OR1L1 Olfactory Receptor
| Gene Symbol | OR1L11 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | L |
| Pseudogene | No |
| CORP pseudogene probability score | 0 (functional) |
| Aliases | hRPK-465_F_21, hg23, OR9-27, OR9-C, HsOR9.6.10 |
| External Ids | HGNC: 8213 GeneBank: AB065491, BK004230, NM_001005236 |
| Build #39 labels | OR1L1 |
| Chromosomal location | 9:122,661,716-122,662,645 (+) |
| Cluster | 9@125 |
| Synteny | CLIC#21 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1L3 | 78.06% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1L8 | 71% | 311 |
| Mouse | Or1l8 | 73% | 305 |
| Rat | Or1l8 | 73% | 309 |
| Cow | OR1L19 | 75% | 310 |
| Orang | OR1L1P | 96% | 309 |
| Horse | OR1L12 | 79% | 310 |
| Chimp | OR1L12P | 77% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463952 |
| GNF Atlas2 | gnf1h10922_at |
Sequence information
| Nucleotide sequence |
ATGGGAAGAAATAACCTAACAAGACCCTCTGAATTCATCCTCCTTGGACTCTCCTCTCGA CCTGAGGATCAGAAGCCGCTCTTTGCTGTGTTCCTCCCCATCTACCTTATCACAGTGATA GGAAACCTGCTTATCATCCTGGCCATCCGCTCAGACACTCGTCTCCAGACGCCCATGTAC TTCTTTCTAAGCATCCTGTCTTTTGTTGACATTTGCTATGTGACAGTCATTATCCCTAAG ATGCTGGTGAACTTCTTATCAGAGACAAAGACCATCTCTTACAGTGAGTGTCTGACCCAG ATGTACTTTTTCTTAGCCTTTGGAAACACAGACAGTTACCTGCTAGCAGCCATGGCCATT GACCGCTATGTGGCCATATGTAATCCCTTCCACTACATCACCATTATGAGTCACAGATGC TGTGTCCTGCTTCTGGTTCTCTCCTTCTGCATTCCACATTTTCACTCCCTCCTGCACATT CTTCTGACTAATCAGCTCATCTTCTGTGCCTCAAATGTCATCCATCACTTTTTCTGCGAT GATCAACCAGTGCTAAAATTGTCCTGTTCCTCCCATTTTGTCAAAGAAATCACAGTAATG ACAGAAGGCTTGGCTGTCATAATGACCCCGTTTTCATGCATCATCATCTCTTATTTAAGA ATCCTCATCACTGTTCTGAAGATTCCTTCAGCTGCTGGAAAGCGTAAAGCATTTTCTACC TGTGGCTCTCATCTCACAGTGGTGACCCTGTTTTATGGAAGCATTAGCTATCTCTATTTT CAGCCCCTGTCCAACTATACTGTCAAGGATCAAATAGCAACAATTATCTACACCGTACTG ACTCCTATGCTAAATCCATTTATCTATAGTCTGAGGAACAAAGACATGAAGCAGGGTTTG GCAAAGTTGATGCACAGGATGAAATGTCAG |
| Conceptual translation |
MGRNNLTRPSEFILLGLSSRPEDQKPLFAVFLPIYLITVIGNLLIILAIRSDTRLQTPMY FFLSILSFVDICYVTVIIPKMLVNFLSETKTISYSECLTQMYFFLAFGNTDSYLLAAMAI DRYVAICNPFHYITIMSHRCCVLLLVLSFCIPHFHSLLHILLTNQLIFCASNVIHHFFCD DQPVLKLSCSSHFVKEITVMTEGLAVIMTPFSCIIISYLRILITVLKIPSAAGKRKAFST CGSHLTVVTLFYGSISYLYFQPLSNYTVKDQIATIIYTVLTPMLNPFIYSLRNKDMKQGL AKLMHRMKCQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 125,424,289 | 125,424,289 | NS | A/G | T/A | rs16912055 (DbSNP) |
| 9 | 125,424,277 | 125,424,277 | NS | A/G | S/G | rs70157 (DbSNP) |
| 9 | 125,424,189 | 125,424,189 | NS | C/G | I/M | rs73571128 (DbSNP) |
| 9 | 125,424,766 | 125,424,766 | NS | C/G | L/V | rs237620 (DbSNP) |
| 9 | 125,424,889 | 125,424,889 | NS | C/G | R/G | rs16912062 (DbSNP) |
| 9 | 125,424,507 | 125,424,507 | SYN | A/C | S/S | rs70156 (DbSNP) |
| 9 | 122,662,228 | 122,662,228 | SYN | A/C | S/S | 1000GP (CEU, CHBJPT) |
| 9 | 122,661,910 | 122,661,910 | NS | C/G | I/M | 1000GP (CHBJPT) |
| 9 | 100 | -100 | NS | C/T | T/M | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 9 | 100 | -100 | SYN | G/C | T/T | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 9 | 125,423,895 | 125,426,924 | CopyNumber | #152 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R54H | T57M | I65M | S93F | S95G | T99A | L258V | M283T | G299R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | T | I | S | S | T | L | M | G | 79.34 | 0.013 |
| 2 | R | T | M | S | S | T | L | M | G | 7.30 | 0.013 |
| 3 | R | T | I | S | G | T | V | M | G | 7.14 | 0.013 |
| 4 | R | T | I | S | G | T | L | M | G | 2.69 | 0.013 |
| 5 | R | T | I | S | G | A | L | M | G | 1.15 | 0.013 |
| 6 | R | T | I | S | S | T | L | M | R | 0.84 | 0.013 |
| 7 | R | M | I | S | G | T | L | M | G | 0.84 | 0.013 |
| 8 | R | M | I | F | G | T | L | T | G | 0.23 | 0.013 |
| 9 | H | T | I | S | S | T | L | M | G | 0.23 | 0.013 |
| 10 | R | M | I | S | S | T | L | M | G | 0.08 | 0.013 |
| 11 | R | T | I | S | S | T | V | M | G | 0.08 | 0.013 |
| 12 | R | T | M | S | G | A | L | M | G | 0.08 | 0.013 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1L1.aApr07-unspliced | main_exon | 5UTR | chr9 | 122,661,566 | 122,661,716 | + |
| CDS | chr9 | 122,661,716 | 122,662,645 | + | ||
| 3UTR | chr9 | 122,662,645 | 122,662,648 | + | ||