OR3A2 Olfactory Receptor
Gene Symbol | OR3A21 (View this gene in GeneCards) |
Family | 3 |
Subfamily | A |
Pseudogene | No |
CORP pseudogene probability score | 0.29 (functional) |
Aliases | OR17-15, OR17-228, OR17-14, HsOR17.1.10, ORL3746, ORL268 |
External Ids | HGNC: 8283 GeneBank: AF087930, BK004239, HSU04713, NM_002551, U86244 ORDB: ORL3746, ORL268 |
Build #39 labels | OR3A2 |
Chromosomal location | 17:3,277,973-3,278,917 (-) |
Cluster | 17@3b |
Synteny | CLIC#39 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR3A3 | 90.16% | 315 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR3A1H | 82% | 314 |
Dog | OR3A1 | 82% | 314 |
Mouse | Or3a1d | 78% | 314 |
Rat | Or3a1e | 77% | 313 |
Cow | OR3A2B | 85% | 315 |
Orang | OR3A3 | 85% | 315 |
Horse | OR3A2D | 84% | 315 |
Horse | OR3A2E | 83% | 315 |
Horse | OR3A1 | 82% | 314 |
Chimp | OR3A3 | 84% | 315 |
Chimp | OR3A1 | 82% | 314 |
Expression evidences
Source | Accession |
---|---|
ESTs | DN693319 |
mRNA | BC095517 |
GNF Atlas2 | 221386_at |
Sequence information
Nucleotide sequence |
ATGGAGCCAGAAGCTGGGACCAATAGGACCGCTGTTGCTGAGTTCATTCTACTGGGCCTA GTGCAAACAGAAGAGATGCAGCCAGTTGTCTTTGTGCTCCTCCTCTTTGCCTATCTGGTC ACAACTGGGGGCAACCTCAGCATCCTGGCAGCCGTCTTGGTGGAGCCCAAACTCCACGCC CCCATGTACTTCTTCCTGGGGAACCTGTCAGTGCTGGATGTCGGATGTATCACTGTCACT GTTCCTGCAATGTTGGGTCGTCTCTTGTCCCACAAGTCCACAATTTCCTATGACGCCTGC CTCTCCCAGCTCTTCTTCTTCCACCTTCTGGCTGGGATGGACTGCTTCCTGCTGACCGCC ATGGCCTATGACCGACTCCTGGCCATCTGCCAGCCCCTCACCTACAGCACCCGCATGAGT CAGACAGTCCAGAGGATGTTGGTGGCTGCGTCCTTGGCTTGTGCCTTCACCAACGCACTG ACCCACACTGTGGCCATGTCCACGCTCAACTTCTGTGGCCCCAATGAGGTCAATCACTTC TACTGTGACCTCCCACAGCTCTTCCAGCTCTCCTGCTCCAGCACCCAACTCAATGAGCTG CTGCTCTTTGCTGTGGGTTTCATCATGGCAGGCACACCTTTGGTTCTCATCATCACTGCC TACAGCCACGTGGCAGCTGCAGTTCTACGAATCCGTTCAGTGGAGGGCCGAAAGAAGGCC TTCTCCACGTGTGGCTCCCACCTCACCGTGGTTTGTCTTTTCTTTGGAAGAGGTATCTTC AACTACATGAGACTGGGTTCAGAGGAGGCTTCAGACAAGGATAAAGGGGTTGGAGTTTTC AACACTGTTATCAACCCTATGCTGAACCCTCTTATCTACAGCCTCAGAAACCCTGATGTT CAGGGTGCTCTGTGGCAAATATTTTTGGGGAGGAGATCACTGACC |
Conceptual translation |
MEPEAGTNRTAVAEFILLGLVQTEEMQPVVFVLLLFAYLVTTGGNLSILAAVLVEPKLHA PMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTA MAYDRLLAICQPLTYSTRMSQTVQRMLVAASLACAFTNALTHTVAMSTLNFCGPNEVNHF YCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPLVLIITAYSHVAAAVLRIRSVEGRKKA FSTCGSHLTVVCLFFGRGIFNYMRLGSEEASDKDKGVGVFNTVINPMLNPLIYSLRNPDV QGALWQIFLGRRSLT Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
17 | 100 | -100 | SYN | G/A | H/H | 1000GP (YRI, YRI) |
17 | 3,181,284 | 3,181,284 | NS | A/C | W/G | rs61729398 (DbSNP) |
17 | 3,181,356 | 3,181,356 | NS | C/G | A/P | rs61742213 (DbSNP) |
17 | 3,181,384 | 3,181,384 | SYN | T/C | G/G | rs769434 (DbSNP) |
17 | 3,181,555 | 3,181,555 | SYN | A/G | T/T | rs2013809 (DbSNP) |
17 | 3,181,644 | 3,181,644 | NS | C/G | V/L | rs61734039 (DbSNP) |
17 | 3,181,662 | 3,181,662 | NS | C/G | V/L | rs9901356 (DbSNP) |
17 | 3,181,677 | 3,181,677 | NS | C/G | D/H | rs73977611 (DbSNP) |
17 | 3,182,087 | 3,182,087 | NS | A/G | I/T | rs62089500 (DbSNP) |
17 | 3,277,990 | 3,277,990 | NS | C/A | G/W | 1000GP (CEU) |
17 | 3,278,090 | 3,278,090 | SYN | C/T | G/G | 1000GP (CEU, CHBJPT) |
17 | 3,278,261 | 3,278,261 | SYN | A/G | T/T | 1000GP (CEU) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
CopyNumber | 41 (Hasin) | |||
17 | 3,179,267 | 3,182,311 | Deletion | #242 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
G316W | P292A | L196V | % Freq | CORP | |
---|---|---|---|---|---|
1 | G | P | L | 94.64 | 0.203 |
2 | G | P | V | 3.28 | 0.203 |
3 | W | P | L | 1.20 | 0.203 |
4 | G | A | L | 0.88 | 0.203 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR3A2.aApr07 | main_exon | 3UTR | chr17 | 3,277,693 | 3,277,973 | - |
CDS | chr17 | 3,277,973 | 3,278,917 | - | ||
5UTR | chr17 | 3,278,917 | 3,278,923 | - | ||
exon_5UTR | chr17 | 3,279,076 | 3,279,153 | - | ||
exon_5UTR | chr17 | 3,336,033 | 3,336,126 | - | ||
exon_5UTR | chr17 | 3,383,804 | 3,383,899 | - | ||
exon_5UTR | chr17 | 3,386,125 | 3,386,292 | - | ||
OR3A2.bApr07-unspliced | main_exon | 3UTR | chr17 | 3,277,890 | 3,277,973 | - |
CDS | chr17 | 3,277,973 | 3,278,917 | - | ||
5UTR | chr17 | 3,278,917 | 3,278,974 | - |