Protein information for: OR4A8P



MRQNNNITEFVLLGFSQYPDVQNALFVMFLLIYIVTMVGNLLIVVSIIAS
PFLGSPVYFFLACLSFIDAVYSTTISPVLIVDLLCDKKTISFPACMGQLF
IEHLFGDTDVFLLVVMAYDRYVATCKPLRYLTIMNXQVCILLLVVAVTGG
FLHSVFQILVVYSLPFCGPNVIYHFFCNIYPLLDLECTDTYFVGLAVVFN
GGAICMVIFTLLLISYGVILNSLKTYSPEGRHKAPFICSSHFIMVILFFV
PCIFLYVRPVSNFPIDKFLTVFYSVITPKLNPFIYMLRNSEMRNAIENLL
GYQSGKTGFRCSKLN
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 22 48 QNALFVMFLLIYIVTMVGNLLIVVSII
TM2 59 81 FFLACLSFIDAVYSTTISPVLIV
TM3 96 116 MGQLFIEHLFGDTDVFLLVVM
TM4 139 159 CILLLVVAVTGGFLHSVFQIL
TM5 196 217 AVVFNGGAICMVIFTLLLISYG
TM6 238 262 CSSHFIMVILFFVPCIFLYVRPVSN
TM7 267 284 FLTVFYSVITPKLNPFIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
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