OR2A1 Olfactory Receptor
| Gene Symbol | OR2A11 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | AC004889-A, OR7-19, HsOR7.6.23, ORL360 |
| External Ids | HGNC: 8229 GeneBank: AF399597, BK004418, NM_001005287 ORDB: ORL360 |
| Build #39 labels | OR2A1 |
| Chromosomal location | 7:144,318,125-144,319,054 (+) |
| Cluster | 7@144 |
| Synteny | CLIC#16 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2A42 | 100% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2A9 | 84% | 310 |
| Dog | OR2A9B | 83% | 310 |
| Mouse | Or2a20 | 80% | 310 |
| Rat | Or2a20 | 79% | 310 |
| Cow | OR2A5 | 79% | 307 |
| Orang | OR2A42 | 95% | 310 |
| Horse | OR2A9 | 86% | 310 |
| Horse | OR2A9BP | 83% | 309 |
| Chimp | OR2A42 | 97% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BX280997 |
| mRNA | AX721065 |
Sequence information
| Nucleotide sequence |
ATGGGGGAAAATCAGACAATGGTCACAGAGTTCCTCCTACTGGGATTTCTCCTGGGCCCA AGGATTCAGATGCTCCTCTTTGGGCTCTTCTCCCTGTTCTATATCTTCACCCTGCTGGGG AACGGGGCCATCCTGGGGCTCATCTCACTGGACTCCAGACTCCACACCCCCATGTACTTC TTCCTCTCACACCTGGCTGTCGTCGACATCGCCTACACCCGCAACACGGTGCCCCAGATG CTGGCGAACCTCCTGCATCCAGCCAAGCCCATCTCCTTTGCTGGCTGCATGACGCAGACC TTTCTCTGTTTGAGTTTTGGACACAGCGAATGTCTCCTGCTGGTGCTGATGTCCTACGAT CGTTACGTGGCCATCTGCCACCCTCTCCGATACTCCGTCATCATGACCTGGAGAGTCTGC ATCACCCTGGCCGTCACTTCCTGGACGTGTGGCTCCCTCCTGGCTCTGGCCCATGTGGTT CTCATCCTAAGACTGCCCTTCTCTGGGCCTCATGAAATCAACCACTTCTTCTGTGAAATC CTGTCTGTCCTCAGGCTGGCCTGTGCTGACACCTGGCTCAACCAGGTGGTCATCTTTGCA GCCTGCGTGTTCTTCCTGGTGGGGCCACCCAGCCTGGTGCTTGTCTCCTACTCGCACATC CTGGCGGCCATCCTGAGGATCCAGTCTGGGGAGGGCCGCAGAAAGGCCTTCTCCACCTGC TCCTCCCACCTCTGCGTGGTGGGACTCTTCTTTGGCAGTGCCATCATCATGTACATGGCC CCCAAGTCCCGCCATCCTGAGGAGCAGCAAAAGGTCTTTTTTCTATTTTACAGTTTTTTC AACCCAACACTTAACCCCCTGATTTACAGCCTGAGGAACGGAGAGGTCAAGGGTGCCCTG AGGAGAGCACTGGGCAAGGAAAGTCATTCC |
| Conceptual translation |
MGENQTMVTEFLLLGFLLGPRIQMLLFGLFSLFYIFTLLGNGAILGLISLDSRLHTPMYF FLSHLAVVDIAYTRNTVPQMLANLLHPAKPISFAGCMTQTFLCLSFGHSECLLLVLMSYD RYVAICHPLRYSVIMTWRVCITLAVTSWTCGSLLALAHVVLILRLPFSGPHEINHFFCEI LSVLRLACADTWLNQVVIFAACVFFLVGPPSLVLVSYSHILAAILRIQSGEGRRKAFSTC SSHLCVVGLFFGSAIIMYMAPKSRHPEEQQKVFFLFYSFFNPTLNPLIYSLRNGEVKGAL RRALGKESHS Protein domains and features |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 7 | 143,905,946 | 144,059,816 | CopyNumber | Variation_0726 (DGV), Variation_2110 (DGV) |
| 7 | 143,147,775 | 144,368,638 | CopyNumber | Variation_3708 (DGV) |
| 7 | 143,879,547 | 144,073,724 | CopyNumber | Variation_4571 (DGV) |
| 7 | 143,878,837 | 144,073,622 | CopyNumber | Variation_31398 (DGV) |
| 7 | 143,217,296 | 144,074,520 | CopyNumber | Variation_32962 (DGV) |
| 7 | 143,873,741 | 144,029,792 | Inversion | Variation_37282 (DGV) |
| 7 | 143,947,032 | 144,038,091 | Inversion | Variation_37283 (DGV) |
| 7 | 143,972,874 | 144,109,520 | Inversion | Variation_37284 (DGV) |
| 7 | 143,887,276 | 144,027,539 | CopyNumber | Variation_37567 (DGV) |
| 7 | 143,877,475 | 144,074,275 | CopyNumber | Variation_59622 (DGV) |
| 7 | 143,993,383 | 144,034,914 | CopyNumber | Variation_70057 (DGV) |
| 7 | 143,877,476 | 144,074,583 | CopyNumber | Variation_70058 (DGV) |
| 7 | 143,963,153 | 144,073,285 | CopyNumber | Variation_82244 (DGV), Variation_94944 (DGV) |
| 7 | 143,994,640 | 144,030,630 | CopyNumber | Variation_82245 (DGV) |
| 7 | 144,001,319 | 144,028,345 | CopyNumber | Variation_94945 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2A1.aApr07-unspliced | main_exon | 5UTR | chr7 | 144,317,856 | 144,318,125 | + |
| CDS | chr7 | 144,318,125 | 144,319,054 | + | ||
| 3UTR | chr7 | 144,319,054 | 144,319,057 | + | ||