OR2A7 Olfactory Receptor
| Gene Symbol | OR2A71 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.99 (pseudogene) |
| Aliases | HSDJ0798C17, OR7-18, OR7-20, HsOR7.6.21, ORL3181 |
| External Ids | HGNC: 8234 GeneBank: AF399598, BK004218, BK004610, NM_001005328 ORDB: ORL3181 |
| Build #39 labels | OR2A7 |
| Chromosomal location | 7:144,258,699-144,259,628 (-) |
| Cluster | 7@144 |
| Synteny | CLIC#16 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2A4 | 99.03% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2A25 | 78% | 308 |
| Mouse | Or2a7 | 82% | 310 |
| Rat | Or2a25 | 77% | 307 |
| Cow | OR2A7BP | 80% | 291 |
| Orang | OR2A7P | 93% | 310 |
| Horse | OR2A25 | 81% | 308 |
| Chimp | OR2A25 | 81% | 309 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | H62445 |
| mRNA | DQ786236 |
Sequence information
| Nucleotide sequence |
ATGGGGGACAATATAACATCCATCACAGAGTTCCTCCTACTGGGATTTCCCGTTGGCCCA AGGATTCAGATGCTCCTCTTTGGGCTCTTCTCCCTGTTCTACGTCTTCACCCTGCTGGGG AACGGGACCATACTGGGGCTCATCTCACTGGACTCCAGACTGCACGCCCCCATGTACTTC TTCCTCTCACACCTGGCGGTCGTCGACATCGCCTACGCCTGCAACACGGTGCCCCGGATG CTGGTGAACCTCCTGCATCCAGCCAAGCCCATCTCCTTTGCGGGCCGCATGATGCAGACC TTTCTGTTTTCCACTTTTGCTGTCACAGAATGTCTCCTCCTGGTGGTGATGTCCTATGAT CTGTACGTGGCCATCTGCCACCCCCTCCGATATTTGGCCATCATGACCTGGAGAGTCTGC ATCACCCTCGCGGTGACTTCCTGGACCACTGGAGTCCTTTTATCCTTGATTCATCTTGTG TTACTTCTACCTTTACCCTTCTGTAGGCCCCAGAAAATTTATCACTTTTTTTGTGAAATC TTGGCTGTTCTCAAACTTGCCTGTGCAGATACCCACATCAATGAGAACATGGTCTTGGCC GGAGCAATTTCTGGGCTGGTGGGACCCTTGTCCACAATTGTAGTTTCATATATGTGCATC CTCTGTGCTATCCTTCAGATCCAATCAAGGGAAGTTCAGAGGAAAGCCTTCTGCACCTGC TTCTCCCACCTCTGTGTGATTGGACTCTTTTATGGCACAGCCATTATCATGTATGTTGGA CCCAGATATGGGAACCCCAAGGAGCAGAAGAAATATCTCCTGCTGTTTCACAGCCTCTTT AATCCCATGCTCAATCCCCTTATCTGTAGTCTTAGGAACTCAGAAGTGAAGAATACTTTG AAGAGAGTGCTGGGAGTAGAAAGGGCTTTA |
| Conceptual translation |
MGDNITSITEFLLLGFPVGPRIQMLLFGLFSLFYVFTLLGNGTILGLISLDSRLHAPMYF FLSHLAVVDIAYACNTVPRMLVNLLHPAKPISFAGRMMQTFLFSTFAVTECLLLVVMSYD LYVAICHPLRYLAIMTWRVCITLAVTSWTTGVLLSLIHLVLLLPLPFCRPQKIYHFFCEI LAVLKLACADTHINENMVLAGAISGLVGPLSTIVVSYMCILCAILQIQSREVQRKAFCTC FSHLCVIGLFYGTAIIMYVGPRYGNPKEQKKYLLLFHSLFNPMLNPLICSLRNSEVKNTL KRVLGVERAL Protein domains and features |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 7 | 143,905,946 | 144,059,816 | CopyNumber | Variation_0726 (DGV), Variation_2110 (DGV) |
| 7 | 143,147,775 | 144,368,638 | CopyNumber | Variation_3708 (DGV) |
| 7 | 143,879,547 | 144,073,724 | CopyNumber | Variation_4571 (DGV) |
| 7 | 143,878,837 | 144,073,622 | CopyNumber | Variation_31398 (DGV) |
| 7 | 143,217,296 | 144,074,520 | CopyNumber | Variation_32962 (DGV) |
| 7 | 143,873,741 | 144,029,792 | Inversion | Variation_37282 (DGV) |
| 7 | 143,947,032 | 144,038,091 | Inversion | Variation_37283 (DGV) |
| 7 | 143,887,276 | 144,027,539 | CopyNumber | Variation_37567 (DGV) |
| 7 | 143,877,475 | 144,074,275 | CopyNumber | Variation_59622 (DGV) |
| 7 | 143,945,278 | 143,999,781 | Inversion | Variation_59845 (DGV) |
| 7 | 143,877,476 | 144,074,583 | CopyNumber | Variation_70058 (DGV) |
| 7 | 143,951,590 | 143,963,081 | CopyNumber | Variation_70060 (DGV) |
| 7 | 143,884,187 | 143,962,488 | CopyNumber | Variation_70061 (DGV) |
| 7 | 143,875,423 | 143,961,876 | CopyNumber | Variation_82237 (DGV), Variation_94936 (DGV) |
| 7 | 143,910,318 | 143,961,876 | CopyNumber | Variation_82238 (DGV) |
| 7 | 143,952,454 | 143,961,876 | CopyNumber | Variation_82243 (DGV) |
| 7 | 143,910,426 | 143,961,876 | CopyNumber | Variation_94938 (DGV) |
| CopyNumber | 204 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T239S | % Freq | CORP | |
|---|---|---|---|
| 1 | T | 99.23 | 0.997 |
| 2 | S | 0.77 | 0.999 |