OR7C1 Olfactory Receptor
| Gene Symbol | OR7C11 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0.02 (functional) |
| Aliases | OR19-16, CIT-HSP-146e8, TPCR86, OR19-5, HsOR19.3.1, ORL3767 |
| External Ids | HGNC: 8373 GeneBank: AF399546, BK004220, HSTPCR86P, NM_198944 ORDB: ORL3767 |
| Build #39 labels | OR7C1 |
| Chromosomal location | 19:14,799,177-14,800,136 (-) |
| Cluster | 19@15a |
| Synteny | CLIC#45 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7C2 | 77.81% | 320 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7C1B | 81% | 305 |
| Mouse | Or7c70 | 69% | 319 |
| Rat | Or7c70 | 70% | 318 |
| Cow | OR7C2 | 74% | 320 |
| Orang | OR7C1P | 92% | 318 |
| Horse | OR7C2 | 77% | 308 |
| Chimp | OR7C2 | 78% | 320 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DB338053 |
| mRNA | X89676 |
| GNF Atlas2 | 216690_at |
Sequence information
| Nucleotide sequence |
ATGGAAACAGGAAATCAAACACATGCCCAAGAATTTCTCCTCCTGGGATTTTCAGCAACG TCAGAGATTCAGTTCATTCTCTTTGGGCTGTTCCTCTCCATGTACCTAGTCACTTTCACC GGGAACCTGCTCATCATCCTGGCCATATGCTCAGACTCCCACCTCCACACCCCCATGTAC TTCTTCCTCTCCAACCTGTCTTTTGCTGACCTCTGTTTTACCTCCACGACTGTCCCAAAG ATGTTACTGAATATACTGACACAGAACAAATTCATAACATATGCAGGCTGTCTCAGTCAG ATTTTTTTTTTCACTTCATTTGGATGCCTGGACAATTTACTCTTGACCGTGATGGCCTAT GACCGCTTCGTGGCCGTCTGTCACCCCCTGCACTATACGGTCATCATGAACCCCCAGCTC TGTGGACTGCTGGTTCTGGGGTCCTGGTGCATCAGTGTCATGGGTTCCCTGCTCGAGACC TTGACTGTTTTGAGGCTGTCCTTCTGCACCGAAATGGAAATTCCACACTTTTTTTGTGAT CTACTTGAAGTCCTGAAGCTCGCCTGTTCTGACACCTTCATTAATAACGTGGTGATATAC TTTGCAACTGGCGTCCTGGGTGTGATTTCCTTCACTGGAATATTTTTCTCTTACTATAAA ATTGTTTTCTCTATACTGAGGATTTCCTCAGCTGGGAGAAAGCACAAAGCGTTTTCCACC TGTGGTTCCCACCTCTCAGTGGTCACCTTGTTCTATGGCACGGGCTTTGGGGTCTATCTC AGTTCTGCAGCCACACCATCTTCTAGGACAAGTCTGGTGGCCTCAGTGATGTACACCATG GTCACCCCCATGCTGAACCCCTTCATCTACAGCCTGAGGAACACGGACATGAAGAGGGCC CTGGGGAGACTCCTCAGTAGGGCAACATTTTTTAATGGTGACATCACTGCAGGACTTTCA |
| Conceptual translation |
METGNQTHAQEFLLLGFSATSEIQFILFGLFLSMYLVTFTGNLLIILAICSDSHLHTPMY FFLSNLSFADLCFTSTTVPKMLLNILTQNKFITYAGCLSQIFFFTSFGCLDNLLLTVMAY DRFVAVCHPLHYTVIMNPQLCGLLVLGSWCISVMGSLLETLTVLRLSFCTEMEIPHFFCD LLEVLKLACSDTFINNVVIYFATGVLGVISFTGIFFSYYKIVFSILRISSAGRKHKAFST CGSHLSVVTLFYGTGFGVYLSSAATPSSRTSLVASVMYTMVTPMLNPFIYSLRNTDMKRA LGRLLSRATFFNGDITAGLS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | C/G | V/L | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 19 | 100 | -100 | SYN | A/G | N/N | 1000GP (YRI) |
| 19 | 14,799,398 | 14,799,398 | NS | C/G | V/L | 1000GP (CEU, CHBJPT) |
| 19 | 14,799,509 | 14,799,509 | NS | A/G | S/P | 1000GP (CEU) |
| 19 | 14,799,626 | 14,799,626 | NS | C/T | E/K | 1000GP (CEU, CHBJPT) |
| 19 | 14,799,628 | 14,799,628 | NS | G/A | T/I | 1000GP (CEU) |
| 19 | 14,799,761 | 14,799,761 | NS | C/T | V/I | 1000GP (CEU, CHBJPT) |
| 19 | 14,799,842 | 14,799,842 | NS | T/C | S/G | 1000GP (CEU) |
| 19 | 14,799,957 | 14,799,957 | SYN | G/A | Y/Y | 1000GP (CHBJPT) |
| 19 | 14,910,210 | 14,910,210 | NS | C/G | V/L | rs73004304 (DbSNP) |
| 19 | 14,910,321 | 14,910,321 | NS | A/G | S/P | rs16979912 (DbSNP) |
| 19 | 14,910,438 | 14,910,438 | NS | C/T | E/K | rs10415312 (DbSNP) |
| 19 | 14,910,440 | 14,910,440 | NS | A/G | I/T | rs62122646 (DbSNP) |
| 19 | 14,910,573 | 14,910,573 | NS | C/T | V/I | rs10415562 (DbSNP) |
| 19 | 14,910,613 | 14,910,613 | SYN | A/G | N/N | rs60788745 (DbSNP) |
| 19 | 14,910,654 | 14,910,654 | NS | C/T | G/S | rs17230134 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L250W | V247L | R233K | S210P | L187F | F177I | E159K | V126I | S99G | F17I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L | V | R | S | L | F | E | I | S | F | 62.29 | 0.064 |
| 2 | L | V | R | S | L | F | E | V | S | F | 16.97 | 0.064 |
| 3 | L | L | R | P | L | F | E | I | G | F | 13.59 | 0.081 |
| 4 | L | V | R | P | L | F | E | I | G | F | 2.23 | 0.064 |
| 5 | L | V | K | P | L | F | K | I | S | F | 1.46 | 0.064 |
| 6 | L | V | R | P | L | F | E | I | S | F | 1.38 | 0.064 |
| 7 | L | L | R | P | L | F | E | I | G | I | 0.92 | 0.081 |
| 8 | L | V | R | P | F | F | E | I | G | F | 0.38 | 0.066 |
| 9 | L | L | R | P | L | F | E | I | S | F | 0.31 | 0.081 |
| 10 | W | V | R | P | F | F | E | I | G | F | 0.15 | 0.066 |
| 11 | L | V | R | S | L | I | E | I | S | F | 0.08 | 0.064 |
| 12 | L | V | R | S | L | F | E | I | G | F | 0.08 | 0.064 |
| 13 | L | L | R | S | L | F | E | V | S | F | 0.08 | 0.081 |
| 14 | L | V | K | P | L | F | E | I | S | F | 0.08 | 0.064 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7A5andOR7C1.aApr07-unspliced | main_exon | 3UTR | chr19 | 14,799,146 | 14,799,177 | - |
| CDS | chr19 | 14,799,177 | 14,800,136 | - | ||
| 5UTR | chr19 | 14,800,136 | 14,800,211 | - | ||