Protein information for: OR8B12



MAAKNSSVTEFILEGLTHQPGLRIPLFFLFLGFYTVTVVGNLGLITLIGL
NSHLHTPMYFFLFNLSLIDFCFSTTITPKMLMSFVSRKNIISFTGCMTQL
FFFCFFVVSESFILSAMAYDRYVAICNPLLYTVTMSCQVCLLLLLGAYGM
GFAGAMAHTGSIMNLTFCADNLVNHFMCDILPLLELSCNSSYMNELVVFI
VVAVDVGMPIVTVFISYALILSSILHNSSTEGRSKAFSTCSSHIIVVSLF
FGSGAFMYLKPLSILPLEQGKVSSLFYTIIVPVLNPLIYSLRNKDVKVAL
RRTLGRKIFS
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 23 49 RIPLFFLFLGFYTVTVVGNLGLITLIG
TM2 60 82 FFLFNLSLIDFCFSTTITPKMLM
TM3 97 117 MTQLFFFCFFVVSESFILSAM
TM4 140 160 CLLLLLGAYGMGFAGAMAHTG
TM5 197 218 VVFIVVAVDVGMPIVTVFISYA
TM6 240 264 CSSHIIVVSLFFGSGAFMYLKPLSI
TM7 270 289 GKVSSLFYTIIVPVLNPLIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
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