OR7D2 Olfactory Receptor
| Gene Symbol | OR7D21 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR19-10, OR19-4, HTPCRH03, HsOR19.2.8, ORL34, ORL1027 |
| External Ids | HGNC: 8378 GeneBank: AB065928, AF399537, BK004265, HSHTPRH03 ORDB: ORL34, ORL1027 |
| Build #39 labels | OR7D2 |
| Chromosomal location | 19:9,185,782-9,186,717 (+) |
| Cluster | 19@9b |
| Synteny | CLIC#42 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7A10 | 67.11% | 301 |
| OR7D1P | 68.49% | 311 |
| OR7D4 | 70.74% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7D4 | 71% | 311 |
| Mouse | Or7a36 | 67% | 305 |
| Rat | Or7a36 | 67% | 305 |
| Cow | OR7A79 | 65% | 309 |
| Orang | OR7D4 | 71% | 312 |
| Horse | OR7D4G | 72% | 312 |
| Chimp | OR7D4B | 71% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DA471386 |
| mRNA | AB463981 |
| GNF Atlas2 | gnf1h09473_at |
Sequence information
| Nucleotide sequence |
ATGGAAGCAGGAAACCAAACAGGATTTTTAGAGTTTATCCTTCTCGGACTCTCTGAGGAT CCAGAACTACAGCCGTTCATATTTGGGCTGTTCCTGTCCATGTACCTGGTGACGGTGCTG GGAAACCTGCTCATCATCCTGGCCATCAGCTCTGACTCCCACCTCCACACCCCCATGTAC TTCTTCCTCTCCAACCTGTCCTGGGTTGACATCTGTTTCAGCACTTGCATCGTCCCCAAG ATGCTGGTGAACATCCAGACCGAGAACAAAGCCATCTCCTACATGGACTGCCTCACACAG GTCTATTTCTCCATGTTTTTTCCTATTCTGGACACGCTACTCCTGACCGTGATGGCCTAT GACCGGTTTGTGGCTGTCTGCCACCCTCTGCACTATATGATCATCATGAACCCCCACCTC TGTGGCCTCCTGGTTTTTGTCACCTGGCTCATTGGTGTCATGACATCCCTCCTCCATATT TCTCTGATGATGCATCTAATCTTCTGTAAAGATTTTGAAATTCCACATTTTTTCTGCGAA CTGACGTACATCCTCCAGCTGGCCTGCTCTGATACCTTCCTGAACAGCACGTTGATATAC TTTATGACGGGTGTGCTGGGCGTTTTTCCCCTCCTTGGGATCATTTTCTCTTATTCACGA ATTGCTTCATCCATAAGGAAGATGTCCTCATCTGGGGGAAAACAAAAAGCACTTTCCACC TGTGGGTCTCACCTCTCCGTCGTTTCTTTATTTTATGGGACAGGCATTGGGGTCCACTTC ACTTCTGCGGTGACTCACTCTTCCCAGAAAATCTCCGTGGCCTCGGTGATGTACACTGTG GTCACCCCCATGTTGAACCCCTTCATCTACAGCCTGAGGAACAAGGATGTGAAGGGAGCC CTGGGGAGTCTCCTCAGCAGGGCAGCCTCTTGTTTG |
| Conceptual translation |
MEAGNQTGFLEFILLGLSEDPELQPFIFGLFLSMYLVTVLGNLLIILAISSDSHLHTPMY FFLSNLSWVDICFSTCIVPKMLVNIQTENKAISYMDCLTQVYFSMFFPILDTLLLTVMAY DRFVAVCHPLHYMIIMNPHLCGLLVFVTWLIGVMTSLLHISLMMHLIFCKDFEIPHFFCE LTYILQLACSDTFLNSTLIYFMTGVLGVFPLLGIIFSYSRIASSIRKMSSSGGKQKALST CGSHLSVVSLFYGTGIGVHFTSAVTHSSQKISVASVMYTVVTPMLNPFIYSLRNKDVKGA LGSLLSRAASCL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | G/A | V/I | 1000GP (YRI) |
| 19 | 100 | -100 | SYN | T/C | V/V | 1000GP (YRI, YRI, YRI) |
| 19 | 9,185,988 | 9,185,988 | SYN | T/C | V/V | 1000GP (CEU, CHBJPT) |
| 19 | 9,186,597 | 9,186,597 | SYN | C/G | S/S | 1000GP (CEU) |
| 19 | 9,186,610 | 9,186,610 | NS | A/T | M/L | 1000GP (CHBJPT) |
| 19 | 9,186,705 | 9,186,705 | SYN | A/C | A/A | 1000GP (CEU) |
| 19 | 9,296,664 | 9,296,664 | SYN | C/T | V/V | rs56246934 (DbSNP) |
| 19 | 9,297,047 | 9,297,047 | NS | C/T | T/M | rs13345452 (DbSNP) |
| 19 | 9,297,078 | 9,297,078 | SYN | C/T | G/G | rs61743116 (DbSNP) |
| 19 | 9,297,173 | 9,297,172 | Ins(1) | -/C | rs35299432 (DbSNP) | |
| 19 | 9,297,196 | 9,297,196 | NS | A/G | I/V | rs61739064 (DbSNP) |
| 19 | 9,297,246 | 9,297,246 | SYN | A/G | A/A | rs61732227 (DbSNP) |
| 19 | 9,297,273 | 9,297,273 | SYN | C/G | S/S | rs61732246 (DbSNP) |
| 19 | 9,297,381 | 9,297,381 | SYN | A/C | A/A | rs61733545 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 19 | 9,267,749 | 9,313,321 | CopyNumber | Variation_35700 (DGV) |
| 19 | 9,271,324 | 9,311,170 | CopyNumber | Variation_35701 (DGV) |
| 19 | 9,295,591 | 9,317,125 | CopyNumber | Variation_50243 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T197M | V208I | M277L | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | T | V | M | 95.79 | 0.078 |
| 2 | T | V | L | 2.45 | 0.078 |
| 3 | M | V | M | 1.36 | 0.078 |
| 4 | T | I | M | 0.41 | 0.078 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7D2.aApr07-unspliced | main_exon | 5UTR | chr19 | 9,185,595 | 9,185,782 | + |
| CDS | chr19 | 9,185,782 | 9,186,717 | + | ||
| 3UTR | chr19 | 9,186,717 | 9,188,817 | + | ||