OR8H1 Olfactory Receptor
| Gene Symbol | OR8H11 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR11-180, HsOR11.11.57, ORL3416 |
| External Ids | HGNC: 14824 GeneBank: AB065836, BK004337, NM_001005199 ORDB: ORL3416 |
| Build #39 labels | OR8H1 |
| Chromosomal location | 11:56,290,130-56,291,062 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8H2 | 87.46% | 311 |
| OR8H3 | 89.07% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8H4 | 80% | 311 |
| Mouse | Or8h9 | 74% | 309 |
| Rat | Or8h10 | 74% | 312 |
| Cow | OR8H4P | 75% | 312 |
| Orang | OR5B12P | 52% | 308 |
| Horse | OR8H19P | 73% | 276 |
| Chimp | OR8H1P | 97% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136910 |
Sequence information
| Nucleotide sequence |
ATGGGTAGAAGAAATAACACAAATGTGCCTGACTTCATCCTTACGGGACTGTCAGATTCT GAAGAGGTCCAGATGGCCCTCTTTATACTATTTCTCCTGATATACCTAATTACTATGCTG GGCAATGTGGGGATGATATTGATAATCCGCCTGGACCTCCAGCTTCACACTCCCATGTAT TTTTTCCTTACTCACTTGTCATTTATTGACCTCAGTTACTCAACTGTCATCACACCTAAA ACCTTAGCGAACTTACTGACTTCCAACTATATTTCCTTCATGGGCTGCTTTGCCCAGATG TTCTTTTTTGTCTTCTTGGGAGCTGCTGAATGTTTTCTTCTCTCATCAATGGCCTATGAT CGCTACGTAGCTATCTGCAGTCCTCTACGTTACCCAGTTATTATGTCCAAAAGGCTGTGT TGCGCTCTTGTCACTGGGCCCTATGTGATTAGCTTTATCAACTCCTTTGTCAATGTGGTT TGGATGAGCAGACTGCATTTCTGCGACTCAAATGTAGTTCGTCACTTTTTCTGCGACACG TCTCCAATTTTAGCTCTGTCCTGCATGGACACATACGACATTGAAATCATGATACACATT TTAGCTGGTTCCACCCTGATGGTGTCCCTTATCACAATATCTGCATCCTATGTGTCCATT CTCTCTACCATCCTGAAAATTAATTCCACTTCAGGAAAGCAGAAAGCTTTGTCTACTTGT GCCTCTCATCTCTTGGGAGTCACCATCTTTTATGGAACTATGATTTTTACTTATTTAAAA CCAAGAAAGTCTTATTCTTTGGGAAGGGATCAAGTGGCTTCTGTTTTTTATACTATTGTG ATTCCCATGCTGAATCCACTCATTTATAGTCTTAGAAACAAAGAAGTTAAAAATGCTCTC ATTAGAGTCATGCAGAGAAGACAGGACTCCAGG |
| Conceptual translation |
MGRRNNTNVPDFILTGLSDSEEVQMALFILFLLIYLITMLGNVGMILIIRLDLQLHTPMY FFLTHLSFIDLSYSTVITPKTLANLLTSNYISFMGCFAQMFFFVFLGAAECFLLSSMAYD RYVAICSPLRYPVIMSKRLCCALVTGPYVISFINSFVNVVWMSRLHFCDSNVVRHFFCDT SPILALSCMDTYDIEIMIHILAGSTLMVSLITISASYVSILSTILKINSTSGKQKALSTC ASHLLGVTIFYGTMIFTYLKPRKSYSLGRDQVASVFYTIVIPMLNPLIYSLRNKEVKNAL IRVMQRRQDSR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | R/C | 1000GP (YRI) |
| 11 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI) |
| 11 | 56,057,898 | 56,057,898 | NS | A/G | F/S | rs61888286 (DbSNP) |
| 11 | 56,058,197 | 56,058,197 | SYN | A/G | L/L | rs1842674 (DbSNP) |
| 11 | 56,058,474 | 56,058,474 | NS | A/T | V/E | rs17540861 (DbSNP) |
| 11 | 56,058,535 | 56,058,535 | NS | C/T | G/S | rs11600896 (DbSNP) |
| 11 | 56,290,721 | 56,290,721 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 56,290,998 | 56,290,998 | NS | T/A | E/V | 1000GP (CEU) |
| 11 | 56,291,059 | 56,291,059 | NS | C/T | G/S | 1000GP (CEU, CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 8 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S214F | R130C | L114F | E22V | G2S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | S | R | L | E | G | 84.87 | 0.098 |
| 2 | S | R | L | E | S | 9.06 | 0.098 |
| 3 | F | R | L | V | G | 4.45 | 0.098 |
| 4 | S | C | L | E | G | 0.54 | 0.098 |
| 5 | S | R | L | V | G | 0.38 | 0.098 |
| 6 | F | R | L | E | G | 0.31 | 0.098 |
| 7 | S | R | F | E | G | 0.31 | 0.098 |
| 8 | S | R | F | V | G | 0.08 | 0.098 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8H1.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,290,127 | 56,290,130 | - |
| CDS | chr11 | 56,290,130 | 56,291,062 | - | ||