OR6N2 Olfactory Receptor
| Gene Symbol | OR6N21 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | N |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR1-23, HsOR1.4.18, ORL3005 |
| External Ids | HGNC: 15035 GeneBank: AB065630, BK004200, NM_001005278 ORDB: ORL3005 |
| Build #39 labels | OR6N2 |
| Chromosomal location | 1:158,776,685-158,777,635 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6N1 | 66.34% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6N1 | 67% | 305 |
| Mouse | Or6n2 | 86% | 316 |
| Rat | Or6n2 | 85% | 316 |
| Cow | OR6N1 | 66% | 309 |
| Orang | OR6N1 | 66% | 309 |
| Horse | OR6N1 | 68% | 309 |
| Chimp | OR6N1 | 67% | 309 |
Sequence information
| Nucleotide sequence |
ATGGATCAATACAACCATTCAAGCCTGGCTGAATTTGTGTTCCTTGGCTTTGCCAGTGTG GGCTATGTCAGGGGCTGGCTTTTTGTCCTGCTGCTATTGGCATACCTGTTCACCATCTGT GGTAACATGCTCATCTTCTCAGTCATCCGACTGGATGCAGCTCTGCACACACCTATGTAC CACTTTGTCAGTGTTCTTTCCTTCTTGGAGTTGTGGTATACAGCTACCACTATCCCTAAG ATGTTGTCTAATATTCTCAGTGAGAAGAAAACCATTTCTTTTGCAGGATGCCTCCTTCAG ACCTACTTCTTCCACTCCTTGGGAGCGTCTGAATGCTACCTTCTTACAGCCATGGCCTAT GATAGATACCTGGCCATTTGTCGGCCCCTCCACTACCCTATAATTATGACCACCACACTC TGTGCCAAGATGGCTGCTGCTTGTTGGACTTGTGGCTTCCTGTGTCCCATTTCTGAGGTC ATCCTTGCCTCCCAGCTCCCATTTTGTGCTTACAATGAAATCCAACACATTTTCTGTGAC TTTCCACCTTTGCTGAGCTTGGCCTGCAAGGACACATCTGCTAACATTCTGGTGGACTTT GCCATTAATGCTTTCATAATTCTTATCACTTTCTTCTTTATCATGATTTCTTATGCAAGG ATCATTGGGGCTGTGCTGAAGATAAAAACAGCATCAGGAAGAAAGAAGGCCTTTTCTACC TGTGCCTCACATCTTGCTGTGGTCCTCATCTTCTTTGGGAGCATCATCTTCATGTATGTG CGGCTAAAGAAGAGCTATTCCCTGACCCTTGACCGAACACTTGCTATAGTTTACTCCGTA CTAACACCAATGGTCAATCCAATTATCTACAGTCTTCGTAACAAGGAAATCATTAAAGCT ATCAAGAGGACCATCTTCCAGAAGGGAGATAAAGCTAGTCTTGCTCATCTT |
| Conceptual translation |
MDQYNHSSLAEFVFLGFASVGYVRGWLFVLLLLAYLFTICGNMLIFSVIRLDAALHTPMY HFVSVLSFLELWYTATTIPKMLSNILSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAY DRYLAICRPLHYPIIMTTTLCAKMAAACWTCGFLCPISEVILASQLPFCAYNEIQHIFCD FPPLLSLACKDTSANILVDFAINAFIILITFFFIMISYARIIGAVLKIKTASGRKKAFST CASHLAVVLIFFGSIIFMYVRLKKSYSLTLDRTLAIVYSVLTPMVNPIIYSLRNKEIIKA IKRTIFQKGDKASLAHL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 158,746,815 | 158,746,815 | NS | A/G | V/A | rs12027473 (DbSNP) |
| 1 | 158,746,678 | 158,746,678 | NS | C/T | V/I | rs41273541 (DbSNP) |
| 1 | 158,746,847 | 158,746,847 | SYN | A/G | S/S | rs16841094 (DbSNP) |
| 1 | 158,777,057 | 158,777,057 | SYN | A/G | S/S | 1000GP (CEU, CHBJPT) |
| 1 | 158,776,888 | 158,776,888 | NS | T/C | I/V | 1000GP (CEU, CHBJPT) |
| 1 | 158,777,025 | 158,777,025 | NS | G/A | A/V | 1000GP (CHBJPT) |
| 1 | 100 | -100 | nonsense SNP | G/A | R/* | 1000GP (YRI) |
| 1 | 100 | -100 | NS | T/C | I/V | 1000GP (YRI) |
| 1 | 100 | -100 | SYN | A/G | S/S | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 158,744,475 | 158,747,525 | CopyNumber | #27 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R272* | I250V | A204V | D199V | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | R | I | A | D | 86.71 | 0.060 |
| 2 | R | V | A | D | 11.29 | 0.060 |
| 3 | R | I | V | D | 1.54 | 0.060 |
| 4 | * | V | A | D | 0.31 | 1.200 |
| 5 | R | V | A | V | 0.08 | 0.060 |
| 6 | * | I | A | D | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6N2.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,776,682 | 158,776,685 | - |
| CDS | chr1 | 158,776,685 | 158,777,635 | - | ||