OR8H3 Olfactory Receptor
| Gene Symbol | OR8H31 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR11-172, HsOR11.11.47 |
| External Ids | HGNC: 15309 GeneBank: AB065658, AB065840, BK004345, NM_001005201 |
| Build #39 labels | OR8H3 |
| Chromosomal location | 11:56,122,373-56,123,308 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8H1 | 89.07% | 311 |
| OR8H2 | 91.99% | 312 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8H4 | 77% | 311 |
| Mouse | Or8h9 | 72% | 310 |
| Rat | Or8h10 | 73% | 312 |
| Cow | OR8H4P | 73% | 312 |
| Orang | OR5B12P | 52% | 308 |
| Horse | OR8H1 | 76% | 312 |
| Chimp | OR8H2 | 93% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h10665_at |
Sequence information
| Nucleotide sequence |
ATGATGGGTAGAAGGAATGACACAAATGTGGCTGACTTCATCCTTACGGGACTGTCAGAC TCTGAAGAGGTCCAGATGGCTCTGTTTATGCTATTTCTCCTCATATACCTAATTACTATG CTGGGGAATGTGGGGATGCTATTGATAATCCGCCTGGACCTCCAGCTTCACACTCCCATG TATTTTTTCCTTACTCACCTGTCATTTATTGACCTCAGTTACTCAACTGTCGTCACACCT AAAACCTTAGCGAACTTACTGACTTCCAACTATATTTCCTTCACGGGCTGCTTTGCCCAG ATGTTCTGTTTTGTCTTCTTGGGTACTGCTGAATGTTATCTTCTCTCCTCAATGGCCTAT GATCGCTATGCAGCGATCTGCAGTCCTCTACACTACACAGTTATTATGCCCAAAAGGCTC TGCCTCGCTCTCATCACTGGGCCTTATGTGATTGGCTTTATGGACTCCTTTGTCAATGTG GTTTCCATGAGCAGATTGCATTTCTGTGACTCAAACATAATTCATCACTTTTTCTGTGAC ACTTCCCCAATTTTAGCTCTGTCCTGCACTGACACAGACAACACTGAAATGCTGATATTC ATTATCGCTGGTTCCACCCTGATGGTGTCCCTTATCACAATATCTGCATCCTATGTGTCC ATTCTCTCTACCATCCTGAAAATTAATTCCACTTCAGGAAAGCAGAAAGCTTTCTCTACT TGCGTCTCTCATCTCTTGGGAGTCACCATCTTCTATGGAACTATGATTTTTACTTACTTA AAGCCAAGAAAGTCTTATTCCTTGGGAAGAGATCAAGTGGCTCCTGTGTTTTATACTATT GTGATTCCCATGCTGAATCCACTCATTTATAGTCTTAGAAACAGAGAAGTGAAAAATGCT CTCATTAGAGTCATGCAGAGAAGACAGGACTCCAGG |
| Conceptual translation |
MMGRRNDTNVADFILTGLSDSEEVQMALFMLFLLIYLITMLGNVGMLLIIRLDLQLHTPM YFFLTHLSFIDLSYSTVVTPKTLANLLTSNYISFTGCFAQMFCFVFLGTAECYLLSSMAY DRYAAICSPLHYTVIMPKRLCLALITGPYVIGFMDSFVNVVSMSRLHFCDSNIIHHFFCD TSPILALSCTDTDNTEMLIFIIAGSTLMVSLITISASYVSILSTILKINSTSGKQKAFST CVSHLLGVTIFYGTMIFTYLKPRKSYSLGRDQVAPVFYTIVIPMLNPLIYSLRNREVKNA LIRVMQRRQDSR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | C/T | T/M | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | A/G | Q/Q | 1000GP (YRI) |
| 11 | 55,889,895 | 55,889,895 | NS | C/T | T/M | rs61751933 (DbSNP) |
| 11 | 55,889,987 | 55,889,987 | NS | A/C | I/L | rs7107077 (DbSNP) |
| 11 | 55,890,156 | 55,890,156 | NS | G/T | C/F | rs61746202 (DbSNP) |
| 11 | 55,890,257 | 55,890,257 | NS | C/T | P/S | rs1842691 (DbSNP) |
| 11 | 55,890,273 | 55,890,273 | NS | C/T | P/L | rs61743852 (DbSNP) |
| 11 | 55,890,297 | 55,890,297 | NS | G/T | G/V | rs61743843 (DbSNP) |
| 11 | 55,890,320 | 55,890,320 | NS | C/G | L/V | rs61743838 (DbSNP) |
| 11 | 55,890,356 | 55,890,356 | NS | G/T | D/Y | rs61746318 (DbSNP) |
| 11 | 55,890,449 | 55,890,449 | NS | A/G | I/V | rs17531522 (DbSNP) |
| 11 | 55,890,571 | 55,890,571 | SYN | C/T | C/C | rs61743017 (DbSNP) |
| 11 | 55,890,609 | 55,890,609 | NS | C/T | T/I | rs61743026 (DbSNP) |
| 11 | 55,890,611 | 55,890,611 | NS | A/G | M/V | rs61743031 (DbSNP) |
| 11 | 55,890,664 | 55,890,664 | SYN | A/G | Q/Q | rs61745899 (DbSNP) |
| 11 | 55,890,726 | 55,890,726 | NS | G/T | R/I | rs61747871 (DbSNP) |
| 11 | 55,890,732 | 55,890,732 | NS | A/G | K/R | rs11606538 (DbSNP) |
| 11 | 55,890,736 | 55,890,736 | SYN | A/G | E/E | rs11604579 (DbSNP) |
| 11 | 56,122,419 | 56,122,419 | NS | C/T | T/M | 1000GP (CEU, CHBJPT) |
| 11 | 56,122,657 | 56,122,657 | SYN | G/A | T/T | 1000GP (CHBJPT) |
| 11 | 56,122,680 | 56,122,680 | NS | G/T | C/F | 1000GP (CEU) |
| 11 | 56,122,844 | 56,122,844 | NS | G/C | V/L | 1000GP (CEU) |
| 11 | 56,122,879 | 56,122,879 | SYN | T/C | C/C | 1000GP (CEU) |
| 11 | 56,122,880 | 56,122,880 | NS | G/T | D/Y | 1000GP (CEU) |
| 11 | 56,122,973 | 56,122,973 | NS | A/G | I/V | 1000GP (CEU) |
| 11 | 56,123,133 | 56,123,133 | NS | C/T | T/I | 1000GP (CEU) |
| 11 | 56,123,256 | 56,123,256 | NS | G/A | R/K | 1000GP (CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 170 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T16M | L47I | C103F | P137S | L142P | V158L | I201V | T254I | M255V | R293I | R295K | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | T | L | C | S | L | V | I | T | M | R | R | 75.50 | 0.098 |
| 2 | M | L | C | S | L | V | I | T | M | R | R | 10.06 | 0.098 |
| 3 | T | I | C | S | L | V | I | T | M | R | R | 5.53 | 0.098 |
| 4 | T | L | F | S | P | L | V | I | M | I | R | 3.92 | 0.144 |
| 5 | T | L | C | S | L | V | I | T | M | R | K | 2.46 | 0.098 |
| 6 | T | L | C | S | L | V | I | T | V | R | R | 0.61 | 0.098 |
| 7 | T | L | F | S | L | L | V | I | M | I | R | 0.38 | 0.144 |
| 8 | T | L | C | S | P | L | V | I | M | I | R | 0.31 | 0.144 |
| 9 | T | I | C | S | L | V | I | T | M | R | K | 0.23 | 0.098 |
| 10 | T | L | C | P | L | V | I | T | M | R | R | 0.15 | 0.098 |
| 11 | M | L | F | S | L | V | I | T | M | R | R | 0.15 | 0.098 |
| 12 | T | L | F | S | L | V | I | T | M | R | R | 0.15 | 0.098 |
| 13 | T | L | F | S | P | V | V | I | M | I | R | 0.08 | 0.144 |
| 14 | T | L | C | S | L | L | I | T | M | R | R | 0.08 | 0.098 |
| 15 | T | L | F | P | P | L | V | I | M | I | R | 0.08 | 0.144 |
| 16 | T | L | C | S | L | L | V | T | M | R | R | 0.08 | 0.098 |
| 17 | T | L | C | S | P | L | V | T | M | R | R | 0.08 | 0.098 |
| 18 | T | L | F | S | L | L | V | I | M | R | R | 0.08 | 0.144 |
| 19 | T | L | F | S | P | L | V | I | M | I | K | 0.08 | 0.144 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8H3.aApr07-unspliced | main_exon | CDS | chr11 | 56,122,373 | 56,123,308 | + |
| 3UTR | chr11 | 56,123,308 | 56,123,311 | + | ||