OR7C2 Olfactory Receptor
| Gene Symbol | OR7C21 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | CIT-HSP-87m17, OR19-18, OR19-22, HsOR19.3.11, ORL1029 |
| External Ids | HGNC: 8374 GeneBank: AF399545, BK004213, NM_012377, U86255 ORDB: ORL1029 |
| Build #39 labels | OR7C2 |
| Chromosomal location | 19:14,941,489-14,942,445 (+) |
| Cluster | 19@15a |
| Synteny | CLIC#45 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (rs11883178) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7C1 | 77.81% | 320 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7C1 | 79% | 305 |
| Mouse | Or7c70 | 72% | 319 |
| Rat | Or7c70 | 73% | 317 |
| Cow | OR7C72P | 72% | 316 |
| Orang | OR7C1P | 76% | 318 |
| Horse | OR7D4 | 71% | 310 |
| Chimp | OR7C1 | 78% | 320 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463980 |
| GNF Atlas2 | 208507_at |
Sequence information
| Nucleotide sequence |
ATGGAAAGAGGAAACCAAACAGAAGTTGGAAACTTTCTCCTCCTGGGATTCGCAGAGGAC TCTGACATGCAGCTTCTCCTCCATGGGCTGTTCCTCTCCATGTACCTGGTTACCATCATC GGAAACCTGCTCATCATCCTGACCATCAGTTCAGACTCCCACCTCCACACCCCCATGTAC TTCTTCCTCTCCAACCTGTCCTTTGCTGACATCTGTTTCACATCCACGACTGTCCCAAAG ATGCTGGTGAATATCCAAACACAAAGCAAAATGATCACTTTTGCAGGCTGCCTCACTCAG ATATTTTTTTTCATTGCATTTGGATGCCTGGACAATTTGCTCCTGACCATGACGGCCTAT GACCGCTTCGTGGCCATCTGTTACCCCCTGCACTACACGGTCATCATGAACCCCCGGCTC TGTGGACTGCTGGTTCTGGGGTCCTGGTGCATCAGTGTCATGGGTTCCTTGCTTGAGACC TTGACCATTTTGAGGCTGTCCTTCTGCACAAATATGGAAATTCCGCACTTTTTTTGTGAT CCTTCCGAAGTCCTGAAGCTGGCCTGTTCTGACACCTTCATCAATAACATCGTGATGTAT TTTGTGACCATTGTCCTGGGTGTTTTTCCTCTCTGTGGAATCCTATTCTCTTATTCTCAG ATTTTCTCCTCCGTCCTAAGAGTATCTGCCAGAGGCCAGCACAAAGCCTTTTCCACCTGT GGTTCCCACCTCTCAGTGGTCAGCTTGTTCTATGGCACTGGCCTTGGGGTCTATCTCAGT TCTGCAGTTACACCACCTTCTAGGACAAGTCTGGCAGCCTCGGTGATGTACACCATGGTC ACCCCCATGCTGAACCCCTTCATCTACAGCCTGAGGAACAAGGACATGAAGGGGTCACTG GGGAGACTCCTCCTCAGGGCAACGTCTCTCAAAGAGGGGACCATTGCTAAGCTCTCA |
| Conceptual translation |
MERGNQTEVGNFLLLGFAEDSDMQLLLHGLFLSMYLVTIIGNLLIILTISSDSHLHTPMY FFLSNLSFADICFTSTTVPKMLVNIQTQSKMITFAGCLTQIFFFIAFGCLDNLLLTMTAY DRFVAICYPLHYTVIMNPRLCGLLVLGSWCISVMGSLLETLTILRLSFCTNMEIPHFFCD PSEVLKLACSDTFINNIVMYFVTIVLGVFPLCGILFSYSQIFSSVLRVSARGQHKAFSTC GSHLSVVSLFYGTGLGVYLSSAVTPPSRTSLAASVMYTMVTPMLNPFIYSLRNKDMKGSL GRLLLRATSLKEGTIAKLS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | C/T | T/M | 1000GP (YRI, YRI, YRI) |
| 19 | 100 | -100 | SYN | C/G | L/L | 1000GP (YRI, YRI) |
| 19 | 15,052,323 | 15,052,322 | Ins(1) | -/C | rs34752297 (DbSNP) | |
| 19 | 15,052,653 | 15,052,653 | NS | C/T | T/M | rs8113325 (DbSNP) |
| 19 | 15,052,665 | 15,052,665 | NS | A/G | H/R | rs11883178 (DbSNP) |
| 19 | 15,052,738 | 15,052,737 | Ins(1) | -/G | rs34305437 (DbSNP) | |
| 19 | 15,052,984 | 15,052,983 | Ins(2) | -/AT | rs3044711 (DbSNP) | |
| 19 | 15,052,986 | 15,052,985 | Ins(3) | -/ATC | rs72532311 (DbSNP) | |
| 19 | 15,052,987 | 15,052,986 | Ins(3) | -/ATC | rs56204399 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 19 | 15,045,620 | 15,089,627 | CopyNumber | Variation_35611 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| F94S | T118M | R122H | I221T | K294R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | F | T | R | I | K | 94.55 | 0.254 |
| 2 | F | T | H | I | R | 3.76 | 0.858 |
| 3 | F | M | R | I | R | 0.84 | 0.078 |
| 4 | F | T | R | I | R | 0.38 | 0.254 |
| 5 | S | T | R | I | K | 0.23 | 0.254 |
| 6 | F | T | R | T | K | 0.15 | 0.254 |
| 7 | F | T | H | I | K | 0.08 | 0.858 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7C2.aApr07-unspliced | main_exon | CDS | chr19 | 14,941,489 | 14,942,445 | + |
| 3UTR | chr19 | 14,942,445 | 14,942,448 | + | ||