OR1I1 Olfactory Receptor
Gene Symbol | OR1I11 (View this gene in GeneCards) |
Family | 1 |
Subfamily | I |
Pseudogene | No |
CORP pseudogene probability score | 0 (functional) |
Aliases | OR19-20, F20569, HsOR19.3.12, ORL314 |
External Ids | HGNC: 8207 GeneBank: AF399548, NM_001004713 ORDB: ORL314 |
Build #39 labels | OR1I1 |
Chromosomal location | 19:15,087,066-15,088,010 (+) |
Cluster | 19@15b |
Synteny | CLIC#45 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR1F1 | 56.49% | 308 |
OR1N1 | 56.81% | 301 |
OR1N2 | 56.19% | 299 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR1F15 | 57% | 312 |
Mouse | Or1i2 | 77% | 307 |
Rat | Or1i2 | 76% | 307 |
Cow | OR1I3 | 76% | 314 |
Orang | OR1F1 | 58% | 308 |
Horse | OR1I5 | 80% | 311 |
Chimp | OR1G1 | 56% | 313 |
Expression evidences
Source | Accession |
---|---|
mRNA | AB529304 |
Sequence information
Nucleotide sequence |
ATGGAACCAGAAAAGCAAACCGAAATCTCAGAATTCTTCCTCCAGGGACTCTCAGAAAAG CCAGAGCATCAGACCCTCCTCTTCACAATGTTCCTCTCCACATACCTGGTCACCATCATT GGAAATGCCCTCATTATCCTGGCCATCATCACGGACTCTCACCTCCACACACCCATGTAC TTCTTTCTCTTCAACCTCTCACTCGTTGACACCCTATTATCCTCCACCACCGTCCCCAAG ATGCTAGCGAACATCCAGGCTCAGAGCAGAGCCATCCCCTTTGTGGGCTGCCTCACCCAG ATGTATGCCTTCCACCTGTTCGGGACCATGGACAGCTTTCTCCTGGCAGTAATGGCCATC GACCGCTTCGTGGCCATTGTCCACCCACAGCGTTACTTGGTTCTCATGTGCTCCCCTGTC TGTGGGCTGCTGCTGGGAGCATCATGGATGATCACCAACCTCCAGTCTCTCATACACACC TGCCTCATGGCTCAACTGACCTTCTGCGCCGGCTCTGAAATCTCCCACTTCTTCTGTGAC CTCATGCCCCTGCTGAAGCTCTCCGGCTCAGACACGCACACCAACGAGCTGGTGATCTTT GCTTTTGGCATTGTCGTGGGCACCAGCCCATTCTCCTGCATCCTTCTCTCGTACATCCGC ATTTTCTGGACAGTCTTTAAGATCCCTTCTACTCGGGGCAAGTGGAAAGCCTTCTCCACC TGTGGCTTACACCTCACTGTGGTGTCACTGTCCTATGGGACCATCTTTGCTGTGTACTTA CAGCCCACATCCCCCAGCTCCTCCCAGAAGGACAAGGCAGCCGCCCTAATGTGTGGGGTG TTCATCCCCATGCTCAACCCCTTTATCTACAGCATACGGAACAAGGATATGAAGGCAGCC CTGGGGAAGCTCATCGGCAAAGTGGCCGTCCCCTGTCCTAGGCCA |
Conceptual translation |
MEPEKQTEISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMY FFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAI DRFVAIVHPQRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCD LMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTVFKIPSTRGKWKAFST CGLHLTVVSLSYGTIFAVYLQPTSPSSSQKDKAAALMCGVFIPMLNPFIYSIRNKDMKAA LGKLIGKVAVPCPRP Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
19 | 100 | -100 | NS | G/A | E/K | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
19 | 100 | -100 | SYN | A/G | P/P | 1000GP (YRI, YRI, YRI) |
19 | 15,087,213 | 15,087,213 | NS | A/T | I/F | 1000GP (CEU, CHBJPT) |
19 | 15,087,389 | 15,087,389 | SYN | G/A | G/G | 1000GP (CHBJPT) |
19 | 15,087,452 | 15,087,452 | SYN | A/G | P/P | 1000GP (CEU, CHBJPT) |
19 | 15,087,481 | 15,087,481 | NS | C/G | P/R | 1000GP (CEU, CHBJPT) |
19 | 15,087,552 | 15,087,552 | NS | A/C | M/L | 1000GP (CEU, CHBJPT) |
19 | 15,087,630 | 15,087,630 | NS | G/T | G/C | 1000GP (CEU, CHBJPT) |
19 | 15,087,696 | 15,087,696 | NS | T/C | F/L | 1000GP (CEU, CHBJPT) |
19 | 15,087,795 | 15,087,795 | NS | C/T | H/Y | 1000GP (CEU, CHBJPT) |
19 | 15,087,813 | 15,087,813 | SYN | C/T | L/L | 1000GP (CEU, CHBJPT) |
19 | 15,087,820 | 15,087,820 | NS | A/C | Y/S | 1000GP (CEU, CHBJPT) |
19 | 15,087,909 | 15,087,909 | NS | A/T | I/F | 1000GP (CEU, CHBJPT) |
19 | 15,087,940 | 15,087,940 | NS | T/C | I/T | 1000GP (CEU, CHBJPT) |
19 | 15,087,953 | 15,087,953 | SYN | T/C | D/D | 1000GP (CEU, CHBJPT) |
19 | 15,197,898 | 15,197,898 | NS | A/G | K/E | rs73522019 (DbSNP) |
19 | 15,198,024 | 15,198,024 | NS | A/T | I/F | rs59166286 (DbSNP) |
19 | 15,198,263 | 15,198,263 | SYN | A/G | P/P | rs8105277 (DbSNP) |
19 | 15,198,292 | 15,198,292 | NS | C/G | P/R | rs8104843 (DbSNP) |
19 | 15,198,322 | 15,198,321 | Ins(1) | -/G | rs35240562 (DbSNP) | |
19 | 15,198,441 | 15,198,441 | NS | G/T | G/C | rs73008811 (DbSNP) |
19 | 15,198,507 | 15,198,507 | NS | C/T | L/F | rs8108721 (DbSNP) |
19 | 15,198,551 | 15,198,551 | SYN | C/T | V/V | rs16980310 (DbSNP) |
19 | 15,198,606 | 15,198,606 | NS | C/T | H/Y | rs73008812 (DbSNP) |
19 | 15,198,631 | 15,198,631 | NS | A/C | Y/S | rs8105737 (DbSNP) |
19 | 15,198,751 | 15,198,751 | NS | C/T | T/I | rs16980312 (DbSNP) |
19 | 15,198,764 | 15,198,764 | SYN | C/T | D/D | rs12975625 (DbSNP) |
19 | 15,198,780 | 15,198,780 | NS | A/G | R/G | rs35396476 (DbSNP) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
19 | 15,096,950 | 15,259,179 | CopyNumber | Variation_4068 (DGV) |
19 | 15,197,777 | 15,200,821 | CopyNumber | #131 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
E8K | L14F | A43D | I50F | R122H | P139R | M163L | G189C | F211L | R220H | H244Y | Y252S | S264T | I282F | I292T | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | E | L | A | I | R | R | M | G | L | R | H | S | S | I | I | 48.16 | 0.001 |
2 | E | L | A | I | R | P | M | G | F | R | H | Y | S | I | I | 27.88 | 0.002 |
3 | E | L | A | F | R | R | M | C | L | R | Y | Y | S | I | T | 15.05 | 0.026 |
4 | E | L | A | I | R | P | L | G | F | R | H | Y | S | F | I | 3.46 | 0.002 |
5 | K | L | A | I | H | P | M | G | F | R | H | Y | S | I | I | 2.38 | 0.034 |
6 | E | L | A | I | R | R | M | G | L | H | H | S | S | I | I | 1.15 | 0.001 |
7 | E | L | A | I | R | R | M | G | L | R | H | S | T | I | I | 0.77 | 0.001 |
8 | E | L | A | I | R | P | M | G | L | R | H | Y | S | I | I | 0.31 | 0.002 |
9 | E | L | A | F | R | R | M | C | L | R | Y | Y | S | I | I | 0.15 | 0.026 |
10 | E | L | D | I | R | R | M | G | L | R | H | S | S | I | I | 0.15 | 0.001 |
11 | E | L | A | I | R | R | M | G | F | R | H | S | S | I | I | 0.15 | 0.001 |
12 | E | L | A | I | R | P | M | G | L | R | H | S | S | I | I | 0.08 | 0.001 |
13 | E | L | A | I | R | P | L | G | F | R | H | Y | S | F | T | 0.08 | 0.002 |
14 | E | L | A | I | R | R | M | G | L | R | Y | Y | S | I | I | 0.08 | 0.027 |
15 | E | F | A | I | R | R | M | G | L | R | H | S | S | I | I | 0.08 | 0.001 |
16 | E | L | A | F | R | P | M | C | L | R | Y | Y | S | I | T | 0.08 | 0.026 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR1I1.aApr07-unspliced | main_exon | CDS | chr19 | 15,087,066 | 15,088,010 | + |
3UTR | chr19 | 15,088,010 | 15,088,133 | + |