OR6T1 Olfactory Receptor
| Gene Symbol | OR6T11 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR11-277, HsOR11.18.7, ORL3378 |
| External Ids | HGNC: 14848 GeneBank: AB065759, BK004315, NM_001005187 ORDB: ORL3378 |
| Build #39 labels | OR6T1 |
| Chromosomal location | 11:123,942,870-123,943,838 (-) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6E1P | 50.67% | 300 |
| OR6J1 | 50.16% | 315 |
| OR6M1 | 52.49% | 301 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6T1P | 85% | 307 |
| Mouse | Or6c66b | 51% | 299 |
| Rat | Or6e1 | 49% | 318 |
| Cow | OR6T8P | 68% | 298 |
| Orang | OR6T1P | 93% | 318 |
| Orang | OR6T1BP | 92% | 318 |
| Horse | OR6T1CP | 82% | 317 |
| Chimp | OR6M1 | 53% | 302 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136906 |
| GNF Atlas2 | gnf1h05560_at |
Sequence information
| Nucleotide sequence |
ATGAACCCTGAAAACTGGACTCAGGTAACAAGCTTTGTCCTTCTGGGTTTCCCCAGTAGC CACCTCATACAGTTCCTGGTGTTCCTGGGGTTAATGGTGACCTACATTGTAACAGCCACA GGCAAGCTGCTAATTATTGTGCTCAGCTGGATAGACCAACGCCTGCACATACAGATGTAC TTCTTCCTGCGGAATTTCTCCTTCCTGGAGCTGTTGCTGGTAACTGTTGTGGTTCCCAAG ATGCTTGTCGTCATCCTCACGGGGGATCACACCATCTCATTTGTCAGCTGCATCATCCAG TCCTACCTCTACTTCTTTCTAGGCACCACTGACTTCTTCCTCTTGGCCGTCATGTCTCTG GATCGTTACCTGGCAATCTGCCGACCACTCCGCTATGAGACCCTGATGAATGGCCATGTC TGTTCCCAACTAGTGCTGGCCTCCTGGCTAGCTGGATTCCTCTGGGTCCTTTGCCCCACT GTCCTCATGGCCAGCCTGCCTTTCTGTGGCCCCAATGGTATTGACCACTTCTTTCGTGAC AGTTGGCCCTTGCTCAGGCTTTCTTGTGGGGACACCCACCTGCTGAAACTGGTGGCTTTC ATGCTCTCTACGTTGGTGTTACTGGGCTCACTGGCTCTGACCTCAGTTTCCTATGCCTGC ATTCTTGCCACTGTTCTCAGGGCCCCTACAGCTGCTGAGCGAAGGAAAGCGTTTTCCACT TGCGCCTCGCATCTTACAGTGGTGGTCATCATCTATGGCAGTTCCATCTTTCTCTACATT CGTATGTCAGAGGCTCAGTCCAAACTGCTCAACAAAGGTGCCTCCGTCCTGAGCTGCATC ATCACACCCCTCTTGAACCCATTCATCTTCACTCTCCGCAATGACAAGGTGCAGCAAGCA CTGAGAGAAGCCTTGGGGTGGCCCAGGCTCACTGCTGTGATGAAACTGAGGGTCACAAGT CAAAGGAAA |
| Conceptual translation |
MNPENWTQVTSFVLLGFPSSHLIQFLVFLGLMVTYIVTATGKLLIIVLSWIDQRLHIQMY FFLRNFSFLELLLVTVVVPKMLVVILTGDHTISFVSCIIQSYLYFFLGTTDFFLLAVMSL DRYLAICRPLRYETLMNGHVCSQLVLASWLAGFLWVLCPTVLMASLPFCGPNGIDHFFRD SWPLLRLSCGDTHLLKLVAFMLSTLVLLGSLALTSVSYACILATVLRAPTAAERRKAFST CASHLTVVVIIYGSSIFLYIRMSEAQSKLLNKGASVLSCIITPLLNPFIFTLRNDKVQQA LREALGWPRLTAVMKLRVTSQRK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | R/W | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | A/A | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 123,813,795 | 123,813,795 | NS | C/T | V/I | rs7937317 (DbSNP) |
| 11 | 123,813,823 | 123,813,823 | SYN | A/G | C/C | rs7129884 (DbSNP) |
| 11 | 123,813,915 | 123,813,915 | SYN | A/G | L/L | rs12274518 (DbSNP) |
| 11 | 123,813,940 | 123,813,940 | SYN | C/G | L/L | rs7130003 (DbSNP) |
| 11 | 123,814,261 | 123,814,261 | SYN | A/G | V/V | rs6590020 (DbSNP) |
| 11 | 123,814,356 | 123,814,356 | NS | A/G | W/R | rs6590021 (DbSNP) |
| 11 | 123,814,478 | 123,814,478 | NS | A/G | I/T | rs6590022 (DbSNP) |
| 11 | 123,814,489 | 123,814,489 | SYN | A/G | S/S | rs4936859 (DbSNP) |
| 11 | 123,943,088 | 123,943,088 | NS | T/C | I/V | 1000GP (CHBJPT) |
| 11 | 123,943,116 | 123,943,116 | SYN | G/A | C/C | 1000GP (CEU, CHBJPT) |
| 11 | 123,943,233 | 123,943,233 | SYN | G/C | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 123,943,554 | 123,943,554 | SYN | G/A | V/V | 1000GP (CHBJPT) |
| 11 | 123,943,649 | 123,943,649 | NS | G/A | R/W | 1000GP (CHBJPT) |
| 11 | 123,943,771 | 123,943,771 | NS | A/G | I/T | 1000GP (CHBJPT) |
| 11 | 123,943,782 | 123,943,782 | SYN | A/G | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 123,943,799 | 123,943,799 | NS | G/A | L/F | 1000GP (CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V276I | I251V | S243L | A228D | N137T | R64W | I23T | L14F | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | V | I | S | A | N | R | I | L | 91.78 | 1.000 |
| 2 | V | V | S | A | N | W | T | L | 6.14 | 1.000 |
| 3 | V | I | L | A | N | R | I | L | 0.54 | 1.000 |
| 4 | I | I | S | A | N | R | I | L | 0.38 | 1.000 |
| 5 | V | V | S | A | N | W | I | L | 0.38 | 1.000 |
| 6 | V | I | S | D | N | R | I | L | 0.31 | 1.000 |
| 7 | V | I | S | A | T | R | I | L | 0.23 | 1.000 |
| 8 | V | I | S | A | N | W | T | L | 0.08 | 1.000 |
| 9 | V | I | S | A | N | R | I | F | 0.08 | 1.000 |
| 10 | V | I | S | A | N | W | I | L | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6T1.aApr07-unspliced | main_exon | 3UTR | chr11 | 123,942,867 | 123,942,870 | - |
| CDS | chr11 | 123,942,870 | 123,943,838 | - | ||