Protein information for: OR52E8



MSTSNHTQFHPSSFLLLGIPGLEDVHIWIGVPFFFVYLVALLGNTALLFV
IQTEQSLHEPMYYFLAMLDSIDLGLSTATIPKMLGIFWFNTKEISFGGCL
SHMFFIHFFTAMESIVLVAMAFDRYIAICKPLRYTMILTSKIISLIAGIA
VLRSLYMVVPLVFLLLRLPFCGHRIIPHTYCEHMGIARLACASIKVNIRF
GLGNISLLLLDVILIILSYVRILYAVFCLPSWEARLKALNTCGSHIGVIL
AFFTPAFFSFLTHRFGHNIPQYIHIILANLYVVVPPALNPVIYGVRTKQI
RERVLRIFLKTNH
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 26 52 HIWIGVPFFFVYLVALLGNTALLFVIQ
TM2 63 85 YFLAMLDSIDLGLSTATIPKMLG
TM3 100 120 LSHMFFIHFFTAMESIVLVAM
TM4 143 163 ISLIAGIAVLRSLYMVVPLVF
TM5 200 220 FGLGNISLLLLDVILIILSYV
TM6 242 266 CGSHIGVILAFFTPAFFSFLTHRFG
TM7 274 293 HIILANLYVVVPPALNPVIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
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