OR7G2 Olfactory Receptor
| Gene Symbol | OR7G21 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | 0.2 (functional) |
| Aliases | OR19-6, OST260, HsOR19.2.4, ORL3771 |
| External Ids | HGNC: 8466 GeneBank: AB065927, AF399539, BK004268, NM_001005193 ORDB: ORL3771 |
| Build #39 labels | OR7G2 |
| Chromosomal location | 19:9,102,272-9,103,243 (-) |
| Cluster | 19@9b |
| Synteny | CLIC#42 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7G1 | 74.35% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7G13 | 76% | 312 |
| Mouse | Or7g34 | 73% | 312 |
| Rat | Or7g34 | 71% | 311 |
| Cow | OR7G8 | 75% | 312 |
| Orang | OR7G2P | 93% | 245 |
| Horse | OR7G49 | 75% | 312 |
| Chimp | OR7G1 | 73% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h03473_at |
Sequence information
| Nucleotide sequence |
ATGGAAGCGAGAAACCAAACAGCTATTTCAAAATTCCTTCTCCTGGGACTGATAGAGGAT CCGGAACTGCAGCCCGTCCTTTTCAGCCTGTTCCTGTCCATGTACTTGGTCACCATCCTG GGGAACCTGCTCATCCTCTTGGCTGTCATCTCTGACTCTCACCTCCACACCCCCATGTAC TTCTTCCTCTCCAATCTCTCCTTTTTGGACATTTGTTTAAGCACAACCACGATCCCAAAG ATGCTGGTGAACATCCAAGCTCAGAATCGGAGCATCACGTACTCAGGCTGCCTCACCCAG ATCTGCTTTGTCTTGTTTTTTGCTGGCTTGGAAAATTGTCTCCTTGCAGCAATGGCCTAT GACCGCTATGTGGCCATTTGTCACCCCCTTAGATACACAGTCATCATGAACCCCCGCCTC TGTGGCCTGCTGATTCTTCTCTCTCTGTTGACTAGTGTTGTGAATGCCCTTCTTCTCAGC CTGATGGTGTTGAGGCTGTCCTTCTGCACAGACCTGGAAATCCCGCTCTTCTTCTGTGAA CTGGCTCAGGTCATCCAACTCACCTGTTCAGACACCCTCATCAATAACATCCTGATATAT TTTGCAGCTTGCATATTTGGTGGTGTTCCTCTGTCTGGAATCATTTTGTCTTACACTCAG ATCACCTCCTGTGTTTTGAGAATGCCATCAGCAAGTGGAAAGCACAAAGCAGTTTCCACC TGTGGGTCTCACCTCTCCATTGTTCTCTTGTTCTATGGGGCAGGTTTGGGGGTGTACATT AGTTCTGTGGTTACTGACTCACCTAGGAAGACTGCAGTGGCTTCAGTGATGTATTCTGTG TTCCCTCAAATGGTGAACCCCTTTATCTATAGTCTGAGGAATAAGGACATGAAAGGAACC TTGAGGAAGTTCATAGGGAGGATACCTTCTCTTCTGTGGTGTGCCATTTGCTTTGGATTC AGGTTTCTAGAG |
| Conceptual translation |
MEARNQTAISKFLLLGLIEDPELQPVLFSLFLSMYLVTILGNLLILLAVISDSHLHTPMY FFLSNLSFLDICLSTTTIPKMLVNIQAQNRSITYSGCLTQICFVLFFAGLENCLLAAMAY DRYVAICHPLRYTVIMNPRLCGLLILLSLLTSVVNALLLSLMVLRLSFCTDLEIPLFFCE LAQVIQLTCSDTLINNILIYFAACIFGGVPLSGIILSYTQITSCVLRMPSASGKHKAVST CGSHLSIVLLFYGAGLGVYISSVVTDSPRKTAVASVMYSVFPQMVNPFIYSLRNKDMKGT LRKFIGRIPSLLWCAICFGFRFLE Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | A/C | F/V | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 19 | 100 | -100 | SYN | T/C | K/K | 1000GP (YRI) |
| 19 | 9,102,350 | 9,102,350 | SYN | T/C | K/K | 1000GP (CEU, CHBJPT) |
| 19 | 9,102,403 | 9,102,403 | NS | A/C | F/V | 1000GP (CEU, CHBJPT) |
| 19 | 9,102,456 | 9,102,456 | NS | A/G | V/A | 1000GP (CEU, CHBJPT) |
| 19 | 9,102,975 | 9,102,975 | NS | C/T | R/Q | 1000GP (CEU, CHBJPT) |
| 19 | 9,213,026 | 9,213,026 | SYN | C/T | K/K | rs4804400 (DbSNP) |
| 19 | 9,213,079 | 9,213,079 | NS | A/C | F/V | rs4804401 (DbSNP) |
| 19 | 9,213,132 | 9,213,132 | NS | A/G | V/A | rs12610094 (DbSNP) |
| 19 | 9,213,182 | 9,213,181 | Ins(1) | -/G | rs35907822 (DbSNP) | |
| 19 | 9,213,396 | 9,213,396 | NS | A/G | L/P | rs7247751 (DbSNP) |
| 19 | 9,213,651 | 9,213,651 | NS | C/T | R/Q | rs62621389 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 192 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| F302V | V284A | A275S | P196L | R111Q | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | F | V | A | P | R | 55.22 | 0.415 |
| 2 | V | A | A | P | R | 35.56 | 0.415 |
| 3 | F | V | A | L | R | 3.46 | 0.415 |
| 4 | F | A | A | P | Q | 3.00 | 0.415 |
| 5 | F | A | A | P | R | 2.15 | 0.415 |
| 6 | V | A | S | P | R | 0.46 | 0.415 |
| 7 | V | V | A | P | R | 0.15 | 0.415 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7G2.aApr07-unspliced | main_exon | 3UTR | chr19 | 9,102,269 | 9,102,272 | - |
| CDS | chr19 | 9,102,272 | 9,103,243 | - | ||
| 5UTR | chr19 | 9,103,243 | 9,103,306 | - | ||