Protein information for: OR4D2



METGNLTWVSDFVFLGLSQTRELQRFLFLMFLFVYITTVMGNILIIITVT
SDSQLHTPMYFLLRNLAVLDLCFSSVTAPKMLVDLLSEKKTISYQGCMGQ
IFFFHFLGGAMVFFLSVMAFDRLIAISRPLRYVTVMNTQLWVGLVVATWV
GGFVHSIVQLALMLPLPFCGPNILDNFYCDVPQVLRLACTDTSLLEFLKI
SNSGLLDVVWFFLLLMSYLFILVMLRSHPGEARRKAASTCTTHIIVVSMI
FVPSIYLYARPFTPFPMDKLVSIGHTVMTPMLNPMIYTLRNQDMQAAVRR
LGRHRLV
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 24 50 QRFLFLMFLFVYITTVMGNILIIITVT
TM2 61 83 FLLRNLAVLDLCFSSVTAPKMLV
TM3 98 118 MGQIFFFHFLGGAMVFFLSVM
TM4 141 161 WVGLVVATWVGGFVHSIVQLA
TM5 198 219 LKISNSGLLDVVWFFLLLMSYL
TM6 240 264 CTTHIIVVSMIFVPSIYLYARPFTP
TM7 269 286 LVSIGHTVMTPMLNPMIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
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