Protein information for: OR8I2



MAGNNFTEVTVFILSGFANHPELQVSLFLMFLFIYLFTVLGNLGLITLIR
MDSQLHTPMYFFLSNLAFIDIFYSSTVTPKALVNFQSNRRSISFVGCFVQ
MYFFVGLVCCECFLLGSMAYNRYIAICNPLLYSVVMSQKVSNWLGVMPYV
IGFTSSLISVWVISSLAFCDSSINHFFCDTTALLALSCVDTFGTEMVSFV
LAGFTLLSSLLIITVTYIIIISAILRIQSAAGRQKAFSTCASHLMAVTIF
YGSLIFTYLQPDNTSSLTQAQVASVFYTIVIPMLNPLIYSLRNKDVKNAL
LRVIHRKLFP
In red: predicted N-glycosylation site.
In magenta: Conserved cysteines that are predicted to form a disulfide bond.
Underlined and bold: TM regions.

Predicted binding site residues (CDRs) are highlighted according to the following amino acid color code:
| | basic (H,R,K)
| | hydrophilic, no charge (Q,N,T,S)
| | aliphatic (M,A,I,L,V)
| | aromatic (F,Y,W)
| | helix breakers (G,P)
| | acidic (D,E)
| | cysteine (C)

Sequences of the TM regions:

TM

Start position

End position

Sequence

TM1 24 50 QVSLFLMFLFIYLFTVLGNLGLITLIR
TM2 61 83 FFLSNLAFIDIFYSSTVTPKALV
TM3 98 118 FVQMYFFVGLVCCECFLLGSM
TM4 141 161 SNWLGVMPYVIGFTSSLISVW
TM5 197 218 VSFVLAGFTLLSSLLIITVTYI
TM6 240 264 CASHLMAVTIFYGSLIFTYLQPDNT
TM7 270 289 AQVASVFYTIVIPMLNPLIY

The information was derived from a multiple alignment of ORs, based on the algorithms of Man et al. Protein Sci. 2004 Jan;13(1):240-54.
HORDE homepage