Protein information for: OR4E2



MDSLNQTRVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATV
FTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQ
LFFLHLFACAEIFLLIIVAYDRYVAICTPLHYPNVMNMRVCIQLVFALWL
GGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIV
TNSGTISLSCFLAVVTSYMVILVSLRKHSAEGRQKALSTCSAHFMVVALF
FGPCIFIYTRPDTSFSIDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQ
LRQRQVFFTKSYT
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 24 50 EMLFFMAFSAIYMLTLSGNILIIIATV
TM2 61 83 FFLSNLSFIDICHSSVTVPKMLE
TM3 98 118 ITQLFFLHLFACAEIFLLIIV
TM4 141 161 CIQLVFALWLGGTVHSLGQTF
TM5 198 219 LIVTNSGTISLSCFLAVVTSYM
TM6 240 264 CSAHFMVVALFFGPCIFIYTRPDTS
TM7 269 286 VVSVFYTVVTPLLNPFIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
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