OR2L13 Olfactory Receptor
| Gene Symbol | OR2L131 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | L |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | HsOR1.5.27 |
| External Ids | HGNC: 19578 GeneBank: BC028158, CR599101, NM_175911 |
| Build #39 labels | OR2L13, OR2L14 |
| Chromosomal location | 1:248,099,376-248,100,311 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2L1P | 72.61% | 303 |
| OR2L2 | 72.61% | 303 |
| OR2L3 | 72.28% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2L5 | 70% | 311 |
| Mouse | Or2l13 | 84% | 311 |
| Mouse | Or2l13b | 84% | 311 |
| Rat | Or2l13 | 84% | 311 |
| Rat | Or2l13d | 83% | 311 |
| Rat | Or2l13c | 83% | 311 |
| Cow | OR2L3 | 73% | 303 |
| Orang | OR2L13E | 95% | 312 |
| Orang | OR2L13F | 92% | 312 |
| Horse | OR2L5JP | 73% | 303 |
| Chimp | OR2L2 | 72% | 309 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DV080104 |
| mRNA | HQ447997 |
Sequence information
| Nucleotide sequence |
ATGGAGAAATGGAATCACACTTCAAATGATTTCATTTTGTTGGGTCTGCTTCCCCCAAAT CAAACTGGAATATTTCTCTTGTGCCTTATCATCCTCATATTCTTTCTGGCCTCGGTGGGT AACTCGGCCATGATTCACCTCATCCACGTGGATCCTCGTCTCCACACACCGATGTACTTT CTTCTCAGCCAGCTCTCCCTTATGGACCTGATGTACATCTCCACCACCGTCCCCAAGATG GCGTACAACTTCCTGTCCGGCCAGAAAGGCATCTCCTTCCTGGGATGTGGTGTGCAAAGC TTCTTCTTCCTGACCATGGCGTGTTCTGAAGGCTTACTCCTGACCTCCATGGCCTACGAC CGTTATTTGGCCATCTGCCACTCTCTCTATTATCCTATCCGCATGAGTAAAATGATGTGT GTGAAGATGATTGGAGGCTCTTGGACACTGGGGTCCATCAACTCCTTGGCACACACAGTC TTTGCCCTTCATATTCCCTACTGCAGGTCTAGGGCTATTGACCATTTCTTCTGCGATGTC CCAGCCATGTTGCTTCTTGCCTGTACAGATACTTGGGTCTATGAATATATGGTTTTTGTA AGTACAAGCCTCTTTCTCCTTTTCCCTTTCATTGGCATCACTTCTTCCTGTGGCCGAGTC CTATTTGCTGTCTATCATATGCACTCAAAGGAGGGGAGAAAAAAGGCCTTCACCACCATT TCAACACATTTAACTGTAGTGATCTTTTACTATGCACCTTTTGTCTACACCTATCTTCGG CCCAGGAATCTCCGCTCACCAGCTGAAGACAAGATCCTGGCAGTCTTCTACACCATCCTT ACCCCCATGCTCAATCCCATTATCTACAGCCTGAGGAATAAGGAAGTCCTGGGGGCTATG AGGAGAGTGTTTGGGATATTCTCTTTCCTGAAAGAA |
| Conceptual translation |
MEKWNHTSNDFILLGLLPPNQTGIFLLCLIILIFFLASVGNSAMIHLIHVDPRLHTPMYF LLSQLSLMDLMYISTTVPKMAYNFLSGQKGISFLGCGVQSFFFLTMACSEGLLLTSMAYD RYLAICHSLYYPIRMSKMMCVKMIGGSWTLGSINSLAHTVFALHIPYCRSRAIDHFFCDV PAMLLLACTDTWVYEYMVFVSTSLFLLFPFIGITSSCGRVLFAVYHMHSKEGRKKAFTTI STHLTVVIFYYAPFVYTYLRPRNLRSPAEDKILAVFYTILTPMLNPIIYSLRNKEVLGAM RRVFGIFSFLKE Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,263,471 | 248,263,471 | NS | A/G | H/R | rs45577033 (DbSNP) |
| 1 | 248,262,984 | 248,262,984 | NS | C/T | L/F | rs12727564 (DbSNP) |
| 1 | 248,263,495 | 248,263,495 | NS | G/T | R/L | rs74153072 (DbSNP) |
| 1 | 248,263,145 | 248,263,145 | NS | G/T | L/F | rs12742561 (DbSNP) |
| 1 | 248,262,941 | 248,262,941 | SYN | A/G | Q/Q | rs12738485 (DbSNP) |
| 1 | 248,262,983 | 248,262,983 | SYN | C/T | F/F | rs12753704 (DbSNP) |
| 1 | 248,100,169 | 248,100,169 | NS | G/A | R/H | 1000GP (CEU) |
| 1 | 100 | -100 | NS | C/T | T/I | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,753,334 | 248,322,316 | CopyNumber | Variation_2358 (DGV) |
| 1 | 247,714,585 | 248,277,146 | CopyNumber | Variation_3339 (DGV) |
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
| 1 | 247,753,207 | 248,376,070 | CopyNumber | Variation_8353 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 247,849,473 | 248,277,638 | CopyNumber | Variation_48302 (DGV) |
| 1 | 247,849,473 | 248,285,441 | CopyNumber | Variation_48303 (DGV) |
| 1 | 248,145,644 | 248,277,638 | CopyNumber | Variation_48304 (DGV) |
| 1 | 248,179,503 | 248,290,781 | CopyNumber | Variation_74987 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V50L | T257I | R265H | L273R | M283V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | V | T | R | L | M | 90.02 | 1.000 |
| 2 | V | T | R | R | M | 6.53 | 1.000 |
| 3 | V | I | R | L | M | 1.69 | 1.000 |
| 4 | V | T | H | L | M | 1.08 | 1.000 |
| 5 | V | T | R | L | V | 0.46 | 1.000 |
| 6 | L | T | R | L | M | 0.23 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2L13.aApr07 | exon_5UTR | chr1 | 247,937,191 | 247,937,384 | + | |
| exon_5UTR | chr1 | 248,098,651 | 248,098,775 | + | ||
| main_exon | 5UTR | chr1 | 248,099,358 | 248,099,376 | + | |
| CDS | chr1 | 248,099,376 | 248,100,311 | + | ||
| 3UTR | chr1 | 248,100,311 | 248,100,995 | + | ||
| OR2L13.bApr07 | exon_5UTR | chr1 | 247,937,023 | 247,937,384 | + | |
| main_exon | 5UTR | chr1 | 248,099,358 | 248,099,376 | + | |
| CDS_partial | chr1 | 248,099,376 | 248,099,972 | + | ||
| exon_3UTR | chr1 | 248,115,375 | 248,115,466 | + | ||