OR4C11 Olfactory Receptor

Gene Symbol	OR4C11¹ (View this gene in GeneCards)
Family	4
Subfamily	C
Pseudogene	No
CORP pseudogene probability score	0.12 (functional)
Aliases	OR11-136, HsOR11.11.17
External Ids	HGNC: 15167 GeneBank: AB065774, BK004503, NM_001004700
Build #39 labels	OR4C11P
Chromosomal location	11:55,603,444-55,604,373 (-)
Cluster	11@56
Synteny	CLIC#26
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol	Percent	Length
OR4C16	67.31%	309

Most Similar ORs in other species (Orthologs)

Specie	Symbol	Percent	Length
Dog	OR4C11E	92%	309
Dog	OR4C11I	91%	309
Mouse	Or4c11	89%	307
Rat	Or4c11	90%	307
Cow	OR4C156P	76%	309
Orang	OR4C9P	56%	309
Horse	OR4C11E	83%	309
Chimp	OR4C31	75%	304

Expression evidences

Source	Accession
mRNA	BC140727
GNF Atlas2	gnf1h10928_at

Sequence information

Nucleotide sequence

ATGCAGCAAAATAACAGTGTGCCTGAATTCATACTGTTAGGATTAACACAGGATCCCTTG
AGGCAGAAAATAGTGTTTGTAATCTTCTTAATTTTCTATATGGGAACTGTGGTGGGGAAT
ATGCTCATTATTGTGACCATCAAGTCCAGCCGGACACTAGGAAGCCCCATGTACTTCTTT
CTATTTTATTTGTCCTTTGCAGATTCTTGCTTTTCAACTTCCACAGCCCCTAGATTAATT
GTGGATGCTCTCTCTGAAAAGAAAATTATAACCTACAATGAGTGCATGACACAAGTCTTT
GCACTACATTTATTTGGCTGCATGGAGATCTTTGTCCTCATTCTCATGGCTGTTGATCGC
TATGTGGCCATCTGTAAGCCCTTGCGTTACCCAACCATCATGAGCCAGCAGGTCTGCATC
ATCCTGATTGTTCTTGCCTGGATAGGGTCTTTAATACACTCTACAGCTCAGATTATCCTG
GCCTTAAGATTGCCTTTCTGTGGACCCTATTTGATTGATCATTATTGCTGTGATTTGCAG
CCCTTGTTGAAACTTGCCTGCATGGACACTTACATGATCAACCTGCTGTTGGTGTCTAAC
AGTGGGGCAATTTGCTCAAGTAGTTTCATGATTTTGATAATTTCATATATTGTCATCTTG
CATTCACTGAGAAACCACAGTGCCAAAGGGAAGAAAAAGGCTCTCTCCGCTTGCACGTCT
CACATAATTGTAGTCATCTTATTCTTTGGCCCATGTATATTCATATATACACGCCCCCCG
ACCACTTTCCCCATGGACAAGATGGTGGCAGTATTTTATACTATTGGAACACCCTTTCTC
AATCCACTCATCTACACACTGAGGAATGCAGAAGTGAAAAATGCCATGAGAAAGTTATGG
CATGGCAAAATTATTTCAGAAAACAAAGGA

Conceptual translation

MQQNNSVPEFILLGLTQDPLRQKIVFVIFLIFYMGTVVGNMLIIVTIKSSRTLGSPMYFF
LFYLSFADSCFSTSTAPRLIVDALSEKKIITYNECMTQVFALHLFGCMEIFVLILMAVDR
YVAICKPLRYPTIMSQQVCIILIVLAWIGSLIHSTAQIILALRLPFCGPYLIDHYCCDLQ
PLLKLACMDTYMINLLLVSNSGAICSSSFMILIISYIVILHSLRNHSAKGKKKALSACTS
HIIVVILFFGPCIFIYTRPPTTFPMDKMVAVFYTIGTPFLNPLIYTLRNAEVKNAMRKLW
HGKIISENKG

Protein domains and features

Variations - SNPs

Chr	Start	End	Type	Variation	AA Change	SNP IDs
11	55,371,285	55,371,284	Ins(1)	-/C		rs34651794 (DbSNP)
11	55,371,132	55,371,132	NS	A/T	S/T	rs7114415 (DbSNP)
11	55,371,807	55,371,807	NS	A/T	L/I	rs11230346 (DbSNP)
11	55,371,313	55,371,313	NS	C/A	L/F	rs61735721 (DbSNP)
11	55,371,410	55,371,410	NS	C/G	W/S	rs61732335 (DbSNP)
11	55,371,673	55,371,673	NS	C/G	L/F	rs61730928 (DbSNP)
11	55,371,699	55,371,699	NS	G/A	R/W	rs61730871 (DbSNP)
11	55,371,275	55,371,275	NS	G/A	T/M	rs61743011 (DbSNP)
11	55,371,021	55,371,021	NS	G/T	P/T	rs2456022 (DbSNP)
11	55,371,828	55,371,828	NS	G/T	P/T	rs491160 (DbSNP)
11	55,371,747	55,371,747	NS	T/C	R/G	rs61737219 (DbSNP)
11	55,371,039	55,371,039	NS	T/C	I/V	rs61747888 (DbSNP)
11	55,603,905	55,603,905	nonsense SNP	G/A	Q/*	1000GP (CEU)
11	55,604,331	55,604,331	NS	A/T	L/I	1000GP (CEU, CHBJPT)
11	55,604,352	55,604,352	NS	G/T	P/T	1000GP (CEU)
11	55,603,656	55,603,656	NS	A/T	S/T	1000GP (CEU)
11	100	-100	NS	C/T	A/T	1000GP (YRI, YRI, YRI)

Variations - CNVs

Chr	Start	End	Type	Sources
11	55,153,930	55,816,828	CopyNumber	Variation_0308 (DGV)
11	55,359,025	55,470,359	CopyNumber	Variation_0419 (DGV), Variation_34977 (DGV)
11	55,371,807	55,373,703	CopyNumber	Variation_1890 (DGV)
11	55,339,702	55,638,112	CopyNumber	Variation_2926 (DGV)
11	55,222,420	55,621,884	CopyNumber	Variation_3852 (DGV)
11	55,367,167	55,452,993	CopyNumber	Variation_6923 (DGV)
11	54,835,623	55,879,426	CopyNumber	Variation_8690 (DGV)
11	55,371,021	55,422,586	CopyNumber	Variation_9662 (DGV), Variation_48831 (DGV)
11	55,360,213	55,447,427	CopyNumber	Variation_9663 (DGV), Variation_48827 (DGV)
11	55,371,021	55,447,427	CopyNumber	Variation_10359 (DGV), Variation_48834 (DGV), Variation_48835 (DGV)
11	55,371,021	55,418,182	CopyNumber	Variation_10361 (DGV), Variation_48830 (DGV), Variation_53101 (DGV)
11	55,364,237	55,431,910	Inversion	Variation_29474 (DGV)
11	55,360,213	55,447,426	CopyNumber	Variation_29606 (DGV)
11	55,371,020	55,460,788	CopyNumber	Variation_29910 (DGV)
11	55,367,884	55,459,183	CopyNumber	Variation_31823 (DGV)
11	55,362,651	55,460,561	CopyNumber	Variation_34978 (DGV)
11	55,358,496	55,434,466	CopyNumber	Variation_37484 (DGV)
11	55,368,154	55,450,788	CopyNumber	Variation_38972 (DGV)
11	55,365,425	55,431,552	CopyNumber	Variation_41253 (DGV)
11	55,335,878	55,453,486	CopyNumber	Variation_48051 (DGV)
11	55,360,213	55,442,368	CopyNumber	Variation_48826 (DGV)
11	55,360,213	55,470,003	CopyNumber	Variation_48828 (DGV)
11	55,371,021	55,408,700	CopyNumber	Variation_48829 (DGV)
11	55,371,021	55,437,126	CopyNumber	Variation_48832 (DGV)
11	55,371,021	55,442,368	CopyNumber	Variation_48833 (DGV)
11	55,371,021	55,460,095	CopyNumber	Variation_48836 (DGV)
11	55,339,829	55,447,427	CopyNumber	Variation_53140 (DGV)
11	55,360,213	55,490,377	CopyNumber	Variation_53507 (DGV)
11	55,360,213	55,460,788	CopyNumber	Variation_53994 (DGV)
11	55,360,213	55,470,994	CopyNumber	Variation_54018 (DGV)
11	55,364,677	55,453,061	CopyNumber	Variation_65955 (DGV)
11	55,366,131	55,452,023	CopyNumber	Variation_75644 (DGV)
11	55,365,707	55,452,023	CopyNumber	Variation_85779 (DGV)
			Deletion	252 (Hasin)
11	55,368,920	55,371,949	Deletion	#14 (Waszak)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

	V271I	S240T	A237T	M192T	Q157*	W147S	L15I	P8T	% Freq	CORP
1	V	S	A	M	Q	W	L	P	58.45	0.274
2	V	S	A	M	Q	W	I	P	27.11	0.274
3	V	S	A	M	*	W	L	P	5.45	1.200
4	V	T	A	M	Q	W	L	T	3.30	0.059
5	V	S	A	M	Q	S	L	P	2.53	0.274
6	V	S	A	M	Q	W	L	T	2.23	0.274
7	V	S	A	T	Q	W	L	T	0.46	0.274
8	I	S	A	M	Q	W	I	P	0.31	0.274
9	V	S	T	M	Q	W	L	P	0.15	0.093

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession	Type		Chr	Start	End	Strand
OR4C11.aApr07-unspliced	main_exon	3UTR	chr11	55,603,441	55,603,444	-
OR4C11.aApr07-unspliced	main_exon	CDS	chr11	55,603,444	55,604,373	-

HORDE

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