Search Olfactory receptors

(e.g. OR1G1, AF087928, Segregating Pseudo)

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OR10A4 Olfactory Receptor

Gene Symbol OR10A41 (View this gene in GeneCards)
Family 10
Subfamily A
Pseudogene No
CORP pseudogene probability score 0.03 (functional)
Aliases OR11-78, OR11-87, JCG5, HsOR11.4.6, ORL356
External Ids HGNC: 15130   GeneBank: AF209506, AF399625, BK004201, BK004564, NM_207186   ORDB: ORL356   
Build #39 labels OR10A4P
Chromosomal location 11:6,876,621-6,877,592 (+)
Cluster 11@7
Synteny CLIC#24
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol Percent Length
OR10A5 75.49% 306

Most Similar ORs in other species (Orthologs)

Specie Symbol Percent Length
Dog OR10A4 89% 324
Chimp CONTIG*********** 75% 310
Mouse Or10a4 88% 317
Rat Or10a4 87% 315
Cow OR10U1 54% 309

Expression evidences

Source Accession
mRNA AF209506
GNF Atlas2 gnf1h08194_at

Sequence information

Nucleotide sequence ATGCCCAGTGAAGTCCTGGGCAGAAGAATGATGTGGGAAAACTGGACAATTGTCAGTGAA
TTTGTTCTCGTGAGCTTCTCAGCCCTGTCCACTGAGCTTCAGGCTCTACTGTTTCTCCTT
TTCTTGACCATTTACTTGGTTACTTTAATGGGCAATGTCCTCATCATCCTGGTCACTATA
GCTGACTCTGCACTACAAAGTCCTATGTACTTCTTCCTCAGAAACTTGTCCTTCCTGGAG
ATAGGTTTCAACTTGGTCATTGTGCCCAAGATGCTGGGGACCCTGATCATTCAAGACACA
ACCATCTCCTTCCTTGGATGTGCCACTCAGATGTATTTCTTCTTCTTTTTTGGGGCTGCT
GAGTGCTGCCTCCTGGCCACCATGGCATATGACCGCTACGTGGCCATCTGTGACCCCTTG
CACTACCCAGTCATCATGGGCCACATATCCTGTGCCCAGCTGGCAGCTGCCTCTTGGTTC
TCAGGGTTTTCAGTGGCCACTGTGCAAACCACATGGATTTTCAGTTTCCCTTTTTGTGGC
CCCAACAGGGTGAACCACTTCTTCTGTGACAGCCCTCCTGTTATTGCACTGGTCTGTGCT
GACACCTCTGTGTTTGAACTGGAGGCTCTGACAGCCACTGTCCTATTCATTCTCTTTCCT
TTCTTGCTGATCCTGGGATCCTATGTCCGCATCCTCTCCACTATCTTCAGGATGCCGTCA
GCTGAGGGGAAACATCAGGCATTCTCCACCTGTTCCGCCCACCTCTTGGTTGTCTCTCTC
TTCTATAGCACTGCCATCCTCACGTATTTCCGACCCCAATCCAGTGCCTCTTCTGAGAGC
AAGAAGCTGCTGTCACTCTCTTCCACAGTGGTGACTCCCATGTTGAACCCCATCATCTAC
AGCTCAAGGAATAAAGAAGTGAAGGCTGCACTGAAGCGGCTTATCCACAGGACCCTGGGC
TCTCAGAAACTA
Conceptual translation MPSEVLGRRMMWENWTIVSEFVLVSFSALSTELQALLFLLFLTIYLVTLMGNVLIILVTI
ADSALQSPMYFFLRNLSFLEIGFNLVIVPKMLGTLIIQDTTISFLGCATQMYFFFFFGAA
ECCLLATMAYDRYVAICDPLHYPVIMGHISCAQLAAASWFSGFSVATVQTTWIFSFPFCG
PNRVNHFFCDSPPVIALVCADTSVFELEALTATVLFILFPFLLILGSYVRILSTIFRMPS
AEGKHQAFSTCSAHLLVVSLFYSTAILTYFRPQSSASSESKKLLSLSSTVVTPMLNPIIY
SSRNKEVKAALKRLIHRTLGSQKL

Protein domains and features

Variations - SNPs

Chr Start End Type Variation AA Change SNP IDs
11 100 -100 NS T/C W/R 1000GP (YRI, YRI, YRI, YRI)
11 100 -100 SYN A/C R/R 1000GP (YRI)
11 6,877,251 6,877,251 NS A/C T/P 1000GP (CHBJPT)
11 6,877,264 6,877,264 NS T/C L/P 1000GP (CEU)
11 6,877,432 6,877,432 NS G/A R/Q 1000GP (CEU, CHBJPT)
11 6,877,527 6,877,527 SYN A/C R/R 1000GP (CEU, CHBJPT)
11 6,898,495 6,898,495 NS C/T P/L rs2595453 (DbSNP)
11 6,898,540 6,898,540 NS A/G H/R rs7938371 (DbSNP)
11 6,898,614 6,898,614 NS C/T L/F rs16919049 (DbSNP)
11 6,898,663 6,898,663 NS A/G Q/R rs10839635 (DbSNP)
11 6,898,758 6,898,758 SYN A/C R/R rs7102808 (DbSNP)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

W163R L206P R221H Q237K L246F R262Q S279Y R304Q % Freq CORP
1 W L R Q L R S R 57.45 0.022
2 W L R Q L Q S R 27.73 0.022
3 W L H Q L R S R 7.76 0.022
4 W L H Q F R S R 3.15 0.022
5 W P R Q L R S R 2.46 0.022
6 R L R Q L R S R 0.46 0.022
7 W L R K L R Y R 0.46 0.022
8 W L R Q L Q S Q 0.31 0.022
9 W P H Q L R S R 0.15 0.022
10 W P R Q L Q S R 0.08 0.022

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession Type Chr Start End Strand
OR10A4.aApr07-unspliced main_exon CDS_partial chr11 6,876,648 6,877,592 +
3UTR chr11 6,877,592 6,877,595 +