% | 312 |
Dog | OR6C2D | 87% | 312 |
Dog | OR6C2IP | 85% | 313 |
Mouse | Or6c2 | 90% | 312 |
Rat | Or6c2 | 89% | 312 |
Rat | Or6c2c | 88% | 291 |
Cow | OR6C2F | 78% | 312 |
Orang | OR6C308 | 79% | 312 |
Horse | OR6C2K | 86% | 312 |
Chimp | OR6C68 | 75% | 312 |
Expression evidences
Source | Accession |
---|---|
ESTs | BG205103 |
mRNA | AB528770 |
Sequence information
Nucleotide sequence |
ATGAAAAACCACACAGTAATAAGAACTTTTATCCTGCTGGGACTGACAGGTGACCCACAC CTGCAAGTTCTGCTTTTTATCTTTCTATTTCTCACCTACATGTTGAGTGTAACAGGGAAC CTGACTATTATCACCCTCACATTGGTGGACCACCACCTTAAAACTCCTATGTACTTCTTT CTCAGAAATTTTTCCTTCTTAGAAGTCTCATTTACTACAGTCTGCATTCCCAGATTCTTG TACAATATATCAATGGGGGACAATACCATTACCTACAATGCTTGTGCCAGTCAAATATTC TTTGTTATTCTCTTTGGAGCAACAGAATTTTTTCTCTTGGCAGCCATGTCCTATGACCGC TATGTGGCCATCTGTAAACCCCTTCATTATGTGGTCATCATGAACAACAGGGTGTGTACC TTATTAGTTCTCTGCTGTTGGGTGGCTGGCTTGATGATCATTGTTCCACCACTTAGCTTA GGCCTCCAGCTCGAATTCTGTGACTCCAATGCCATTGATCATTTTAGCTGTGATGCAGGT CCTCTCCTAAAGATCTCATGCTCAGATACATGGGTAATAGAACAGATGGTTATACTTATG GCTGTATTTGCACTCATTATCACCCTAGTTTGTGTGATTCTGTCCTACTTGTACATAGTC AGAACAATTCTGAAGTTCCCTTCTGTTCAGCAAAGGAAAAAGGCCTTTTCTACCTGTTCA TCCCACATGATTGTGGTTTCCATTGCCTATGGAAGCTGCATCTTCATCTATATCAAGCCC TCTGCAAAAGATGAGGTGGCCATAAATAAAGGAGTTTCAGTTCTTACTACTTCTGTCGCA CCCTTGTTGAACCCCTTCATTTACACCTTGAGGAACAAGCAAGTGAAACAAGCTTTCAGT GACTCTATAAAGAGGATTGCATTTCTCTCAAAGAAG |
Conceptual translation |
MKNHTVIRTFILLGLTGDPHLQVLLFIFLFLTYMLSVTGNLTIITLTLVDHHLKTPMYFF LRNFSFLEVSFTTVCIPRFLYNISMGDNTITYNACASQIFFVILFGATEFFLLAAMSYDR YVAICKPLHYVVIMNNRVCTLLVLCCWVAGLMIIVPPLSLGLQLEFCDSNAIDHFSCDAG PLLKISCSDTWVIEQMVILMAVFALIITLVCVILSYLYIVRTILKFPSVQQRKKAFSTCS SHMIVVSIAYGSCIFIYIKPSAKDEVAINKGVSVLTTSVAPLLNPFIYTLRNKQVKQAFS DSIKRIAFLSKK Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
12 | 55,846,204 | 55,846,203 | Ins(1) | -/G | rs34885470 (DbSNP) | |
12 | 55,846,773 | 55,846,773 | NS | A/G | K/R | rs73339457 (DbSNP) |
12 | 55,846,538 | 55,846,538 | NS | C/G | P/A | rs11171466 (DbSNP) |
12 | 55,846,623 | 55,846,623 | NS | C/T | P/L | rs11171467 (DbSNP) |
12 | 55,846,890 | 55,846,890 | NS | C/T | A/V | rs74092333 (DbSNP) |
12 | 55,846,649 | 55,846,649 | NS | G/T | D/Y | rs12817326 (DbSNP) |
12 | 55,846,731 | 55,846,731 | NS | G/T | G/V | rs12810501 (DbSNP) |
12 | 55,453,010 | 55,453,010 | NS | T/A | V/E | 1000GP (CEU) |
12 | 55,452,839 | 55,452,839 | NS | T/C | L/P | 1000GP (CEU) |
12 | 55,452,754 | 55,452,754 | NS | C/G | P/A | 1000GP (CHBJPT) |
12 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI, YRI) |
12 | 100 | -100 | NS | A/G | I/V | 1000GP (YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
12 | 55,832,210 | 56,001,052 | CopyNumber | Variation_4780 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
I154V | P181A | L209P | Q231H | I244T | K259R | V266E | A298V | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|
1 | I | P | L | Q | I | K | V | A | 80.49 | 0.131 |
2 | I | P | P | Q | I | K | V | A | 10.75 | 0.131 |
3 | I | A | L | Q | I | K | V | A | 2.69 | 0.131 |
4 | I | P | L | Q | I | R | V | A | 2.38 | 0.131 |
5 | I | P | L | Q | I | K | V | V | 2.15 | 0.131 |
6 | I | P | L | Q | T | K | V | A | 1.00 | 0.131 |
7 | I | P | L | H | I | K | V | A | 0.15 | 0.131 |
8 | I | P | P | Q | I | K | E | A | 0.15 | 0.131 |
9 | I | P | L | Q | I | R | V | V | 0.15 | 0.131 |
10 | V | P | P | Q | I | K | V | A | 0.08 | 0.131 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR6C2.aApr07-unspliced | main_exon | CDS | chr12 | 55,452,214 | 55,453,149 | + |
3UTR | chr12 | 55,453,149 | 55,453,152 | + |