OR8G5 Olfactory Receptor
| Gene Symbol | OR8G51 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | 0.68 (pseudogene) |
| Aliases | OR11-298, HsOR11.18.25 |
| External Ids | HGNC: 19622 GeneBank: AB065958, BK004516, NM_001005198 |
| Build #39 labels | OR8G5P, OR8G6 |
| Chromosomal location | 11:124,264,932-124,265,864 (+) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| 84.57% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8G6 | 79% | 308 |
| Mouse | Or8g4 | 78% | 307 |
| Rat | Or8g20 | 78% | 311 |
| Cow | OR8G5B | 81% | 311 |
| Orang | OR8G3G | 79% | 308 |
| Horse | OR8G5C | 86% | 311 |
| Chimp | OR8G3P | 76% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136822 |
Sequence information
| Nucleotide sequence |
ATGGCAGCAGAAAACCATTCTTTTGTGACTAAGTTTATTCTGGTTGGGCTAACAGAGAAG TCAGAGCTACAGCTGCCCCTCTTCCTCGTCTTCCTGGGAATCTATGTAGTCACAGTGCTG GGGAACCTGGGCATGATCACACTGATTGGGCTCAGTTCTCACCTGCACACACCTATGTAC TGTTTCCTCAGCAGTCTGTCCTTCATTGACTTCTGCCATTCCACTGTCATTACCCCTAAG ATGCTGGTGAACTTTGTGACAGAGAAGAACATCATCTCCTACCCTGAATGCATGACTCAG CTCTACTTCTTCCTCGTTTTTGCTATTGCAGAGTGTCACATGTTGGCTGCAATGGCATAT GACGGCTACGTGGCCATCTGTAGCCCCTTGCTGTACAGCATCATCATATCCAATAAGGCT TGCTTTTCTCTGATTTTAGTGGTGTATGTAATAGGCCTGATTTGTGCGTCAGCTCATATA GGCTGTATGTTTAGGGTTCAATTCTGCAAATTTGATGTGATCAACCATTATTTCTGTGAT CTTATTTCTATCTTGAAGCTCTCCTGTTCTAGTACTTACATTAATGAGTTACTGATTTTA ATCTTTAGTGGAATTAACATCCTTGTCCCCAGCCTGACCATCCTCAGCTCTTACATCTTC ATCATTGCCAGCATCCTCCGCATTCGCTACACTGAGGGCAGGTCCAAAGCCTTCAGCACT TGCAGCTCCCACATCTCGGCTGTTTCTGTTTTCTTTGGGTCTGCAGCATTCATGTACCTG CAGCCATCATCTGTCAGCTCCATGGACCAGGGGAAAGTGTCCTCTGTGTTTTATACTATT GTTGTGCCCATGCTGAACCCCCTGATCTACAGCCTGAGGAATAAAGATGTCCACGTTGCC CTGAAGAAAACGCTAGGGAAAAGAACATTCTTA |
| Conceptual translation |
MAAENHSFVTKFILVGLTEKSELQLPLFLVFLGIYVVTVLGNLGMITLIGLSSHLHTPMY CFLSSLSFIDFCHSTVITPKMLVNFVTEKNIISYPECMTQLYFFLVFAIAECHMLAAMAY DGYVAICSPLLYSIIISNKACFSLILVVYVIGLICASAHIGCMFRVQFCKFDVINHYFCD LISILKLSCSSTYINELLILIFSGINILVPSLTILSSYIFIIASILRIRYTEGRSKAFST CSSHISAVSVFFGSAAFMYLQPSSVSSMDQGKVSSVFYTIVVPMLNPLIYSLRNKDVHVA LKKTLGKRTFL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | G/E | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | Y/Y | 1000GP (YRI) |
| 11 | 124,134,925 | 124,134,925 | NS | A/G | E/G | rs62622834 (DbSNP) |
| 11 | 124,135,009 | 124,135,009 | NS | G/A | C/Y | rs2512168 (DbSNP) |
| 11 | 124,135,140 | 124,135,140 | NS | C/T | L/F | rs62622835 (DbSNP) |
| 11 | 124,135,215 | 124,135,215 | NS | G/T | V/L | rs11219544 (DbSNP) |
| 11 | 124,135,438 | 124,135,438 | NS | G/A | G/E | rs2512167 (DbSNP) |
| 11 | 124,135,481 | 124,135,481 | SYN | T/C | Y/Y | rs2466701 (DbSNP) |
| 11 | 124,135,662 | 124,135,662 | NS | G/A | A/T | rs2512166 (DbSNP) |
| 11 | 124,135,677 | 124,135,677 | NS | A/G | M/V | rs10893192 (DbSNP) |
| 11 | 124,265,113 | 124,265,113 | NS | G/A | C/Y | 1000GP (CEU, CHBJPT) |
| 11 | 124,265,319 | 124,265,319 | NS | T/G | L/V | 1000GP (CEU) |
| 11 | 124,265,542 | 124,265,542 | NS | G/A | G/E | 1000GP (CEU, CHBJPT) |
| 11 | 124,265,585 | 124,265,585 | SYN | C/T | Y/Y | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G33E | I49T | H56Y | L105F | L130V | A156V | G204E | Y230S | T279A | M284V | A300S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | G | I | H | L | L | A | G | Y | T | M | A | 42.70 | 0.915 |
| 2 | G | I | H | L | L | A | E | Y | T | M | A | 33.49 | 0.915 |
| 3 | G | I | H | L | L | A | E | Y | A | M | A | 10.60 | 0.915 |
| 4 | G | I | H | L | V | A | G | Y | T | V | A | 5.99 | 0.516 |
| 5 | G | I | Y | L | L | A | E | Y | T | M | A | 3.07 | 0.915 |
| 6 | E | I | H | L | L | A | G | Y | T | M | A | 1.92 | 0.915 |
| 7 | G | I | H | L | L | A | E | S | T | M | A | 0.69 | 0.915 |
| 8 | G | I | H | F | L | A | G | Y | T | M | A | 0.38 | 0.915 |
| 9 | G | I | H | L | L | A | E | Y | T | M | S | 0.38 | 0.915 |
| 10 | G | I | H | L | L | A | G | Y | T | V | A | 0.31 | 0.915 |
| 11 | G | I | H | L | V | A | G | Y | T | M | A | 0.15 | 0.516 |
| 12 | G | I | H | F | L | A | E | Y | T | M | A | 0.08 | 0.915 |
| 13 | G | T | H | L | L | A | E | Y | T | M | A | 0.08 | 0.915 |
| 14 | G | I | H | L | L | V | E | Y | T | M | A | 0.08 | 0.915 |
| 15 | E | I | H | L | L | A | G | Y | T | V | A | 0.08 | 0.915 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8G5.aApr07-unspliced | main_exon | 5UTR | chr11 | 124,264,827 | 124,264,932 | + |
| CDS | chr11 | 124,264,932 | 124,265,864 | + | ||
| 3UTR | chr11 | 124,265,864 | 124,265,867 | + | ||