OR4A8P Olfactory Receptor
| Gene Symbol | OR4A8P1 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | A |
| Pseudogene | Yes |
| CORP pseudogene probability score | |
| Aliases | OR11-110, HsOR11.10.4P, ORL3587 |
| External Ids | HGNC: 15165 GeneBank: AF546448-AF546461, BK004702, NG_004235 ORDB: ORL3587 |
| Build #39 labels | OR4A8P |
| Chromosomal location | 11:54,682,876-54,683,820 (-) |
| Cluster | 11@51 |
| Synteny | CLIC#26 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP T->C at position 406 (AA change= */R ) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4A11P | 83.67% | 300 |
| OR4A40P | 87.94% | 315 |
| OR4A45P | 79.93% | 304 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4A39 | 72% | 312 |
| Mouse | Or4a39 | 72% | 308 |
| Rat | Or4a77c | 69% | 312 |
| Cow | OR4A2 | 67% | 299 |
| Orang | OR4A47P | 64% | 299 |
| Horse | OR4A124 | 74% | 299 |
| Chimp | OR4A40 | 82% | 315 |
| Chimp | OR4A40CP | 83% | 300 |
Sequence information
| Nucleotide sequence |
ATGAGGCAGAATAACAATATTACAGAATTTGTCCTCCTGGGCTTCTCTCAGTATCCTGAT GTGCAAAATGCATTATTTGTCATGTTTTTACTCATATATATTGTGACTATGGTGGGGAAC CTGCTCATTGTGGTGTCTATTATTGCCAGTCCCTTTTTGGGCTCCCCAGTGTACTTCTTC CTTGCCTGCCTGTCATTTATAGATGCTGTGTATTCCACCACCATTTCTCCTGTATTGATT GTAGACTTACTCTGTGATAAAAAGACTATTTCCTTCCCAGCTTGCATGGGTCAGCTATTT ATAGAGCACTTGTTTGGTGATACTGACGTCTTCCTTCTGGTGGTGATGGCCTATGATCGC TACGTGGCCACCTGTAAGCCACTGCGCTATTTGACCATCATGAATTGACAGGTTTGCATC CTTCTGTTGGTGGTGGCTGTGACTGGAGGTTTTCTGCATTCTGTGTTTCAAATTTTAGTT GTGTACAGTCTCCCTTTCTGTGGCCCCAATGTCATTTATCACTTTTTCTGTAACATATAC CCTTTATTGGACCTGGAATGCACTGACACCTACTTCGTAGGCCTCGCTGTGGTTTTCAAT GGTGGAGCAATCTGTATGGTCATCTTCACCCTTCTACTAATCTCCTATGGGGTCATCCTA AACTCCCTTAAAACTTATAGTCCGGAAGGGAGGCATAAAGCTCCGTTTATCTGCAGCTCC CACTTTATCATGGTTATCTTGTTTTTTGTTCCCTGTATTTTCTTATATGTTAGACCCGTT TCAAACTTTCCTATTGATAAATTCCTGACTGTGTTTTATTCAGTTATCACACCCAAGTTG AATCCTTTTATATACATGTTGAGAAATTCAGAGATGAGAAATGCTATAGAAAATCTCTTG GGATACCAAAGTGGGAAGACAGGATTTAGATGCTCCAAGCTCAAT |
| Conceptual translation |
MRQNNNITEFVLLGFSQYPDVQNALFVMFLLIYIVTMVGNLLIVVSIIASPFLGSPVYFF LACLSFIDAVYSTTISPVLIVDLLCDKKTISFPACMGQLFIEHLFGDTDVFLLVVMAYDR YVATCKPLRYLTIMNXVCILLLVVAVTGGFLHSVFQILVVYSLPFCGPNVIYHFFCNIY PLLDLECTDTYFVGLAVVFNGGAICMVIFTLLLISYGVILNSLKTYSPEGRHKAPFICSS HFIMVILFFVPCIFLYVRPVSNFPIDKFLTVFYSVITPKLNPFIYMLRNSEMRNAIENLL GYQSGKTGFRCSKLN Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | SNP | A/T | 1000GP (YRI, YRI, YRI) | |
| 11 | 51,435,510 | 51,435,510 | SNP | A/T | rs485548 (DbSNP) | |
| 11 | 51,435,848 | 51,435,847 | Ins(1) | -/A | rs34678533 (DbSNP) | |
| 11 | 51,435,852 | 51,435,852 | SNP | G/T | rs539871 (DbSNP) | |
| 11 | 51,435,866 | 51,435,866 | SNP | A/G | rs61891402 (DbSNP) | |
| 11 | 51,436,215 | 51,436,215 | SNP | A/G | rs1846261 (DbSNP) | |
| 11 | 54,682,916 | 54,682,916 | SNP | C/A | 1000GP (CEU) | |
| 11 | 54,683,413 | 54,683,413 | SNP | A/G | 1000GP (CEU) | |
| 11 | 54,683,427 | 54,683,427 | SNP | G/T | 1000GP (CEU) | |
| 11 | 54,683,464 | 54,683,464 | SNP | C/T | 1000GP (CEU) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 51,192,824 | 51,563,636 | CopyNumber | Variation_8689 (DGV) |
| 11 | 51,228,146 | 51,525,878 | CopyNumber | Variation_48823 (DGV) |
| 11 | 51,372,036 | 51,529,002 | CopyNumber | Variation_53111 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.