OR6K3 Olfactory Receptor
| Gene Symbol | OR6K31 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR1-18, HsOR1.4.13, ORL3034 |
| External Ids | HGNC: 15030 GeneBank: AB065633, BK004197, NM_001005327 ORDB: ORL3034 |
| Build #39 labels | OR6K3 |
| Chromosomal location | 1:158,717,171-158,718,115 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6K4P | 80.61% | 294 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6K4 | 82% | 304 |
| Mouse | Or6k3 | 86% | 293 |
| Rat | Or6k3-ps | 87% | 311 |
| Cow | OR6K4 | 81% | 309 |
| Orang | OR6K3P | 96% | 257 |
| Horse | OR6K4 | 81% | 301 |
| Chimp | OR6K4 | 81% | 308 |
Sequence information
| Nucleotide sequence |
ATGGAGAGCGGAAACCAATCAACAGTGACTGAATTTATCTTCACTGGATTCCCTCAGCTT CAGGATGGTAGTCTCCTGTACTTCTTTCCTTTACTTTTCATCTATACTTTTATTATCATT GATAACTTATTAATCTTCTCTGCTGTAAGGCTGGACACCCATCTCCACAACCCCATGTAT AATTTTATCAGTATATTTTCCTTTCTGGAGATCTGGTACACCACAGCCACCATTCCCAAG ATGCTCTCCAACCTCATCAGTGAAAAGAAGGCCATCTCAATGACTGGCTGCATCTTGCAG ATGTATTTCTTCCACTCACTTGAAAACTCAGAGGGGATCTTGCTGACCACCATGGCCATT GACAGATACGTTGCCATCTGCAACCCTCTTCGCTATCAAATGATCATGACCCCCCGGCTC TGTGCTCAACTCTCTGCAGGTTCCTGCCTCTTCGGTTTCCTTATCCTGCTTCCCGAGATT GTGATGATTTCCACACTGCCTTTCTGTGGGCCCAACCAAATCCATCAGATCTTCTGTGAC TTGGTCCCTGTGCTAAGCCTGGCCTGTACAGACACGTCCATGATTCTGATTGAGGATGTG ATTCATGCTGTGACCATCATCATTACCTTCCTAATCATTGCCCTGTCCTATGTAAGAATT GTCACTGTGATATTGAGGATTCCCTCTTCTGAAGGGAGGCAAAAGGCTTTTTCTACCTGT GCAGGCCACCTCATGGTCTTCCCGATATTCTTTGGCAGTGTATCACTCATGTACTTGCGT TTCAGCGACACTTATCCACCAGTTTTGGACACAGCCATTGCACTGATGTTTACTGTACTT GCTCCATTCTTCAATCCCATCATTTATAGCCTGAGAAACAAGGACATGAACAATGCGATT AAAAAACTGTTCTGTCTTCAAAAAGTGTTGAACAAGCCTGGAGGT |
| Conceptual translation |
MESGNQSTVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMY NFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAI DRYVAICNPLRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCD LVPVLSLACTDTSMILIEDVIHAVTIIITFLIIALSYVRIVTVILRIPSSEGRQKAFSTC AGHLMVFPIFFGSVSLMYLRFSDTYPPVLDTAIALMFTVLAPFFNPIIYSLRNKDMNNAI KKLFCLQKVLNKPGG Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | A/G | V/A | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | C/T | A/A | 1000GP (YRI) |
| 1 | 158,687,009 | 158,687,009 | SYN | C/T | A/A | rs857701 (DbSNP) |
| 1 | 158,687,031 | 158,687,031 | NS | C/T | R/K | rs16840675 (DbSNP) |
| 1 | 158,687,119 | 158,687,119 | NS | C/T | D/N | rs857702 (DbSNP) |
| 1 | 158,687,163 | 158,687,163 | NS | A/G | L/P | rs28568406 (DbSNP) |
| 1 | 158,687,224 | 158,687,224 | NS | A/G | S/P | rs857703 (DbSNP) |
| 1 | 158,687,451 | 158,687,451 | NS | C/T | G/D | rs73030055 (DbSNP) |
| 1 | 158,687,477 | 158,687,477 | NS | G/T | H/Q | rs857704 (DbSNP) |
| 1 | 158,687,896 | 158,687,896 | NS | C/T | G/R | rs857705 (DbSNP) |
| 1 | 158,717,373 | 158,717,373 | NS | G/A | P/L | 1000GP (CEU, CHBJPT) |
| 1 | 158,717,434 | 158,717,434 | NS | G/A | P/S | 1000GP (CEU, CHBJPT) |
| 1 | 158,717,687 | 158,717,687 | SYN | T/C | Q/Q | 1000GP (CHBJPT) |
| 1 | 158,718,106 | 158,718,106 | NS | C/T | G/R | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V309A | D263N | P248L | P228S | V200M | G152D | Q143H | G96A | G4R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | V | D | P | P | V | G | Q | G | G | 40.86 | 0.029 |
| 2 | V | D | L | S | V | G | Q | G | G | 30.03 | 0.029 |
| 3 | V | D | P | P | V | G | Q | G | R | 18.59 | 0.029 |
| 4 | V | D | L | P | V | G | Q | G | G | 3.76 | 0.029 |
| 5 | V | N | L | P | V | G | H | G | R | 3.30 | 0.029 |
| 6 | V | D | L | P | V | D | Q | G | G | 2.23 | 0.029 |
| 7 | A | D | P | P | V | G | Q | G | G | 0.38 | 0.029 |
| 8 | V | D | P | P | M | G | Q | G | G | 0.31 | 0.029 |
| 9 | V | D | P | P | V | G | Q | A | R | 0.23 | 0.029 |
| 10 | V | D | P | P | V | D | Q | G | G | 0.15 | 0.029 |
| 11 | V | D | P | S | V | G | Q | G | G | 0.08 | 0.029 |
| 12 | V | N | L | P | V | G | H | G | G | 0.08 | 0.029 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6K3.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,717,168 | 158,717,171 | - |
| CDS | chr1 | 158,717,171 | 158,718,115 | - | ||
| 5UTR | chr1 | 158,718,115 | 158,718,163 | - | ||