OR8I2 Olfactory Receptor
| Gene Symbol | OR8I21 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | I |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR11-170, HsOR11.11.45, ORL3409 |
| External Ids | HGNC: 15310 GeneBank: AB065656, AB065844, AF399513, BK004342, NM_001003750 ORDB: ORL3409 |
| Build #39 labels | OR8I2 |
| Chromosomal location | 11:56,093,308-56,094,237 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8I1P | 82.2% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8I2P | 90% | 308 |
| Mouse | Or8i2 | 86% | 307 |
| Rat | Or8i2 | 86% | 309 |
| Cow | OR8I15P | 78% | 310 |
| Orang | OR8A1 | 55% | 297 |
| Horse | OR8I16P | 73% | 310 |
| Chimp | OR8I1P | 83% | 307 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137008 |
Sequence information
| Nucleotide sequence |
ATGGCTGGCAACAATTTCACTGAGGTTACCGTCTTCATCCTCTCTGGATTTGCAAATCAC CCTGAATTACAAGTCAGTCTTTTCTTGATGTTTCTCTTCATTTATCTATTCACTGTTTTG GGAAACCTGGGACTGATCACGTTAATCAGAATGGATTCTCAGCTTCACACCCCTATGTAC TTTTTCCTGAGCAATTTAGCATTTATTGACATATTTTACTCCTCTACTGTAACACCTAAG GCATTGGTGAATTTCCAATCCAATCGGAGATCCATCTCCTTTGTTGGCTGCTTTGTTCAA ATGTACTTTTTTGTTGGATTGGTGTGTTGTGAGTGTTTCCTTCTGGGATCAATGGCCTAC AATCGCTACATAGCAATCTGCAATCCCTTACTGTATTCAGTAGTCATGTCCCAAAAAGTG TCCAACTGGCTGGGAGTAATGCCATATGTGATAGGCTTCACAAGCTCGCTGATATCTGTC TGGGTGATAAGCAGTTTGGCGTTCTGTGATTCCAGCATCAATCATTTTTTTTGTGACACC ACAGCTCTTTTAGCACTCTCCTGTGTAGATACATTCGGCACAGAAATGGTGAGCTTTGTC TTAGCTGGATTCACTCTTCTTAGCTCTCTCCTTATCATCACAGTCACTTATATCATCATC ATCTCAGCCATCCTGAGGATCCAGTCAGCAGCAGGCAGGCAGAAGGCCTTCTCCACCTGC GCATCCCACCTCATGGCTGTAACTATCTTTTATGGGTCTCTGATTTTCACCTATTTGCAA CCTGATAACACATCATCGCTGACCCAGGCGCAGGTGGCATCTGTATTCTATACGATTGTC ATTCCCATGCTGAATCCACTCATCTACAGTCTGAGGAACAAAGATGTGAAAAATGCTCTT CTGAGAGTCATACATAGAAAACTTTTTCCA |
| Conceptual translation |
MAGNNFTEVTVFILSGFANHPELQVSLFLMFLFIYLFTVLGNLGLITLIRMDSQLHTPMY FFLSNLAFIDIFYSSTVTPKALVNFQSNRRSISFVGCFVQMYFFVGLVCCECFLLGSMAY NRYIAICNPLLYSVVMSQKVSNWLGVMPYVIGFTSSLISVWVISSLAFCDSSINHFFCDT TALLALSCVDTFGTEMVSFVLAGFTLLSSLLIITVTYIIIISAILRIQSAAGRQKAFSTC ASHLMAVTIFYGSLIFTYLQPDNTSSLTQAQVASVFYTIVIPMLNPLIYSLRNKDVKNAL LRVIHRKLFP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | A/T | K/N | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/A | S/S | 1000GP (YRI) |
| 11 | 55,861,153 | 55,861,153 | NS | A/G | I/V | rs17603011 (DbSNP) |
| 11 | 55,861,200 | 55,861,200 | NS | A/T | K/N | rs17150021 (DbSNP) |
| 11 | 55,861,484 | 55,861,484 | NS | A/C | Q/P | rs61887096 (DbSNP) |
| 11 | 55,861,650 | 55,861,650 | nonsense SNP | C/G | Y/* | rs61887097 (DbSNP) |
| 11 | 56,093,677 | 56,093,677 | NS | A/G | I/V | 1000GP (CEU) |
| 11 | 56,093,821 | 56,093,821 | NS | A/G | S/G | 1000GP (CEU) |
| 11 | 56,093,831 | 56,093,831 | NS | A/T | H/L | 1000GP (CEU) |
| 11 | 56,094,008 | 56,094,008 | NS | A/C | Q/P | 1000GP (CEU) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| C110S | I124V | K139N | Q234P | S266L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | C | I | K | Q | S | 90.32 | 1.000 |
| 2 | C | V | K | P | S | 4.30 | 1.000 |
| 3 | C | I | N | Q | S | 4.07 | 1.000 |
| 4 | S | I | K | Q | S | 0.46 | 1.000 |
| 5 | C | V | K | Q | S | 0.46 | 1.000 |
| 6 | C | V | K | P | L | 0.31 | 1.000 |
| 7 | C | I | K | Q | L | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8I2.aApr07-unspliced | main_exon | CDS | chr11 | 56,093,308 | 56,094,237 | + |
| 3UTR | chr11 | 56,094,237 | 56,094,240 | + | ||