OR10G3 Olfactory Receptor
| Gene Symbol | OR10G31 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | 0.09 (functional) |
| Aliases | AE000658-D, OR14-40, HsOR14.2.2, ORL3695 |
| External Ids | HGNC: 8171 GeneBank: AB065893, AF399566, BK004525, NM_001005465 ORDB: ORL3695 |
| Build #39 labels | OR10G3 |
| Chromosomal location | 14:21,569,806-21,570,744 (-) |
| Cluster | 14@22b |
| Synteny | CLIC#35 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10G1P | 75.76% | 297 |
| OR10G2 | 75% | 296 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10G6 | 59% | 303 |
| Mouse | Or10g3 | 87% | 313 |
| Rat | Or10g3 | 86% | 313 |
| Rat | Or10g3c | 83% | 313 |
| Cow | OR10G1 | 76% | 307 |
| Orang | OR10G3D | 97% | 313 |
| Horse | OR10G1G | 75% | 307 |
| Chimp | OR10G1 | 76% | 298 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB528817 |
| GNF Atlas2 | gnf1h02180_at |
Sequence information
| Nucleotide sequence |
ATGGAAAGAATCAACAGCACACTGTTGACTGCGTTTATCCTGACAGGAATTCCGTATCCA CTCAGGCTAAGGACACTCTTTTTTGTGTTCTTTTTTCTAATCTACATCCTGACTCAGCTG GGAAACCTGCTTATTTTAATCACTGTCTGGGCAGACCCAAGGCTCCATGCCCGCCCCATG TACATCTTTCTTGGTGTTCTCTCAGTCATTGATATGAGCATCTCCTCCATCATTGTCCCT CGCCTCATGATGAACTTCACTTTAGGTGTCAAACCCATCCCATTTGGTGGCTGTGTTGCT CAACTCTATTTCTATCACTTCCTGGGCAGCACCCAGTGCTTCCTCTACACCCTAATGGCC TATGACAGGTACCTGGCAATATGTCAGCCCCTGCGCTACCCTGTGCTCATGACTGCTAAG CTGAGCGCCTTGCTTGTGGCTGGAGCCTGGATGGCAGGATCCATCCATGGGGCTCTCCAG GCCATCCTAACCTTCCGCCTGCCCTACTGTGGGCCCAATCAGGTGGATTACTTCTTCTGT GACATCCCTGCAGTGTTGAGACTGGCCTGTGCTGACACAACAGTCAACGAGCTGGTGACG TTTGTAGACATTGGGGTGGTGGTTGCCAGTTGCTTCTCCCTGATCCTCCTCTCCTACATA CAGATCATTCAGGCCATCCTGAGAATCCACACAGCTGATGGGCGGCGCCGGGCTTTTTCA ACTTGTGGAGCCCATGTAACCGTGGTCACCGTGTACTATGTGCCCTGTGCCTTCATCTAC CTGAGGCCTGAAACCAACAGCCCCCTGGATGGGGCAGCTGCCCTAGTCCCCACGGCCATC ACTCCTTTCCTCAACCCCCTTATCTACACTCTGCGGAACCAAGAGGTGAAGCTGGCCCTG AAAAGAATGCTCAGAAGCCCAAGAACTCCGAGTGAGGTT |
| Conceptual translation |
MERINSTLLTAFILTGIPYPLRLRTLFFVFFFLIYILTQLGNLLILITVWADPRLHARPM YIFLGVLSVIDMSISSIIVPRLMMNFTLGVKPIPFGGCVAQLYFYHFLGSTQCFLYTLMA YDRYLAICQPLRYPVLMTAKLSALLVAGAWMAGSIHGALQAILTFRLPYCGPNQVDYFFC DIPAVLRLACADTTVNELVTFVDIGVVVASCFSLILLSYIQIIQAILRIHTADGRRRAFS TCGAHVTVVTVYYVPCAFIYLRPETNSPLDGAAALVPTAITPFLNPLIYTLRNQEVKLAL KRMLRSPRTPSEV Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 22,038,650 | 22,038,650 | NS | A/T | S/T | rs12887316 (DbSNP) |
| 14 | 22,038,731 | 22,038,731 | NS | C/G | V/L | rs12886819 (DbSNP) |
| 14 | 22,038,659 | 22,038,659 | NS | C/T | G/S | rs17792778 (DbSNP) |
| 14 | 22,038,125 | 22,038,125 | NS | C/T | V/M | rs34162196 (DbSNP) |
| 14 | 22,038,562 | 22,038,562 | NS | C/T | C/Y | rs45612332 (DbSNP) |
| 14 | 22,038,379 | 22,038,379 | NS | T/C | H/R | rs61743457 (DbSNP) |
| 14 | 22,038,268 | 22,038,268 | NS | T/G | D/A | rs61738890 (DbSNP) |
| 14 | 22,038,162 | 22,038,162 | SYN | A/C | A/A | rs17197261 (DbSNP) |
| 14 | 22,038,450 | 22,038,450 | SYN | A/G | S/S | rs11626669 (DbSNP) |
| 14 | 22,038,276 | 22,038,276 | SYN | C/T | T/T | rs28436899 (DbSNP) |
| 14 | 22,038,377 | 22,038,377 | SYN | G/A | L/L | rs61743458 (DbSNP) |
| 14 | 22,038,798 | 22,038,798 | SYN | G/A | L/L | rs61744486 (DbSNP) |
| 14 | 22,038,525 | 22,038,525 | SYN | G/T | T/T | rs11626693 (DbSNP) |
| 14 | 22,038,210 | 22,038,210 | SYN | G/T | I/I | rs17792766 (DbSNP) |
| 14 | 21,570,031 | 21,570,031 | SYN | A/C | A/A | 1000GP (CEU) |
| 14 | 21,570,431 | 21,570,431 | NS | T/C | Y/C | 1000GP (CEU) |
| 14 | 21,570,528 | 21,570,528 | NS | T/C | S/G | 1000GP (CEU, CHBJPT) |
| 14 | 21,570,079 | 21,570,079 | SYN | G/T | I/I | 1000GP (CEU) |
| 14 | 21,570,600 | 21,570,600 | NS | C/G | V/L | 1000GP (CEU) |
| 14 | 21,569,994 | 21,569,994 | NS | C/T | V/M | 1000GP (CEU) |
| 14 | 21,570,319 | 21,570,319 | SYN | G/A | S/S | 1000GP (CEU, CHBJPT) |
| 14 | 21,570,394 | 21,570,394 | SYN | G/T | T/T | 1000GP (CEU, CHBJPT) |
| 14 | 21,570,513 | 21,570,513 | NS | T/C | I/V | 1000GP (CEU) |
| 14 | 21,569,870 | 21,569,870 | NS | C/T | R/Q | 1000GP (CHBJPT) |
| 14 | 21,569,960 | 21,569,960 | NS | C/T | R/K | 1000GP (CHBJPT) |
| 14 | 100 | -100 | SYN | G/T | I/I | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 14 | 100 | -100 | NS | T/C | S/G | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 21,931,624 | 22,169,502 | CopyNumber | Variation_5318 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R292Q | R262K | V251M | R235Q | V202I | Y105C | I78V | S73G | V49L | I45M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | R | V | R | V | Y | I | G | V | I | 62.44 | 0.109 |
| 2 | R | R | V | R | V | Y | I | S | V | I | 26.19 | 0.109 |
| 3 | R | R | M | R | V | Y | I | G | V | I | 4.61 | 0.109 |
| 4 | R | R | V | R | V | C | I | G | V | I | 1.92 | 0.109 |
| 5 | Q | R | V | R | V | Y | I | S | V | I | 1.46 | 0.109 |
| 6 | R | R | V | R | V | Y | I | S | L | I | 1.23 | 0.109 |
| 7 | R | K | V | R | V | Y | I | G | V | I | 0.69 | 0.109 |
| 8 | R | R | V | Q | V | Y | I | S | V | I | 0.46 | 0.109 |
| 9 | R | R | V | R | I | Y | I | G | V | I | 0.38 | 0.109 |
| 10 | R | R | V | R | V | Y | V | G | V | I | 0.31 | 0.109 |
| 11 | R | R | V | Q | V | Y | I | G | V | I | 0.08 | 0.109 |
| 12 | R | R | V | R | V | Y | I | G | V | M | 0.08 | 0.109 |
| 13 | R | R | M | R | V | Y | I | S | V | I | 0.08 | 0.109 |
| 14 | R | R | V | R | V | Y | I | G | L | I | 0.08 | 0.109 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10G3.aApr07-unspliced | main_exon | 3UTR | chr14 | 21,569,803 | 21,569,806 | - |
| CDS | chr14 | 21,569,806 | 21,570,744 | - | ||