OR7A17 Olfactory Receptor
| Gene Symbol | OR7A171 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.02 (functional) |
| Aliases | OR19-20, HSHTPCRX19, HsOR19.3.6, ORL1028 |
| External Ids | HGNC: 8363 GeneBank: AF399541, BK004206, HSHTPRX19, NM_030901 ORDB: ORL1028 |
| Build #39 labels | OR7A17 |
| Chromosomal location | 19:14,880,429-14,881,355 (-) |
| Cluster | 19@15a |
| Synteny | CLIC#45 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7A10 | 82.52% | 309 |
| OR7A1P | 80.39% | 306 |
| OR7A2P | 80.66% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7A53 | 79% | 302 |
| Mouse | Or7a40 | 76% | 308 |
| Rat | Or7a41 | 77% | 304 |
| Cow | OR7A65 | 80% | 308 |
| Orang | OR7A17P | 96% | 305 |
| Horse | OR7A96 | 82% | 305 |
| Chimp | OR7A17P | 98% | 272 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | AI909504 |
| mRNA | X64993 |
| GNF Atlas2 | 208509_s_at |
Sequence information
| Nucleotide sequence |
ATGGAACCAGAGAATGACACAGGGATTTCAGAATTTGTTCTTCTGGGACTTTCTGAGGAA CCAGAATTGCAGCCCTTCCTCTTTGGGCTGTTTCTGTCCATGTACCTGGTCACTGTGCTC GGGAATCTGCTCATCATCCTGGCCACAATCTCAGACTCCCACCTCCACACCCCCATGTAC TTCTTCCTCTCCAACCTGTCCTTTGCAGACATCTGTTTCATCTCCACTACAATCCCAAAG ATGCTCATTAACATCCAGACACAGAGCAGAGTCATCACCTATGCAGGCTGCATCACCCAG ATGTGCTTTTTTGTACTTTTTGGAGGGTTAGACAGCTTACTCCTGGCTGTGATGGCCTAT GATCGGTTTGTGGCCATCTGTCATCCTCTGCACTACACAGTCATCATGAACCCTCGGCTC TGTGGACTCCTGGTTCTGGCATCCTGGATGATTGCTGCCCTGAATTCCTTGTCACAAAGC TTAATGGTATTGTGGCTGTCCTTCTGCACAGACTTGGAAATCCCCCACTTTTTCTGTGAA CTTAATCAGGTCATCCACCTTGCCTGTTCTGACACCTTTCTTAATGACATGGGGATGTAT TTTGCAGCAGGGCTGCTGGCTGGTGGTCCCCTTGTGGGGATCCTTTGCTCTTACTCTAAG ATAGTTTCCTCCATACGTGCAATCTCATCAGCTCAGGGGAAGTACAAGGCATTTTCCACC TGTGCATCACACCTCTCAGTTGTCTCTTTATTTTGTTGTACGGGCCTAGGTGTGTACCTT ACTTCTGCTGCAACCCACAACTCACACACAAGTGCAACAGCCTCAGTGATGTACACTGTG GCCACCCCCATGCTGAACCCCTTTATCTACAGTCTGAGGAATAAAGACATAAAGAGGGCT CTGAAAATGTCCTTCAGAGGAAAGCAA |
| Conceptual translation |
MEPENDTGISEFVLLGLSEEPELQPFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMY FFLSNLSFADICFISTTIPKMLINIQTQSRVITYAGCITQMCFFVLFGGLDSLLLAVMAY DRFVAICHPLHYTVIMNPRLCGLLVLASWMIAALNSLSQSLMVLWLSFCTDLEIPHFFCE LNQVIHLACSDTFLNDMGMYFAAGLLAGGPLVGILCSYSKIVSSIRAISSAQGKYKAFST CASHLSVVSLFCCTGLGVYLTSAATHNSHTSATASVMYTVATPMLNPFIYSLRNKDIKRA LKMSFRGKQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | G/T | S/R | 1000GP (YRI, YRI) |
| 19 | 100 | -100 | SYN | T/G | S/S | 1000GP (YRI, YRI, YRI) |
| 19 | 14,880,831 | 14,880,831 | SYN | G/A | P/P | 1000GP (CEU, CHBJPT) |
| 19 | 14,881,219 | 14,881,219 | NS | A/G | I/T | 1000GP (CEU) |
| 19 | 14,881,230 | 14,881,230 | SYN | A/G | N/N | 1000GP (CEU, CHBJPT) |
| 19 | 14,881,233 | 14,881,233 | SYN | C/T | G/G | 1000GP (CEU, CHBJPT) |
| 19 | 14,991,399 | 14,991,399 | NS | C/T | G/S | rs12461347 (DbSNP) |
| 19 | 14,991,439 | 14,991,439 | SYN | G/T | S/S | rs34590588 (DbSNP) |
| 19 | 14,991,459 | 14,991,459 | NS | C/T | A/T | rs13345394 (DbSNP) |
| 19 | 14,991,529 | 14,991,529 | Del(1) | -/C | rs5827261 (DbSNP) | |
| 19 | 14,991,635 | 14,991,635 | Del(1) | -/A | rs35659165 (DbSNP) | |
| 19 | 14,991,643 | 14,991,643 | SYN | A/G | P/P | rs10401818 (DbSNP) |
| 19 | 14,991,792 | 14,991,792 | Del(1) | -/T | rs34777619 (DbSNP) | |
| 19 | 14,991,963 | 14,991,963 | NS | A/C | S/A | rs10404119 (DbSNP) |
| 19 | 14,992,031 | 14,992,031 | NS | A/G | I/T | rs10405129 (DbSNP) |
| 19 | 14,992,042 | 14,992,042 | SYN | A/G | N/N | rs10405136 (DbSNP) |
| 19 | 14,992,045 | 14,992,045 | SYN | C/T | G/G | rs10404335 (DbSNP) |
| 19 | 14,992,058 | 14,992,058 | NS | A/G | V/A | rs10405148 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A237T | R226H | S112R | G96D | Y94C | N84D | A69S | I46T | V37A | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | A | R | S | G | Y | N | A | I | V | 61.37 | 0.022 |
| 2 | A | R | S | G | Y | N | S | T | V | 29.95 | 0.022 |
| 3 | T | R | S | G | Y | N | A | I | V | 3.00 | 0.061 |
| 4 | A | R | S | G | Y | N | S | I | V | 2.53 | 0.022 |
| 5 | A | R | S | G | Y | N | A | I | A | 1.23 | 0.022 |
| 6 | A | R | S | D | Y | N | A | I | V | 0.54 | 0.022 |
| 7 | T | R | S | G | Y | N | S | T | V | 0.31 | 0.061 |
| 8 | A | H | R | G | Y | N | A | I | V | 0.31 | 0.022 |
| 9 | A | R | S | G | Y | N | A | T | V | 0.23 | 0.022 |
| 10 | A | H | S | G | Y | N | A | I | V | 0.15 | 0.022 |
| 11 | A | R | S | G | C | N | S | T | V | 0.08 | 0.022 |
| 12 | A | R | S | G | C | N | A | I | V | 0.08 | 0.022 |
| 13 | T | R | S | G | Y | D | S | T | V | 0.08 | 0.061 |
| 14 | A | R | S | G | Y | D | A | I | V | 0.08 | 0.022 |
| 15 | A | R | S | D | Y | N | S | T | V | 0.08 | 0.022 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7A17.aApr07-unspliced | main_exon | 3UTR | chr19 | 14,880,326 | 14,880,429 | - |
| CDS | chr19 | 14,880,429 | 14,881,355 | - | ||
| 5UTR | chr19 | 14,881,355 | 14,881,452 | - | ||