Protein information for: OR5M12P



MKIDPKCNGTEVTEFILLGLTSQPELQPMLFVVFLLIYLITLTGKFGMIF
LIRFTPQLQTHMYFFLTHLACVDIFYSTNVSPRELVNFLSEKKTISYAGC
LAQCFVFVTLLLTEYYMLGAMAYDCYMAICNPLHYSSKMSRAVCICLVTF
PYFWGSMVGTMQVILTSRLSFFGPNTINHFYCTDPPLLMLTSSDTYIKQT
ALFVSAGINLTVSLLIILISYIFIFITIMRIRSSEGQLKAFSTCGSHLTA
VTMFYGSLFCMYLRPTNELSVEQGKMGVVFCIFVSPMLNPFIYRLRNKDV
KQALKRVFMRNLGKTKKNSVTTV
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 27 53 QPMLFVVFLLIYLITLTGKFGMIFLIR
TM2 64 86 FFLTHLACVDIFYSTNVSPRELV
TM3 101 121 LAQCFVFVTLLLTEYYMLGAM
TM4 144 164 CICLVTFPYFWGSMVGTMQVI
TM5 201 222 ALFVSAGINLTVSLLIILISYI
TM6 244 268 CGSHLTAVTMFYGSLFCMYLRPTNE
TM7 274 293 GKMGVVFCIFVSPMLNPFIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
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