OR10Z1 Olfactory Receptor
| Gene Symbol | OR10Z11 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | Z |
| Pseudogene | No |
| CORP pseudogene probability score | 0.15 (functional) |
| Aliases | OR1-15, HsOR1.4.10, ORL3004 |
| External Ids | HGNC: 14996 GeneBank: AB065635, BK004195, NM_001004478 ORDB: ORL3004 |
| Build #39 labels | OR10Z1 |
| Chromosomal location | 1:158,606,439-158,607,377 (+) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10R2 | 54.22% | 308 |
| OR10R3P | 54.87% | 308 |
| OR10T1P | 52.58% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10J7 | 55% | 312 |
| Mouse | Or10z1 | 88% | 313 |
| Rat | Or10z1 | 86% | 313 |
| Cow | OR10R2 | 55% | 308 |
| Orang | OR10Z1BP | 81% | 341 |
| Horse | OR10R3 | 54% | 312 |
| Chimp | OR10R2 | 55% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529288 |
| GNF Atlas2 | gnf1h01972_at |
Sequence information
| Nucleotide sequence |
ATGGGGCAGACCAACGTAACCTCCTGGAGGGATTTTGTCTTCCTGGGCTTCTCCAGTTCT GGGGAGTTGCAGCTCCTTCTCTTTGCCTTGTTCCTCTCTCTGTATCTAGTCACTCTGACC AGCAATGTCTTCATTATCATAGCCATCAGGCTGGATAGCCATCTGCACACCCCCATGTAC CTCTTCCTTTCCTTCCTATCCTTCTCTGAGACCTGCTACACTTTGGGCATCATCCCTAGA ATGCTCTCTGGCCTGGCTGGGGGGGACCAGGCTATCTCCTATGTGGGCTGTGCTGCCCAG ATGTTCTTTTCTGCCTCATGGGCCTGTACTAACTGCTTCCTTCTGGCTGCCATGGGCTTT GACAGATATGTGGCCATCTGTGCTCCACTCCACTATGCCAGCCACATGAATCCTACCCTC TGTGCCCAGCTGGTCATTACTTCCTTCCTGACTGGATACCTCTTTGGACTGGGAATGACA CTAGTTATTTTCCACCTCTCATTCTGCAGCTCCCATGAAATCCAGCACTTTTTTTGTGAC ACGCCACCTGTGCTGAGCCTAGCCTGTGGAGATACAGGCCCGAGTGAGCTGAGGATCTTT ATCCTCAGTCTTTTGGTCCTCTTGGTCTCCTTCTTCTTCATCACCATCTCCTACGCCTAC ATCTTGGCAGCAATACTGAGGATCCCCTCTGCTGAGGGGCAGAAGAAGGCCTTCTCCACT TGTGCCTCGCACCTTACAGTGGTCATTATTCATTATGGCTGTGCTTCCTTCGTGTACCTG AGGCCCAAAGCCAGCTACTCTCTTGAGAGAGATCAGCTTATTGCCATGACCTATACTGTA GTGACCCCCCTCCTTAATCCCATTGTTTATAGTCTAAGGAATAGGGCTATACAGACAGCT CTGAGGAATGCTTTCAGAGGGAGATTGCTGGGTAAAGGA |
| Conceptual translation |
MGQTNVTSWRDFVFLGFSSSGELQLLLFALFLSLYLVTLTSNVFIIIAIRLDSHLHTPMY LFLSFLSFSETCYTLGIIPRMLSGLAGGDQAISYVGCAAQMFFSASWACTNCFLLAAMGF DRYVAICAPLHYASHMNPTLCAQLVITSFLTGYLFGLGMTLVIFHLSFCSSHEIQHFFCD TPPVLSLACGDTGPSELRIFILSLLVLLVSFFFITISYAYILAAILRIPSAEGQKKAFST CASHLTVVIIHYGCASFVYLRPKASYSLERDQLIAMTYTVVTPLLNPIVYSLRNRAIQTA LRNAFRGRLLGKG Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | C/A | H/N | 1000GP (YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | / | G/G | 1000GP (YRI) |
| 1 | 158,576,712 | 158,576,712 | NS | G/T | V/F | rs28565358 (DbSNP) |
| 1 | 158,576,973 | 158,576,973 | NS | A/G | I/V | rs41273513 (DbSNP) |
| 1 | 158,577,109 | 158,577,109 | NS | A/C | N/T | rs857685 (DbSNP) |
| 1 | 158,577,167 | 158,577,167 | SYN | A/T | G/G | rs2427808 (DbSNP) |
| 1 | 158,607,183 | 158,607,183 | NS | A/G | I/V | 1000GP (CEU) |
| 1 | 158,607,319 | 158,607,319 | NS | A/C | N/T | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| H56N | L82F | G87V | Y153* | V162F | I249V | N294T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | H | L | G | Y | V | I | N | 70.05 | 0.253 |
| 2 | H | L | G | Y | V | I | T | 23.81 | 0.253 |
| 3 | H | F | G | Y | V | I | N | 2.84 | 0.203 |
| 4 | H | L | G | * | V | I | N | 1.54 | 1.200 |
| 5 | H | L | G | Y | V | V | N | 0.77 | 0.253 |
| 6 | H | L | G | Y | F | I | N | 0.46 | 0.253 |
| 7 | N | L | G | Y | V | I | N | 0.38 | 0.253 |
| 8 | H | L | G | Y | V | V | T | 0.08 | 0.253 |
| 9 | H | L | V | Y | V | I | N | 0.08 | 0.253 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10Z1.aApr07-unspliced | main_exon | CDS | chr1 | 158,606,439 | 158,607,377 | + |
| 3UTR | chr1 | 158,607,377 | 158,607,380 | + | ||