OR8K5 Olfactory Receptor
| Gene Symbol | OR8K51 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.07 (functional) |
| Aliases | OR11-174, HsOR11.11.49, ORL3330 |
| External Ids | HGNC: 15315 GeneBank: AB065542, BK004347, NM_001004058 ORDB: ORL3330 |
| Build #39 labels | OR8K5 |
| Chromosomal location | 11:56,159,397-56,160,317 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8K3 | 70.03% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8K87 | 70% | 307 |
| Mouse | Or8k20 | 76% | 307 |
| Rat | Or8k16b | 77% | 307 |
| Cow | OR8K5B | 82% | 294 |
| Orang | OR5E1P | 52% | 308 |
| Horse | OR8K72 | 71% | 307 |
| Chimp | OR8K5P | 98% | 287 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h10676_at |
Sequence information
| Nucleotide sequence |
ATGGGCCAACACAATCTAACAGTGCTAACTGAATTCATTCTGATGGAACTCACAAGGCGG CCTGAGCTGCAGATTCCCCTTTTTGGAGTCTTCCTCGTCATCTACCTAATCACAGTGGTG GGCAACCTAACTATGATCATTTTGACCAAACTGGACTCCCACTTACATACACCTATGTAC TTTTCTATCAGACATTTGGCTTTTGTTGATCTTGGTAATTCTACTGTCATTTGTCCCAAG GTGCTGGCAAATTTTGTTGTGGATCGAAATACTATTTCCTATTATGCATGTGCTGCACAG CTGGCATTCTTCCTTATGTTCATTATCAGTGAATTTTTCATCCTGTCAGCCATGGCCTAT GACCGCTATGTGGCCATTTGTAACCCTCTGCTCTATTATGTTATTATGTCTCAGCGACTG TGTCATGTACTGGTGGGCATTCAATATCTCTACAGCACATTTCAGGCTCTGATGTTCACT ATTAAGATTTTTACATTGACCTTCTGTGGCTCTAATGTCATCAGTCATTTTTACTGTGAT GATGTTCCTTTGCTACCTATGCTTTGCTCAAATGCACAGGAAATAGAATTGTTGAGCATA CTATTTTCTGTATTTAATTTGATCTCCTCCTTTCTGATAGTCTTAGTGTCCTACATGTTG ATTTTGTTAGCTATATGTCAAATGCATTCTGCAGAGGGCAGGAAAAAGGCTTTCTCCACA TGTGGTTCCCATTTGACAGTGGTGGTTGTGTTCTATGGGTCTCTACTCTTCATGTACATG CAGCCCAATTCCACTCACTTCTTTGATACTGATAAAATGGCTTCTGTGTTTTACACTTTA GTAATCCCCATGCTTAACCCTTTGATTTACAGCTTAAGAAACGAAGAGGTGAAAAATGCC TTCTATAAGCTCTTTGAGAAT |
| Conceptual translation |
MGQHNLTVLTEFILMELTRRPELQIPLFGVFLVIYLITVVGNLTMIILTKLDSHLHTPMY FSIRHLAFVDLGNSTVICPKVLANFVVDRNTISYYACAAQLAFFLMFIISEFFILSAMAY DRYVAICNPLLYYVIMSQRLCHVLVGIQYLYSTFQALMFTIKIFTLTFCGSNVISHFYCD DVPLLPMLCSNAQEIELLSILFSVFNLISSFLIVLVSYMLILLAICQMHSAEGRKKAFST CGSHLTVVVVFYGSLLFMYMQPNSTHFFDTDKMASVFYTLVIPMLNPLIYSLRNEEVKNA FYKLFEN Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | M/V | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | SYN | G/A | T/T | 1000GP (YRI) |
| 11 | 55,926,999 | 55,926,999 | SYN | G/A | T/T | rs61746296 (DbSNP) |
| 11 | 55,927,442 | 55,927,442 | NS | T/C | M/V | rs61746523 (DbSNP) |
| 11 | 55,927,591 | 55,927,591 | NS | A/G | F/S | rs2512938 (DbSNP) |
| 11 | 56,159,966 | 56,159,966 | NS | T/C | M/V | 1000GP (CEU) |
| 11 | 56,160,287 | 56,160,287 | NS | C/T | E/K | 1000GP (CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 243 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| D121E | M118V | D70E | F68S | R20W | E11K | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | D | M | D | F | R | E | 88.56 | 0.198 |
| 2 | D | V | D | F | R | E | 4.84 | 0.498 |
| 3 | D | M | D | F | R | K | 3.76 | 0.198 |
| 4 | D | M | D | S | R | E | 2.23 | 0.198 |
| 5 | E | M | D | F | R | E | 0.31 | 1.000 |
| 6 | D | M | E | F | R | E | 0.15 | 0.198 |
| 7 | D | M | D | F | W | E | 0.15 | 0.198 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8K5.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,159,394 | 56,159,397 | - |
| CDS | chr11 | 56,159,397 | 56,160,317 | - | ||