OR8B2 Olfactory Receptor
Gene Symbol | OR8B21 (View this gene in GeneCards) |
Family | 8 |
Subfamily | B |
Pseudogene | No |
CORP pseudogene probability score | 0.83 (pseudogene) |
Aliases | OR11-309, AC002556-C, HsOR11.18.33, ORL3456 |
External Ids | HGNC: 8471 GeneBank: AB065826, AF399508, BC018065, BK004500, NM_001005468 ORDB: ORL3456 |
Build #39 labels | OR8B2 |
Chromosomal location | 11:124,382,405-124,383,343 (-) |
Cluster | 11@124 |
Synteny | CLIC#29 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR8B3 | 97.76% | 313 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR8B3 | 89% | 313 |
Mouse | Or8b3 | 82% | 313 |
Rat | Or8b3c | 83% | 313 |
Rat | Or8b3 | 83% | 313 |
Cow | OR8B3 | 86% | 314 |
Cow | OR8B3G | 85% | 310 |
Orang | OR8B1P | 76% | 307 |
Horse | OR8B3 | 89% | 313 |
Horse | OR8B3H | 88% | 314 |
Chimp | OR8B3 | 97% | 313 |
Expression evidences
Source | Accession |
---|---|
ESTs | DN914774 |
mRNA | BC018065 |
Sequence information
Nucleotide sequence |
ATGCTGGCTAGAAACAACTCCTTAGTGACTGAATTTATTCTTGCTGGATTAACAGATCAT CCAGAGTTCCGGCAACCCCTCTTTTTCCTGTTTCTAGTGATCTACATTGTCACCATGGTA GGCAACCTTGGCTTGATCACTCTTTTCGGTCTAAATTCTCACCTCCACACACCAATGTAC TATTTCCTCTTCAATCTCTCCTTCATTGATCTCTGTTACTCCTCTGTTTTCACTCCCAAA ATGCTAATGAACTTTGTGTCAAAAAAGAATATTATCTCCAATGTTGGGTGCATGACTCGG CTGTTTTTCTTTCTCTTTTTCGTCATCTCTGAATGTTACATGTTGACTTCAATGGCATAT GATCGCTATGTGGCCATCTGTAATCCATTGCTGTATAAGGTCACCATGTCCCATCAGGTC TGTTCTATGCTCACTTTTGCTGCTTACATAATGGGATTGGCTGGAGCCACGGCCCACACC GGGTGCATGCTTAGACTCACCTTCTGCAGTGCTAATATCATCAACCATTACTTGTGTGAC ATACTCCCCCTCCTCCAGCTTTCCTGCACCAGCACCTATGTCAACGAGGTGGTTGTTCTC ATTGTTGTGGGTACTAATATCACGGTACCCAGTTGTACCATCCTCATTTCTTATGTTTTC ATTGTCACTAGCATTCTTCATATCAAATCCACTCAAGGAAGATCAAAAGCCTTCAGTACT TGTAGCTCTCATGTCATTGCTCTGTCTCTGTTTTTTGGGTCAGCGGCATTCATGTATATT AAATATTCTTCTGGATCTATGGAGCAGGGAAAAGTTTCTTCTGTTTTCTACACTAATGTG GTGCCCATGCTCAATCCCCTCATCTACAGTTTGAGGAACAAGGATGTCAAAGTTGCACTG AGGAAAGCTCTGATTAAAATTCAGAGGAGAAATATATTC |
Conceptual translation |
MLARNNSLVTEFILAGLTDHPEFRQPLFFLFLVIYIVTMVGNLGLITLFGLNSHLHTPMY YFLFNLSFIDLCYSSVFTPKMLMNFVSKKNIISNVGCMTRLFFFLFFVISECYMLTSMAY DRYVAICNPLLYKVTMSHQVCSMLTFAAYIMGLAGATAHTGCMLRLTFCSANIINHYLCD ILPLLQLSCTSTYVNEVVVLIVVGTNITVPSCTILISYVFIVTSILHIKSTQGRSKAFST CSSHVIALSLFFGSAAFMYIKYSSGSMEQGKVSSVFYTNVVPMLNPLIYSLRNKDVKVAL RKALIKIQRRNIF Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
11 | 100 | -100 | NS | G/A | L/F | 1000GP (YRI, YRI) |
11 | 100 | -100 | SYN | A/G | F/F | 1000GP (YRI) |
11 | 124,252,382 | 124,252,382 | SYN | A/G | P/P | rs2320232 (DbSNP) |
11 | 124,252,422 | 124,252,422 | NS | A/G | F/S | rs503220 (DbSNP) |
11 | 124,252,617 | 124,252,617 | NS | G/A | T/M | rs470202 (DbSNP) |
11 | 124,252,626 | 124,252,626 | NS | A/G | I/T | rs470625 (DbSNP) |
11 | 124,252,718 | 124,252,718 | SYN | A/G | I/I | rs886201 (DbSNP) |
11 | 124,252,750 | 124,252,750 | NS | A/G | F/L | rs886202 (DbSNP) |
11 | 124,252,892 | 124,252,892 | SYN | A/G | T/T | rs644147 (DbSNP) |
11 | 124,252,898 | 124,252,898 | NS | C/T | M/I | rs73612854 (DbSNP) |
11 | 124,252,904 | 124,252,904 | SYN | G/A | C/C | rs3017589 (DbSNP) |
11 | 124,252,919 | 124,252,919 | SYN | A/G | F/F | rs2320234 (DbSNP) |
11 | 124,252,941 | 124,252,941 | NS | C/T | R/Q | rs71491823 (DbSNP) |
11 | 124,252,960 | 124,252,960 | NS | A/T | Y/N | rs71491824 (DbSNP) |
11 | 124,252,963 | 124,252,963 | NS | A/T | S/T | rs73025504 (DbSNP) |
11 | 124,252,982 | 124,252,982 | SYN | C/T | V/V | rs71491825 (DbSNP) |
11 | 124,253,100 | 124,253,100 | NS | A/G | I/T | rs71491826 (DbSNP) |
11 | 124,253,140 | 124,253,140 | NS | C/T | V/I | rs61911135 (DbSNP) |
11 | 124,253,147 | 124,253,147 | SYN | A/G | F/F | rs530704 (DbSNP) |
11 | 124,253,161 | 124,253,161 | NS | A/G | F/L | rs530740 (DbSNP) |
11 | 124,253,170 | 124,253,170 | NS | A/G | W/R | rs530765 (DbSNP) |
11 | 124,253,181 | 124,253,181 | NS | C/T | R/H | rs28373946 (DbSNP) |
11 | 124,382,996 | 124,382,996 | SYN | A/G | T/T | 1000GP (CEU) |
11 | 124,383,035 | 124,383,035 | SYN | G/A | F/F | 1000GP (CHBJPT) |
11 | 124,383,067 | 124,383,067 | NS | A/T | S/T | 1000GP (CEU) |
11 | 124,383,251 | 124,383,251 | SYN | A/G | F/F | 1000GP (CEU, CHBJPT) |
11 | 124,383,265 | 124,383,265 | NS | G/A | L/F | 1000GP (CEU, CHBJPT) |
11 | 124,383,274 | 124,383,274 | NS | G/A | R/W | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
S93T | T47I | M39T | L27F | R24W | H20R | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|
1 | S | T | M | L | R | H | 46.01 | 0.846 |
2 | S | T | M | L | R | R | 26.50 | 0.846 |
3 | S | T | M | F | W | R | 18.51 | 0.846 |
4 | S | I | M | F | W | R | 3.53 | 0.846 |
5 | S | I | T | L | R | R | 1.92 | 0.846 |
6 | S | I | M | L | R | R | 1.77 | 0.846 |
7 | S | T | M | L | W | R | 1.15 | 0.846 |
8 | T | T | M | F | W | R | 0.31 | 0.846 |
9 | T | T | M | L | R | R | 0.08 | 0.846 |
10 | S | T | T | L | R | R | 0.08 | 0.846 |
11 | T | I | M | F | W | R | 0.08 | 0.846 |
12 | S | I | M | L | W | R | 0.08 | 0.846 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR8B3andOR8B2.aApr07 | main_exon | 3UTR | chr11 | 124,382,402 | 124,382,405 | - |
CDS | chr11 | 124,382,405 | 124,383,343 | - | ||
5UTR | chr11 | 124,383,343 | 124,383,360 | - | ||
exon_5UTR | chr11 | 124,384,374 | 124,384,503 | - | ||
exon_5UTR | chr11 | 124,397,235 | 124,397,368 | - | ||
exon_5UTR | chr11 | 124,398,690 | 124,398,748 | - | ||
exon_5UTR | chr11 | 124,399,609 | 124,399,712 | - | ||
exon_5UTR | chr11 | 124,405,871 | 124,406,002 | - | ||
exon_5UTR | chr11 | 124,406,614 | 124,406,750 | - | ||
exon_5UTR | chr11 | 124,409,650 | 124,409,683 | - |