OR2G3 Olfactory Receptor
| Gene Symbol | OR2G31 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | 0.2 (functional) |
| Aliases | OR1-33, HsOR1.5.5, ORL3043 |
| External Ids | HGNC: 15008 GeneBank: AB065622, BK004417, NM_001001914 ORDB: ORL3043 |
| Build #39 labels | OR2G3 |
| Chromosomal location | 1:247,605,586-247,606,512 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2B8P | 63.46% | 301 |
| OR2G2 | 62.95% | 305 |
| OR2W6P | 63.12% | 301 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2G3P | 83% | 309 |
| Mouse | Or2c1 | 62% | 306 |
| Rat | Or2w6 | 64% | 304 |
| Cow | OR2G6 | 66% | 308 |
| Orang | OR2G6 | 66% | 304 |
| Horse | OR2G28 | 66% | 305 |
| Chimp | OR2G6P | 65% | 301 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136712 |
| GNF Atlas2 | gnf1h10914_at |
Sequence information
| Nucleotide sequence |
ATGGGATTGGGCAATGAGAGTTCCCTAATGGATTTCATCCTTCTAGGCTTCTCAGACCAC CCTCGTCTGGAGGCTGTTCTCTTTGTATTTGTCCTTTTCTTCTACCTCCTGACCCTTGTG GGAAACTTCACCATAATCATCATCTCATATCTGGATCCCCCTCTTCATACCCCAATGTAC TTTTTTCTCAGCAACCTCTCTTTACTGGACATCTGCTTCACTACTAGCCTTGCTCCTCAG ACCTTAGTTAACTTGCAAAGACCAAAGAAGACGATCACTTACGGTGGTTGTGTGGCGCAA CTCTATATTTCTCTGGCACTGGGCTCCACTGAATGTATCCTCTTGGCTGACATGGCCTTG GATCGGTACATTGCTGTCTGCAAACCCCTCCACTATGTAGTCATCATGAACCCACGGCTT TGCCAACAGCTGGCATCTATCTCCTGGCTCAGTGGTTTGGCTAGTTCCCTAATCCATGCA ACTTTTACCTTGCAATTGCCTCTCTGTGGCAACCATAGGCTGGACCATTTTATTTGCGAA GTACCAGCTCTTCTCAAGTTGGCTTGTGTGGACACCACTGTCAATGAATTGGTGCTTTTT GTTGTTAGTGTTCTGTTTGTTGTCATTCCACCAGCACTCATCTCCATCTCCTATGGCTTC ATAACTCAAGCTGTGCTGAGGATCAAATCAGTAGAGGCAAGGCACAAAGCCTTCAGCACC TGCTCCTCCCACCTTACAGTGGTGATTATATTCTATGGCACCATAATCTACGTGTACCTG CAACCTAGTGACAGCTATGCCCAGGACCAAGGGAAGTTTATCTCCCTCTTCTACACCATG GTGACCCCCACTTTAAATCCTATCATCTATACTTTAAGGAACAAGGATATGAAAGAGGCT CTGAGGAAACTTCTCTCGGGAAAATTG |
| Conceptual translation |
MGLGNESSLMDFILLGFSDHPRLEAVLFVFVLFFYLLTLVGNFTIIIISYLDPPLHTPMY FFLSNLSLLDICFTTSLAPQTLVNLQRPKKTITYGGCVAQLYISLALGSTECILLADMAL DRYIAVCKPLHYVVIMNPRLCQQLASISWLSGLASSLIHATFTLQLPLCGNHRLDHFICE VPALLKLACVDTTVNELVLFVVSVLFVVIPPALISISYGFITQAVLRIKSVEARHKAFST CSSHLTVVIIFYGTIIYVYLQPSDSYAQDQGKFISLFYTMVTPTLNPIIYTLRNKDMKEA LRKLLSGKL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | C/T | P/S | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | C/T | H/H | 1000GP (YRI) |
| 1 | 247,605,760 | 247,605,760 | NS | A/G | M/V | 1000GP (CEU) |
| 1 | 247,605,915 | 247,605,915 | SYN | T/G | T/T | 1000GP (CEU) |
| 1 | 247,606,290 | 247,606,290 | SYN | C/T | H/H | 1000GP (CEU, CHBJPT) |
| 1 | 247,606,450 | 247,606,450 | NS | A/G | I/V | 1000GP (CEU, CHBJPT) |
| 1 | 247,768,948 | 247,768,948 | NS | C/T | P/S | rs61751929 (DbSNP) |
| 1 | 247,769,062 | 247,769,062 | NS | A/G | M/V | rs61748963 (DbSNP) |
| 1 | 247,769,217 | 247,769,217 | SYN | G/T | T/T | rs61750030 (DbSNP) |
| 1 | 247,769,378 | 247,769,378 | NS | C/T | S/L | rs6658792 (DbSNP) |
| 1 | 247,769,419 | 247,769,419 | NS | A/G | I/V | rs61740146 (DbSNP) |
| 1 | 247,769,425 | 247,769,425 | NS | A/G | K/E | rs56795889 (DbSNP) |
| 1 | 247,769,430 | 247,769,430 | SYN | A/T | V/V | rs61740141 (DbSNP) |
| 1 | 247,769,573 | 247,769,573 | NS | A/T | K/I | rs61744523 (DbSNP) |
| 1 | 247,769,592 | 247,769,592 | SYN | C/T | H/H | rs1151683 (DbSNP) |
| 1 | 247,769,659 | 247,769,659 | NS | A/G | M/V | rs12072304 (DbSNP) |
| 1 | 247,769,752 | 247,769,752 | NS | A/G | I/V | rs61730407 (DbSNP) |
| 1 | 247,769,786 | 247,769,786 | NS | A/C | D/A | rs61737569 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
| 1 | 247,714,585 | 248,277,146 | CopyNumber | Variation_3339 (DGV) |
| 1 | 247,753,207 | 248,376,070 | CopyNumber | Variation_8353 (DGV) |
| 1 | 247,753,334 | 248,322,316 | CopyNumber | Variation_2358 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| P21S | S49* | M59V | N65K | L164S | E180K | K229I | V258M | I289V | N294I | A300D | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | P | S | M | N | L | E | K | V | I | N | A | 53.76 | 0.281 |
| 2 | P | S | M | N | L | E | K | V | V | N | A | 31.87 | 0.281 |
| 3 | P | S | V | N | L | E | K | V | V | N | A | 5.30 | 0.765 |
| 4 | S | S | M | N | L | E | K | M | I | N | A | 2.53 | 0.281 |
| 5 | P | S | M | N | L | E | K | M | I | N | A | 2.30 | 0.281 |
| 6 | P | S | M | N | L | K | K | V | I | N | A | 1.46 | 0.281 |
| 7 | P | S | M | N | L | E | K | V | I | N | D | 1.46 | 0.281 |
| 8 | P | S | M | N | L | K | I | V | I | N | A | 0.61 | 0.281 |
| 9 | P | S | M | K | L | E | K | V | I | N | A | 0.31 | 0.281 |
| 10 | S | S | M | N | S | E | K | M | I | N | A | 0.15 | 0.281 |
| 11 | P | S | M | N | L | K | K | V | I | I | A | 0.08 | 0.281 |
| 12 | P | S | M | N | L | E | K | V | I | I | A | 0.08 | 0.281 |
| 13 | P | * | M | N | L | E | K | V | I | N | D | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2G3.aApr07-unspliced | main_exon | CDS | chr1 | 247,605,586 | 247,606,512 | + |
| 3UTR | chr1 | 247,606,512 | 247,606,515 | + | ||