OR4C6 Olfactory Receptor
Gene Symbol | OR4C61 (View this gene in GeneCards) |
Family | 4 |
Subfamily | C |
Pseudogene | No |
CORP pseudogene probability score | 0.03 (functional) |
Aliases | OR11-138, HsOR11.11.20, ORL3425 |
External Ids | HGNC: 14743 GeneBank: AB065517, BK004330, CR593785, NM_001004704 ORDB: ORL3425 |
Build #39 labels | OR4C6 |
Chromosomal location | 11:55,665,167-55,666,093 (+) |
Cluster | 11@56 |
Synteny | CLIC#26 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR4C14P | 69.26% | 309 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR4C142P | 79% | 309 |
Mouse | Or4c102 | 78% | 302 |
Rat | Or4c102 | 77% | 302 |
Cow | OR4C163P | 68% | 313 |
Orang | OR4C9P | 61% | 302 |
Horse | OR4C6P | 82% | 309 |
Chimp | OR4C14P | 69% | 310 |
Expression evidences
Source | Accession |
---|---|
ESTs | BX330269 |
mRNA | AB463962 |
Sequence information
Nucleotide sequence |
ATGGAAAATCAAAACAATGTGACTGAATTCATTCTTCTGGGTCTCACAGAGAACCTGGAG CTGTGGAAAATATTTTCTGCTGTGTTTCTTGTCATGTATGTAGCCACAGTGCTGGAAAAT CTACTTATTGTGGTAACTATTATCACAAGTCAGAGTCTGAGGTCACCTATGTATTTTTTT CTTACCTTCTTGTCCCTTTTGGATGTCATGTTCTCATCTGTCGTTGCCCCCAAGGTGATT GTAGACACCCTCTCCAAGAGCACTACCATCTCTCTCAAAGGCTGCCTCACCCAGCTGTTT GTGGAGCATTTCTTTGGTGGTGTGGGGATCATCCTCCTCACTGTGATGGCCTATGACCGC TACGTGGCCATCTGTAAGCCCCTGCACTACACGATCATCATGAGTCCACGGGTGTGCTGC CTAATGGTAGGAGGGGCTTGGGTGGGGGGATTTATGCACGCAATGATACAACTTCTCTTC ATGTATCAAATACCCTTCTGTGGTCCTAATATCATAGATCACTTTATATGTGATTTGTTT CAGTTGTTGACACTTGCCTGCACGGACACCCACATCCTGGGCCTCTTAGTTACCCTCAAC AGTGGGATGATGTGTGTGGCCATCTTTCTTATCTTAATTGCGTCCTACACGGTCATCCTA TGCTCCCTGAAGTCTTACAGCTCTAAAGGGCGGCACAAAGCCCTCTCTACCTGCAGCTCC CACCTCACGGTGGTTGTATTGTTCTTTGTCCCCTGTATTTTCTTGTACATGAGGCCTGTG GTCACTCACCCCATAGACAAGGCAATGGCTGTGTCAGACTCAATCATCACACCCATGTTA AATCCCTTGATCTATACACTGAGGAATGCAGAGGTGAAAAGTGCCATGAAGAAACTCTGG ATGAAATGGGAGGCTTTGGCTGGGAAA |
Conceptual translation |
MENQNNVTEFILLGLTENLELWKIFSAVFLVMYVATVLENLLIVVTIITSQSLRSPMYFF LTFLSLLDVMFSSVVAPKVIVDTLSKSTTISLKGCLTQLFVEHFFGGVGIILLTVMAYDR YVAICKPLHYTIIMSPRVCCLMVGGAWVGGFMHAMIQLLFMYQIPFCGPNIIDHFICDLF QLLTLACTDTHILGLLVTLNSGMMCVAIFLILIASYTVILCSLKSYSSKGRHKALSTCSS HLTVVVLFFVPCIFLYMRPVVTHPIDKAMAVSDSIITPMLNPLIYTLRNAEVKSAMKKLW MKWEALAGK Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
11 | 55,432,668 | 55,432,668 | NS | A/C | E/A | rs61729625 (DbSNP) |
11 | 55,433,505 | 55,433,505 | NS | A/G | K/R | rs12363829 (DbSNP) |
11 | 55,433,040 | 55,433,040 | NS | C/T | T/I | rs11230600 (DbSNP) |
11 | 55,432,876 | 55,432,876 | SYN | A/G | K/K | rs61995720 (DbSNP) |
11 | 55,432,930 | 55,432,930 | SYN | C/G | L/L | rs61995737 (DbSNP) |
11 | 55,665,917 | 55,665,917 | NS | C/T | P/S | 1000GP (CEU) |
11 | 55,665,564 | 55,665,564 | NS | T/C | I/T | 1000GP (CEU, CHBJPT) |
11 | 55,665,914 | 55,665,914 | NS | G/T | V/F | 1000GP (CHBJPT) |
11 | 100 | -100 | SYN | C/T | T/T | 1000GP (YRI) |
11 | 100 | -100 | NS | T/C | I/T | 1000GP (YRI, YRI) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
11 | 55,359,025 | 55,470,359 | CopyNumber | Variation_0419 (DGV), Variation_34977 (DGV) |
11 | 55,339,702 | 55,638,112 | CopyNumber | Variation_2926 (DGV) |
11 | 55,222,420 | 55,621,884 | CopyNumber | Variation_3852 (DGV) |
11 | 55,382,681 | 55,548,038 | CopyNumber | Variation_4743 (DGV) |
11 | 55,367,167 | 55,452,993 | CopyNumber | Variation_6923 (DGV) |
11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
11 | 55,377,006 | 55,620,699 | CopyNumber | Variation_9188 (DGV) |
11 | 55,360,213 | 55,447,427 | CopyNumber | Variation_9663 (DGV), Variation_48827 (DGV) |
11 | 55,371,021 | 55,447,427 | CopyNumber | Variation_10359 (DGV), Variation_48834 (DGV), Variation_48835 (DGV) |
11 | 55,422,586 | 55,596,313 | CopyNumber | Variation_10360 (DGV) |
11 | 55,360,213 | 55,447,426 | CopyNumber | Variation_29606 (DGV) |
11 | 55,371,020 | 55,460,788 | CopyNumber | Variation_29910 (DGV) |
11 | 55,422,585 | 55,596,313 | CopyNumber | Variation_29911 (DGV) |
11 | 55,367,884 | 55,459,183 | CopyNumber | Variation_31823 (DGV) |
11 | 55,362,651 | 55,460,561 | CopyNumber | Variation_34978 (DGV) |
11 | 55,432,955 | 55,495,323 | Inversion | Variation_37124 (DGV) |
11 | 55,358,496 | 55,434,466 | CopyNumber | Variation_37484 (DGV) |
11 | 55,374,032 | 55,453,009 | CopyNumber | Variation_38079 (DGV) |
11 | 55,368,154 | 55,450,788 | CopyNumber | Variation_38972 (DGV) |
11 | 55,335,878 | 55,453,486 | CopyNumber | Variation_48051 (DGV) |
11 | 55,381,588 | 55,474,194 | CopyNumber | Variation_48053 (DGV) |
11 | 55,422,490 | 55,475,200 | CopyNumber | Variation_48055 (DGV) |
11 | 55,360,213 | 55,442,368 | CopyNumber | Variation_48826 (DGV) |
11 | 55,360,213 | 55,470,003 | CopyNumber | Variation_48828 (DGV) |
11 | 55,371,021 | 55,437,126 | CopyNumber | Variation_48832 (DGV) |
11 | 55,371,021 | 55,442,368 | CopyNumber | Variation_48833 (DGV) |
11 | 55,371,021 | 55,460,095 | CopyNumber | Variation_48836 (DGV) |
11 | 55,383,157 | 55,447,427 | CopyNumber | Variation_48837 (DGV), Variation_53573 (DGV) |
11 | 55,396,041 | 55,442,368 | CopyNumber | Variation_48839 (DGV) |
11 | 55,339,829 | 55,447,427 | CopyNumber | Variation_53140 (DGV) |
11 | 55,408,664 | 55,447,427 | CopyNumber | Variation_53178 (DGV) |
11 | 55,360,213 | 55,490,377 | CopyNumber | Variation_53507 (DGV) |
11 | 55,360,213 | 55,460,788 | CopyNumber | Variation_53994 (DGV) |
11 | 55,360,213 | 55,470,994 | CopyNumber | Variation_54018 (DGV) |
11 | 55,364,677 | 55,453,061 | CopyNumber | Variation_65955 (DGV) |
11 | 55,422,345 | 55,603,590 | CopyNumber | Variation_65956 (DGV) |
11 | 55,366,131 | 55,452,023 | CopyNumber | Variation_75644 (DGV) |
11 | 55,421,049 | 55,452,023 | CopyNumber | Variation_75645 (DGV) |
11 | 55,422,701 | 55,509,962 | CopyNumber | Variation_85778 (DGV) |
11 | 55,365,707 | 55,452,023 | CopyNumber | Variation_85779 (DGV) |
Deletion | 255 (Hasin) | |||
11 | 55,432,543 | 55,435,569 | Deletion | #310 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
L112V | I133T | A154T | I208M | R231W | % Freq | CORP | |
---|---|---|---|---|---|---|---|
1 | L | I | A | I | R | 71.97 | 0.044 |
2 | L | T | A | I | R | 25.73 | 0.044 |
3 | L | I | T | I | R | 1.38 | 0.044 |
4 | V | I | A | I | R | 0.31 | 0.044 |
5 | L | I | A | I | W | 0.23 | 0.037 |
6 | L | I | A | M | R | 0.15 | 0.044 |
7 | V | T | A | I | R | 0.15 | 0.044 |
8 | L | T | A | M | R | 0.08 | 0.044 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR4C6.aApr07 | exon_5UTR | chr11 | 55,658,268 | 55,658,392 | + | |
exon_5UTR | chr11 | 55,662,151 | 55,662,248 | + | ||
main_exon | 5UTR | chr11 | 55,665,125 | 55,665,167 | + | |
CDS | chr11 | 55,665,167 | 55,666,093 | + | ||
3UTR | chr11 | 55,666,093 | 55,666,686 | + |