OR1G1 Olfactory Receptor
| Gene Symbol | OR1G11 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | 0.36 (functional) |
| Aliases | OR17-209, OR17-130, OR17-8, HsOR17.1.4, ORL3747 |
| External Ids | HGNC: 8204 GeneBank: AF087928, BC069379, BK004243, HSU04689, NM_003555, U86240 ORDB: ORL3747 |
| Build #39 labels | OR1G1 |
| Chromosomal location | 17:3,126,613-3,127,551 (-) |
| Cluster | 17@3b |
| Synteny | CLIC#39 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1F1 | 56.72% | 305 |
| OR7A10 | 58.94% | 302 |
| OR7A5 | 59.28% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7A51 | 60% | 307 |
| Mouse | Or7a36 | 56% | 308 |
| Rat | Or1ad6 | 55% | 312 |
| Cow | OR1G4 | 79% | 312 |
| Orang | OR7A10C | 60% | 309 |
| Horse | OR1G1P | 84% | 311 |
| Chimp | OR7A2P | 58% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DN693331 |
| mRNA | AB529303 |
| GNF Atlas2 | 221375_at |
Sequence information
| Nucleotide sequence |
ATGGAGGGGAAAAATCTGACCAGCATCTCAGAATGTTTCCTCCTGGGGTTCTCTGAGCAG CTGGAGGAGCAGAAGCCCCTCTTTGGGTCCTTCCTGTTCATGTACTTGGTCACGGTGGCA GGCAACCTCCTCATCATTCTAGTCATCATTACTGACACTCAACTCCATACCCCCATGTAC TTCTTTCTAGCCAACCTCTCCCTTGCAGATGCCTGCTTTGTGTCCACCACAGTCCCTAAG ATGCTGGCAAACATACAGATCCAGAGTCAGGCCATCTCCTACTCAGGGTGTCTACTACAG TTGTATTTTTTCATGTTATTTGTGATGCTGGAGGCATTCCTCTTGGCGGTCATGGCCTAT GACTGCTACGTGGCCATATGCCACCCACTTCATTACATTCTGATCATGAGCCCTGGGCTC TGCATCTTCCTCGTGTCTGCATCCTGGATCATGAATGCCCTCCACTCCCTTCTACACACA CTTCTGATGAACAGCCTGTCCTTCTGCGCAAACCATGAGATCCCACACTTCTTCTGTGAC ATCAATCCCCTCCTGAGTCTGTCCTGCACAGACCCCTTCACCAATGAGCTGGTGATCTTC ATCACTGGGGGTCTCACAGGACTCATTTGTGTGCTTTGCCTGATTATCTCTTACACGAAC GTTTTCTCGACCATCCTGAAGATCCCATCAGCTCAGGGGAAGCGGAAAGCCTTTTCCACC TGCAGCTCTCATCTCTCCGTGGTCTCTCTCTTCTTTGGGACTTCTTTTTGTGTTGATTTC AGTTCTCCCTCAACCCACTCGGCCCAGAAGGACACAGTTGCATCAGTGATGTACACAGTG GTAACTCCAATGTTGAATCCCTTTATCTACAGTTTGAGGAACCAAGAAATAAAGTCTTCC CTGAGAAAGTTAATCTGGGTTCGGAAAATTCATTCCCCT |
| Conceptual translation |
MEGKNLTSISECFLLGFSEQLEEQKPLFGSFLFMYLVTVAGNLLIILVIITDTQLHTPMY FFLANLSLADACFVSTTVPKMLANIQIQSQAISYSGCLLQLYFFMLFVMLEAFLLAVMAY DCYVAICHPLHYILIMSPGLCIFLVSASWIMNALHSLLHTLLMNSLSFCANHEIPHFFCD INPLLSLSCTDPFTNELVIFITGGLTGLICVLCLIISYTNVFSTILKIPSAQGKRKAFST CSSHLSVVSLFFGTSFCVDFSSPSTHSAQKDTVASVMYTVVTPMLNPFIYSLRNQEIKSS LRKLIWVRKIHSP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 17 | 100 | -100 | NS | G/A | S/F | 1000GP (YRI, YRI) |
| 17 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI, YRI, YRI) |
| 17 | 3,030,130 | 3,030,130 | NS | G/A | S/F | rs61736117 (DbSNP) |
| 17 | 3,030,291 | 3,030,291 | SYN | T/C | L/L | rs61736116 (DbSNP) |
| 17 | 3,030,477 | 3,030,477 | SYN | G/A | Y/Y | rs61736115 (DbSNP) |
| 17 | 3,030,482 | 3,030,481 | Ins(1) | -/C | rs34207115 (DbSNP) | |
| 17 | 3,030,582 | 3,030,582 | NS | C/G | Q/H | rs9892491 (DbSNP) |
| 17 | 3,030,676 | 3,030,676 | NS | G/A | T/I | rs61736114 (DbSNP) |
| 17 | 3,127,382 | 3,127,382 | NS | G/A | T/I | 1000GP (CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 17 | 3,018,447 | 3,159,865 | CopyNumber | Variation_2217 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S239F | V145M | Q88H | T57I | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | S | V | Q | T | 84.38 | 0.602 |
| 2 | S | V | H | T | 13.04 | 0.602 |
| 3 | F | V | Q | T | 1.49 | 0.703 |
| 4 | S | V | Q | I | 0.82 | 0.602 |
| 5 | S | M | Q | T | 0.27 | 0.602 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1G1.aApr07-unspliced | main_exon | 3UTR | chr17 | 3,126,584 | 3,126,613 | - |
| CDS | chr17 | 3,126,613 | 3,127,551 | - | ||
| 5UTR | chr17 | 3,127,551 | 3,127,582 | - | ||