OR12D3 Olfactory Receptor
| Gene Symbol | OR12D31 (View this gene in GeneCards) |
| Family | 12 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR6-27, hs6M1-27, bA150A6.1, HsOR6.3.18, ORL1030 |
| External Ids | HGNC: 13963 GeneBank: BC069082, BC069154, BK004439, HSA459858, NM_030959 ORDB: ORL1030 |
| Build #39 labels | OR12D3 |
| Chromosomal location | 6:29,374,340-29,375,287 (-) |
| Cluster | 6@29 |
| Synteny | CLIC#12 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR12D1P | 67.96% | 309 |
| OR12D2 | 66.99% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1I1 | 47% | 311 |
| Mouse | Or12d17 | 80% | 312 |
| Rat | Or12d17 | 79% | 317 |
| Cow | OR12D20 | 75% | 308 |
| Orang | OR12D3P | 94% | 315 |
| Horse | OR12D20 | 76% | 308 |
| Chimp | OR12D3P | 98% | 259 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB464427 |
| GNF Atlas2 | 221431_s_at |
Sequence information
| Nucleotide sequence |
ATGGAGAATGTCACTACAATGAATGAGTTTCTTCTACTTGGCCTGACTGGTGTTCAGGAG CTGCAGCCTTTCTTCTTTGGGATTTTCTTAATCATTTACCTGATAAACTTGATTGGAAAT GGATCTATATTGGTGATGGTTGTTTTGGAACCACAACTCCACTCCCCTATGTATTTTTTT CTGGGAAACCTTTCTTGTCTGGATATTTCTTATTCTTCAGTGACACTGCCCAAGCTGCTC GTAAACCTCGTGTGCAGTCGCAGGGCTATATCTTTTCTAGGCTGTATCACCCAGCTACAC TTCTTCCACTTTTTGGGAAGCACAGAGGCCATTTTACTGGCTATCATGGCCTTTGACCGT TTTGTTGCCATCTGCAATCCTCTTCGCTACACTGTCATCATGAACCCCCAGGTGTGTATT CTGTTGGCAGCTGCGGCCTGGCTCATCAGCTTCTTTTACGCTCTGATGCATTCTGTCATG ACTGCACACCTGAGTTTTTGTGGCTCTCAGAAACTCAATCACTTCTTCTACGATGTCAAG CCGCTCTTAGAATTGGCCTGTAGTGACACATTACTCAATCAATGGCTTCTTTCCATTGTC ACAGGCAGCATATCCATGGGAGCTTTCTTTCTGACTCTTCTCTCCTGCTTCTATGTAATT GGCTTCCTTCTGTTTAAGAACAGGTCCTGCAGAATACTCCACAAGGCTCTGTCCACTTGT GCCTCCCATTTTATGGTGGTATGTCTTTTCTATGGACCTGTGGGCTTCACATATATTCGT CCTGCTTCAGCCACCTCCATGATTCAGGACCGGATAATGGCCATCATGTATAGCGCCGTC ACCCCTGTACTGAATCCACTAATCTACACCCTTAGGAACAAAGAAGTGATGATGGCTCTG AAGAAAATCTTTGGTAGGAAGTTGTTTAAAGACTGGCAGCAACACCAC |
| Conceptual translation |
MENVTTMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFF LGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDR FVAICNPLRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVK PLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTC ASHFMVVCLFYGPVGFTYIRPASATSMIQDRIMAIMYSAVTPVLNPLIYTLRNKEVMMAL KKIFGRKLFKDWQQHH Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 6 | 29,342,236 | 29,342,236 | NS | A/G | Y/H | rs9380122 (DbSNP) |
| 6 | 29,342,775 | 29,342,775 | NS | G/A | T/I | rs3749971 (DbSNP) |
| 6 | 29,342,630 | 29,342,630 | SYN | C/T | A/A | rs34525583 (DbSNP) |
| 6 | 29,342,825 | 29,342,825 | SYN | G/A | L/L | rs3749970 (DbSNP) |
| 6 | 29,374,853 | 29,374,853 | SYN | C/T | A/A | 1000GP (CEU, CHBJPT) |
| 6 | 29,374,459 | 29,374,459 | NS | A/G | Y/H | 1000GP (CEU, CHBJPT) |
| 6 | 29,374,998 | 29,374,998 | NS | G/A | T/I | 1000GP (CEU, CHBJPT) |
| 6 | 29,375,048 | 29,375,048 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 6 | 100 | -100 | NS | A/G | Y/H | 1000GP (YRI) |
| 6 | 100 | -100 | SYN | C/T | A/A | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Y277H | T97I | % Freq | CORP | |
|---|---|---|---|---|
| 1 | Y | T | 86.25 | 1.000 |
| 2 | H | T | 8.60 | 1.000 |
| 3 | Y | I | 5.15 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR12D3.aApr07-unspliced | main_exon | 3UTR | chr6 | 29,373,423 | 29,374,340 | - |
| CDS | chr6 | 29,374,340 | 29,375,287 | - | ||
| 5UTR | chr6 | 29,375,287 | 29,375,291 | - | ||