OR8H2 Olfactory Receptor

Gene Symbol	OR8H2¹ (View this gene in GeneCards)
Family	8
Subfamily	H
Pseudogene	No
CORP pseudogene probability score	0.05 (functional)
Aliases	OR11-171, HsOR11.11.46, ORL3407
External Ids	HGNC: 15308 GeneBank: AB065657, AB065845, BK004341, NM_001005200 ORDB: ORL3407
Build #39 labels	OR8H2
Chromosomal location	11:56,105,043-56,105,978 (+)
Cluster	11@56
Synteny	CLIC#26
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol	Percent	Length
OR8H1	87.46%	311
OR8H3	91.99%	312

Most Similar ORs in other species (Orthologs)

Specie	Symbol	Percent	Length
Dog	OR8H4	77%	311
Mouse	Or8h6	71%	312
Rat	Or8h10	72%	312
Cow	OR8H4P	75%	312
Orang	OR8D4	53%	308
Horse	OR8H1	75%	312
Chimp	OR8H3	93%	312

Expression evidences

Source	Accession
GNF Atlas2	gnf1h10664_at

Sequence information

Nucleotide sequence

ATGATGGGTAGAAGGAATAACACAAATGTGGCTGACTTCATCCTTATGGGACTGACACTT
TCTGAAGAGATCCAGATGGCTCTGTTTATGCTATTTCTCCTGATATACCTAATTACTATG
CTGGGGAATGTGGGGATGATATTGATAATCCGCCTGGACCTCCAGCTTCACACTCCCATG
TATTTTTTCCTTACTCACCTGTCATTTATTGACCTCAGTTACTCAACTGTCGTCACACCT
AAAACCTTAGCGAACTTACTGACTTCCAACTATATTTCCTTTACGGGCTGCTTTGCCCAG
ATGTTCTTTTTTGCCTTCTTGGGTACTGCTGAATGTTACCTTCTCTCCTCAATGGCCCAT
GATCGCTATGCAGCGATCTGCAGTCCTCTACACTACACAGTTATTATGTCCAAAAGGCTC
TGCCTCGCTCTCATCACTGGGCCTTATGTGATTGGCTTTATAGACTCCTTTGTCAACGTG
GTTTCCATGAGCAGATTGCATTTCTACGACTCAAACGTAATTCATCACTTTTTCTGTGAC
ACTTCCCCAATTTTAGCTCTGTCCTGCACTGATACATACAACACCGAAATCCTGATATTC
ATTATTGTTGGTTCCACCCTGATGGTGTCCCTTTTCACAATATCTGCATCCTATGTGTTC
ATTCTCTTTACCATCCTGAAAATTAATTCCACTTCAGGAAAGCAGAAAGCTTTCTCTACT
TGCGTCTCTCATCTCTTGGGAGTCACCATCTTTTATAGCACTCTGATTTTTACTTATTTA
AAACCAAGAAAGTCTTATTCCTTGGGAAGAGATCAAGTGGCTTCTGTTTTTTATACTATT
GTGATTCCCGTGCTGAATCCACTCATTTATAGTCTTAGAAACAAAGAGGTGAAAAATGCT
GTCATCAGAGTCATGCAGAGAAGACAGGACTCCAGG

Conceptual translation

MMGRRNNTNVADFILMGLTLSEEIQMALFMLFLLIYLITMLGNVGMILIIRLDLQLHTPM
YFFLTHLSFIDLSYSTVVTPKTLANLLTSNYISFTGCFAQMFFFAFLGTAECYLLSSMAH
DRYAAICSPLHYTVIMSKRLCLALITGPYVIGFIDSFVNVVSMSRLHFYDSNVIHHFFCD
TSPILALSCTDTYNTEILIFIIVGSTLMVSLFTISASYVFILFTILKINSTSGKQKAFST
CVSHLLGVTIFYSTLIFTYLKPRKSYSLGRDQVASVFYTIVIPVLNPLIYSLRNKEVKNA
VIRVMQRRQDSR

Protein domains and features

Variations - SNPs

Chr	Start	End	Type	Variation	AA Change	SNP IDs
11	100	-100	NS	A/T	R/S	1000GP (YRI, YRI, YRI, YRI)
11	100	-100	SYN	A/G	Q/Q	1000GP (YRI)
11	55,872,537	55,872,537	NS	A/G	N/D	rs61746549 (DbSNP)
11	55,872,620	55,872,620	SYN	C/G	L/L	rs61745328 (DbSNP)
11	55,872,657	55,872,657	NS	A/C	I/L	rs28681529 (DbSNP)
11	55,872,802	55,872,802	NS	C/G	T/R	rs61750935 (DbSNP)
11	55,872,832	55,872,832	NS	C/T	A/V	rs61750923 (DbSNP)
11	55,872,876	55,872,876	NS	C/T	H/Y	rs2512961 (DbSNP)
11	55,872,980	55,872,980	NS	A/G	I/M	rs61734406 (DbSNP)
11	55,872,990	55,872,990	NS	C/G	L/V	rs61734403 (DbSNP)
11	55,873,013	55,873,013	NS	A/T	R/S	rs61734399 (DbSNP)
11	55,873,024	55,873,024	NS	A/G	Y/C	rs2449148 (DbSNP)
11	55,873,026	55,873,026	NS	G/T	D/Y	rs61734396 (DbSNP)
11	55,873,095	55,873,095	NS	G/T	D/Y	rs61745886 (DbSNP)
11	55,873,119	55,873,119	NS	A/G	I/V	rs61734225 (DbSNP)
11	55,873,126	55,873,126	NS	C/T	A/V	rs61734224 (DbSNP)
11	55,873,144	55,873,144	NS	C/T	A/V	rs72919590 (DbSNP)
11	55,873,293	55,873,293	NS	C/T	H/Y	rs61731255 (DbSNP)
11	55,873,334	55,873,334	SYN	A/G	Q/Q	rs11227212 (DbSNP)
11	55,873,368	55,873,368	NS	A/G	M/V	rs1842696 (DbSNP)
11	56,105,356	56,105,356	NS	C/T	A/V	1000GP (CEU)
11	56,105,504	56,105,504	NS	A/G	I/M	1000GP (CEU)
11	56,105,514	56,105,514	NS	G/C	V/L	1000GP (CEU)
11	56,105,548	56,105,548	NS	A/G	Y/C	1000GP (CEU, CHBJPT)
11	56,105,550	56,105,550	NS	G/T	D/Y	1000GP (CEU)
11	56,105,817	56,105,817	NS	T/C	Y/H	1000GP (CEU)
11	56,105,858	56,105,858	SYN	A/G	Q/Q	1000GP (CEU, CHBJPT)

Variations - CNVs

Chr	Start	End	Type	Sources
			CopyNumber	224 (Hasin)
11	54,835,623	55,879,426	CopyNumber	Variation_8690 (DGV)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

	I47L	N90S	T95R	A105V	H120Y	I154M	V158L	R165S	Y169C	D170Y	T206I	V209A	Y259H	P262L	V284M	K295E	% Freq	CORP
1	I	N	T	A	Y	I	V	R	C	D	T	V	Y	P	M	K	69.97	0.098
2	L	N	T	A	Y	I	V	R	C	D	T	V	Y	P	M	K	17.97	0.098
3	I	N	T	V	H	M	L	R	C	Y	T	V	H	P	M	K	3.61	0.098
4	I	N	T	A	Y	I	V	S	C	D	T	V	Y	P	M	K	3.23	0.098
5	I	N	T	A	Y	I	V	R	C	D	T	V	Y	P	M	E	1.08	0.098
6	I	N	T	V	H	I	V	R	C	D	T	V	H	P	M	K	0.84	0.098
7	I	N	R	A	Y	I	V	R	C	D	T	V	Y	P	M	K	0.61	0.098
8	L	N	T	A	Y	I	V	R	C	D	T	A	Y	P	M	K	0.46	0.098
9	L	N	T	A	Y	I	V	R	C	D	T	V	Y	L	M	K	0.38	0.098
10	I	N	T	V	H	I	V	R	C	Y	T	V	H	P	M	K	0.31	0.098
11	I	S	T	A	Y	I	V	R	C	D	T	V	Y	P	M	K	0.23	0.098
12	I	N	T	V	Y	I	V	R	C	D	T	V	Y	P	M	K	0.15	0.098
13	L	N	T	V	Y	I	V	R	C	D	T	V	Y	P	M	K	0.15	0.098
14	I	N	T	A	H	I	V	R	C	D	T	V	Y	P	M	K	0.15	0.098
15	I	N	T	A	H	I	V	R	C	D	T	V	Y	P	V	K	0.15	0.098
16	I	N	T	A	Y	I	V	R	C	D	T	V	Y	P	V	K	0.08	0.098
17	I	N	T	A	Y	I	V	R	C	D	T	V	H	P	M	K	0.08	0.098
18	I	N	T	V	H	I	L	R	C	Y	T	V	H	P	M	K	0.08	0.098
19	I	N	T	V	H	I	L	R	C	Y	I	V	H	P	M	K	0.08	0.098
20	L	N	T	V	H	I	V	R	C	D	T	V	Y	P	M	K	0.08	0.098
21	L	N	T	A	Y	I	V	R	C	D	T	V	Y	P	V	K	0.08	0.098
22	L	N	T	A	H	I	V	R	C	D	T	V	Y	P	M	K	0.08	0.098
23	I	N	T	V	H	I	V	R	C	Y	I	V	H	P	M	K	0.08	0.098
24	I	N	T	V	H	I	L	R	C	Y	T	V	Y	P	M	K	0.08	0.098

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession	Type		Chr	Start	End	Strand
OR8H2.aApr07-unspliced	main_exon	CDS	chr11	56,105,043	56,105,978	+
OR8H2.aApr07-unspliced	main_exon	3UTR	chr11	56,105,978	56,105,981	+

HORDE

Search Olfactory receptors

Select ORs from