OR3A3 Olfactory Receptor
| Gene Symbol | OR3A31 (View this gene in GeneCards) |
| Family | 3 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.09 (functional) |
| Aliases | OR17-16, OR17-137, OR17-201, OR5-83, OR17-22, HsOR17.1.15, ORL1015, ORL1025 |
| External Ids | HGNC: 8284 GeneBank: AF087926, AF399620, AF546420-AF546433, BC069415, BK004236, HSU04688, NM_012373, U86243, U86245, U86272 ORDB: ORL1015, ORL1025 |
| Build #39 labels | OR3A3, OR3A8P |
| Chromosomal location | 17:3,420,586-3,421,530 (+) |
| Cluster | 17@3b |
| Synteny | CLIC#39 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR3A2 | 90.16% | 315 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR3A1H | 82% | 314 |
| Dog | OR3A2 | 81% | 315 |
| Mouse | Or3a1d | 79% | 314 |
| Rat | Or3a1e | 75% | 313 |
| Cow | OR3A2 | 82% | 314 |
| Cow | OR3A1D | 82% | 313 |
| Cow | OR3A2B | 81% | 315 |
| Orang | OR3A2 | 85% | 285 |
| Horse | OR3A2 | 82% | 315 |
| Horse | OR3A2E | 81% | 315 |
| Horse | OR3A2D | 81% | 315 |
| Chimp | OR3A2 | 88% | 315 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC108921 |
| GNF Atlas2 | 221426_s_at |
Sequence information
| Nucleotide sequence |
ATGGAGCCAGAAGCTGGGACCAATAGGACCGCTGTTGCTGAGTTCATTCTACTGGGCCTA GTGCAAACAGAAGAGATGCAGCCAGTTGTCTTTGTGCTCCTCCTCTTTGCCTATCTGGTC ACAACTGGGGGCAACCTCAGCATCCTGGCAGCCGTCTTGGTGGAGCCCAAACTCCACGCC CCCATGTACTTCTTCCTGGGGAACCTGTCAGTGCTGGATGTCGGATGTATCACTGTCACT GTTCCTGCAATGTTGGGTCGTCTCTTGTCCCACAAGTCCACAATTTCCTATGACGCCTGC CTCTCCCAGCTCTTCTTCTTCCACCTTCTGGCTGGGATGGACTGCTTCCTGCTGACCGCC ATGGCCTATGACCGACTCCTGGCCATCTGCCAGCCCCTCACCTACAGCACCCGCATGAGT CAGACAGTCCAGAGGATGTTGGTGGCTGCGTCCTGGGCTTGTGCCTTCACCAACGCACTG ACCCACACTGTGGCCATGTCCACGCTCAACTTCTGTGGCCCCAATGAGGTCAATCACTTC TACTGTGACCTCCCACAGCTCTTCCAGCTCTCCTGCTCCAGCACCCAACTCAATGAGCTG CTGCTCTTTGTAGCAGCAGCCTTCATGGCTGTGGCACCCTTGGTCTTCATCAGTGTGTCC TATGCCCATGTGGTAGCTGCTGTGCTGCAAATCCGCTCTGCTGAGGGCAGAAAGAAGGCC TTCTCCACATGTGGCTCCCACCTCACTGTGGTGGGCATCTTCTATGGGACAGGTGTCTTC AGCTACATGAGGCTGGGTTCAGTGGAATCTTCAGACAAGGATAAGGGGGTTGGGGTTTTC ATGACTGTGATCAACCCCATGCTGAACCCACTTATCTACAGCCTCAGAAATACTGATGTT CAGGGCGCTCTGTGTCAGCTACTTGTGGGGAAGCGATCACTGACC |
| Conceptual translation |
MEPEAGTNRTAVAEFILLGLVQTEEMQPVVFVLLLFAYLVTTGGNLSILAAVLVEPKLHA PMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTA MAYDRLLAICQPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNEVNHF YCDLPQLFQLSCSSTQLNELLLFVAAAFMAVAPLVFISVSYAHVVAAVLQIRSAEGRKKA FSTCGSHLTVVGIFYGTGVFSYMRLGSVESSDKDKGVGVFMTVINPMLNPLIYSLRNTDV QGALCQLLVGKRSLT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 17 | 100 | -100 | NS | A/G | M/V | 1000GP (YRI, YRI) |
| 17 | 3,324,086 | 3,324,086 | SYN | A/G | L/L | rs227788 (DbSNP) |
| 17 | 3,324,255 | 3,324,255 | NS | C/T | L/F | rs769432 (DbSNP) |
| 17 | 3,324,334 | 3,324,334 | NS | T/G | L/W | rs916039 (DbSNP) |
| 17 | 3,324,720 | 3,324,720 | NS | A/G | M/V | rs12939997 (DbSNP) |
| 17 | 3,324,810 | 3,324,810 | NS | G/A | E/K | rs227787 (DbSNP) |
| 17 | 3,421,426 | 3,421,426 | NS | A/G | M/V | 1000GP (CEU) |
| 17 | 3,421,516 | 3,421,516 | NS | A/G | K/E | 1000GP (CEU, CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 219 (Hasin) | |||
| 17 | 3,323,780 | 3,326,824 | CopyNumber | #142 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| H223Q | R232H | M281V | K311E | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | H | R | M | K | 67.43 | 0.053 |
| 2 | H | R | M | E | 28.96 | 0.053 |
| 3 | H | R | V | K | 3.30 | 0.053 |
| 4 | Q | R | M | K | 0.08 | 0.053 |
| 5 | H | R | V | E | 0.08 | 0.053 |
| 6 | H | H | M | E | 0.08 | 0.053 |
| 7 | H | H | M | K | 0.08 | 0.053 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR3A3.aApr07-unspliced | main_exon | 5UTR | chr17 | 3,420,568 | 3,420,586 | + |
| CDS | chr17 | 3,420,586 | 3,421,530 | + | ||
| 3UTR | chr17 | 3,421,530 | 3,421,533 | + | ||