Protein information for: OR2L8



MENYNQTSTDFILLGLFPPSRIDLFFFILIVFIFLMALIGNLSMILLIFL
DTHLHTPMYFLLSQLSLIDLNYISTIVPKMASDFLHGNKSISFTGCGIQS
FFFLALGGAEALLLASMAYDRYIAICFPLHYLIRMSKRVCVLMITGSWII
GSINACAHTVYVLHIPYCRSRAINHFFCDVPAMVTLACMDTWVYEGTVFL
SATIFLVFPFIGISCSYGQVLFAVYHMKSAEGRKKAYLTCSTHLTVVTFY
YAPFVYTYLRPRSLRSPTEDKVLAVFYTILTPMLNPIIYSLRNKEVMGAL
TRVSQRICSVKM
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 23 49 DLFFFILIVFIFLMALIGNLSMILLIF
TM2 60 82 FLLSQLSLIDLNYISTIVPKMAS
TM3 97 117 GIQSFFFLALGGAEALLLASM
TM4 140 160 CVLMITGSWIIGSINACAHTV
TM5 197 218 TVFLSATIFLVFPFIGISCSYG
TM6 240 264 CSTHLTVVTFYYAPFVYTYLRPRSL
TM7 270 289 DKVLAVFYTILTPMLNPIIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
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