OR6M1 Olfactory Receptor
| Gene Symbol | OR6M11 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.02 (functional) |
| Aliases | OR11-271, HsOR11.18.2, ORL3369 |
| External Ids | HGNC: 14711 GeneBank: AB065762, AF399606, AY284165-AY284196, BK004493, NM_001005325 ORDB: ORL3369 |
| Build #39 labels | OR6M1 |
| Chromosomal location | 11:123,805,411-123,806,349 (-) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6M2P | 72.99% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6M2 | 78% | 311 |
| Mouse | Or6s1 | 53% | 308 |
| Rat | Or6s1 | 52% | 315 |
| Cow | OR6M7 | 77% | 310 |
| Orang | OR6M1P | 95% | 312 |
| Orang | OR6M1BP | 95% | 248 |
| Horse | OR6M8 | 79% | 313 |
| Chimp | OR6M2P | 73% | 313 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136931 |
| GNF Atlas2 | gnf1h02118_at |
Sequence information
| Nucleotide sequence |
ATGGGAAACTGGAGCACTGTGACTGAAATCACCCTAATTGCCTTCCCAGCTCTCCTGGAG ATTCGAATATCTCTCTTCGTGGTTCTTGTGGTAACTTACACATTAACAGCAACAGGAAAC ATCACCATCATCTCCCTGATATGGATTGATCATCGCCTGCAAACTCCAATGTACTTCTTC CTCAGTAATTTGTCCTTTCTGGATATCTTATACACCACTGTCATTACCCCAAAGTTGTTG GCCTGCCTCCTAGGAGAAGAGAAAACCATATCTTTTGCTGGTTGCATGATCCAAACATAT TTCTACTTCTTTCTGGGGACGGTGGAGTTTATCCTCTTGGCGGTGATGTCCTTTGACCGC TACATGGCTATCTGCGACCCACTGCACTACACGGTCATCATGAACAGCAGGGCCTGCCTT CTGCTGGTTCTGGGATGCTGGGTGGGAGCCTTCCTGTCTGTGTTGTTTCCAACCATTGTA GTGACAAGGCTACCTTACTGTAGGAAAGAAATTAATCATTTCTTCTGTGACATTGCCCCT CTTCTTCAGGTGGCCTGTATAAATACTCACCTCATTGAGAAGATAAACTTTCTCCTCTCT GCCCTTGTCATCCTGAGCTCCCTGGCATTCACTACTGGGTCCTACGTGTACATAATTTCT ACCATCCTGCGTATCCCCTCCACCCAGGGCCGTCAGAAAGCTTTTTCTACCTGTGCTTCT CACATCACTGTTGTCTCCATTGCCCACGGGAGCAACATCTTTGTGTATGTGAGACCCAAT CAGAACTCCTCACTGGATTATGACAAGGTGGCCGCTGTCCTCATCACAGTGGTGACCCCT CTCCTGAACCCTTTTATCTACAGCTTGAGGAATGAGAAGGTACAGGAAGTGTTGAGAGAG ACAGTGAACAGAATCATGACCTTGATACAAAGGAAAACT |
| Conceptual translation |
MGNWSTVTEITLIAFPALLEIRISLFVVLVVTYTLTATGNITIISLIWIDHRLQTPMYFF LSNLSFLDILYTTVITPKLLACLLGEEKTISFAGCMIQTYFYFFLGTVEFILLAVMSFDR YMAICDPLHYTVIMNSRACLLLVLGCWVGAFLSVLFPTIVVTRLPYCRKEINHFFCDIAP LLQVACINTHLIEKINFLLSALVILSSLAFTTGSYVYIISTILRIPSTQGRQKAFSTCAS HITVVSIAHGSNIFVYVRPNQNSSLDYDKVAAVLITVVTPLLNPFIYSLRNEKVQEVLRE TVNRIMTLIQRKT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 123,676,231 | 123,676,231 | NS | G/T | T/K | rs4936845 (DbSNP) |
| 11 | 123,676,413 | 123,676,413 | SYN | A/G | Y/Y | rs7952150 (DbSNP) |
| 11 | 123,805,680 | 123,805,680 | NS | G/A | R/C | 1000GP (CEU, CHBJPT) |
| 11 | 123,805,523 | 123,805,523 | NS | G/T | T/K | 1000GP (CEU, CHBJPT) |
| 11 | 123,805,705 | 123,805,705 | SYN | G/A | Y/Y | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | NS | G/T | T/K | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/A | Y/Y | 1000GP (YRI, YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T276K | R231H | R224H | R224C | K194N | T158I | G94D | V74L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | T | R | R | R | K | T | G | V | 59.75 | 0.047 |
| 2 | K | R | R | R | K | T | G | V | 22.04 | 0.047 |
| 3 | T | R | R | C | K | T | G | V | 12.44 | 0.047 |
| 4 | T | R | H | R | K | T | G | V | 1.77 | 0.047 |
| 5 | T | R | R | R | K | I | G | V | 1.61 | 0.047 |
| 6 | T | R | R | C | N | T | G | V | 0.77 | 0.047 |
| 7 | K | H | R | R | K | T | G | V | 0.61 | 0.039 |
| 8 | T | R | R | R | K | T | D | V | 0.54 | 0.047 |
| 9 | T | R | R | R | N | T | G | V | 0.15 | 0.047 |
| 10 | T | R | R | R | K | T | G | L | 0.15 | 0.047 |
| 11 | K | R | R | C | K | T | G | V | 0.08 | 0.047 |
| 12 | K | R | R | R | K | I | G | V | 0.08 | 0.047 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6M1.aApr07-unspliced | main_exon | 3UTR | chr11 | 123,805,408 | 123,805,411 | - |
| CDS | chr11 | 123,805,411 | 123,806,349 | - | ||