Protein information for: OR3A2
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.
Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)
Sequences of the TM regions:
|TM1 ||27 ||53 ||QPVVFVLLLFAYLVTTGGNLSILAAVL |
|TM2 ||64 ||86 ||FFLGNLSVLDVGCITVTVPAMLG |
|TM3 ||101 ||121 ||LSQLFFFHLLAGMDCFLLTAM |
|TM4 ||144 ||164 ||QRMLVAASLACAFTNALTHTV |
|TM5 ||201 ||222 ||LLFAVGFIMAGTPLVLIITAYS |
|TM6 ||244 ||268 ||CGSHLTVVCLFFGRGIFNYMRLGSE |
|TM7 ||274 ||293 ||DKGVGVFNTVINPMLNPLIY |
The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.