OR6K2 Olfactory Receptor
| Gene Symbol | OR6K21 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.61 (pseudogene) |
| Aliases | OR1-17, HsOR1.4.12, ORL3024 |
| External Ids | HGNC: 15029 GeneBank: AB065634, BK004196, NM_001005279 ORDB: ORL3024 |
| Build #39 labels | OR6K2 |
| Chromosomal location | 1:158,699,681-158,700,652 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6K3 | 61.97% | 305 |
| OR6K4P | 62.63% | 297 |
| OR6K6 | 63.12% | 301 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6K6 | 65% | 299 |
| Mouse | Or6k2 | 87% | 312 |
| Rat | Or6k2 | 87% | 312 |
| Cow | OR6K6 | 62% | 311 |
| Orang | OR6K17 | 95% | 231 |
| Horse | OR6K4 | 62% | 306 |
| Chimp | OR6K3 | 63% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137023 |
Sequence information
| Nucleotide sequence |
ATGGAGAGCCCCAATCGAACCACCATTCAGGAGTTTATCTTCTCCGCTTTCCCTTATTCC TGGGTTAAGTCTGTTGTCTGCTTTGTTCCACTGCTCTTCATCTATGCTTTCATTGTTGTT GGAAACCTGGTCATCATCACAGTGGTCCAGTTGAATACTCACCTCCACACTCCCATGTAT ACTTTTATCAGTGCTCTTTCTTTCCTGGAGATTTGGTATACCACAGCCACAATCCCAAAG ATGCTGTCTAGCCTGCTTAGTGAGAGGAGCATTTCCTTCAATGGTTGTCTCCTGCAGATG TATTTCTTCCATTCCACCGGCATCTGTGAGGTGTGTCTCTTGACAGTTATGGCCTTTGAC CACTACCTGGCCATATGCAGCCCTCTTCATTATCCCTCTATCATGACCCCCAAGCTATGT ACCCAACTGACTTTAAGTTGCTGTGTTTGTGGCTTTATCACACCCCTTCCTGAGATTGCC TGGATCTCTACACTGCCATTTTGTGGTTCGAATCACCTTGAACATATCTTCTGTGACTTC CTCCCAGTGCTGCGTCTGGCCTGCACAGACACACGAGCCATCGTCATGATTCAGGTAGTG GATGTCATTCATGCAGTGGAGATTATTACAGCTGTGATGCTCATCTTCATGTCCTACGAT GGTATTGTGGCTGTAATTCTACGTATTCATTCAGCTGGAGGCCGCCGCACAGCATTTTCC ACGTGTGTCTCTCACTTCATTGTCTTTTCGCTCTTCTTTGGCAGTGTGACTCTCATGTAC CTACGCTTCTCTGCCACCTACTCTTTGTTCTGGGATATAGCCATTGCTCTGGCCTTTGCA GTTTTGTCTCCCTTCTTCAACCCCATTATCTATAGCCTGAGGAATAAAGAAATAAAAGAA GCTATAAAAAAGCACATAGGTCAAGCTAAGATATTTTTTTCCGTAAGACCAGGGACCTCA AGTAAGATATTT |
| Conceptual translation |
MESPNRTTIQEFIFSAFPYSWVKSVVCFVPLLFIYAFIVVGNLVIITVVQLNTHLHTPMY TFISALSFLEIWYTTATIPKMLSSLLSERSISFNGCLLQMYFFHSTGICEVCLLTVMAFD HYLAICSPLHYPSIMTPKLCTQLTLSCCVCGFITPLPEIAWISTLPFCGSNHLEHIFCDF LPVLRLACTDTRAIVMIQVVDVIHAVEIITAVMLIFMSYDGIVAVILRIHSAGGRRTAFS TCVSHFIVFSLFFGSVTLMYLRFSATYSLFWDIAIALAFAVLSPFFNPIIYSLRNKEIKE AIKKHIGQAKIFFSVRPGTSSKIF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | G/A | R/C | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | A/G | F/F | 1000GP (YRI) |
| 1 | 158,669,662 | 158,669,662 | SYN | A/G | L/L | rs41273535 (DbSNP) |
| 1 | 158,669,684 | 158,669,684 | SYN | A/G | F/F | rs61322025 (DbSNP) |
| 1 | 158,669,968 | 158,669,968 | NS | A/T | F/I | rs6686179 (DbSNP) |
| 1 | 158,669,977 | 158,669,977 | NS | C/G | V/L | rs423141 (DbSNP) |
| 1 | 158,670,426 | 158,670,426 | NS | T/C | Q/R | rs413029 (DbSNP) |
| 1 | 158,699,872 | 158,699,872 | SYN | G/A | L/L | 1000GP (CEU) |
| 1 | 158,699,992 | 158,699,992 | NS | C/T | G/S | 1000GP (CHBJPT) |
| 1 | 158,700,009 | 158,700,009 | NS | A/T | I/N | 1000GP (CEU) |
| 1 | 158,700,257 | 158,700,257 | SYN | G/A | P/P | 1000GP (CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R236C | G221S | I159F | L156V | P155S | C140R | S83F | R6Q | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | G | I | L | P | C | S | R | 88.63 | 0.678 |
| 2 | R | G | F | L | P | C | S | R | 2.92 | 0.678 |
| 3 | R | S | I | L | P | C | S | R | 2.92 | 0.678 |
| 4 | R | G | I | V | P | C | S | Q | 2.53 | 0.678 |
| 5 | R | G | I | L | S | C | S | R | 1.61 | 0.678 |
| 6 | C | G | F | L | P | C | S | R | 0.77 | 0.678 |
| 7 | R | G | I | L | P | C | S | Q | 0.31 | 0.678 |
| 8 | R | G | I | L | P | C | F | R | 0.15 | 0.678 |
| 9 | R | G | I | L | P | R | S | R | 0.15 | 0.678 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6K2.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,699,678 | 158,699,681 | - |
| CDS | chr1 | 158,699,681 | 158,700,652 | - | ||