OR4D6 Olfactory Receptor
Gene Symbol | OR4D61 (View this gene in GeneCards) |
Family | 4 |
Subfamily | D |
Pseudogene | No |
CORP pseudogene probability score | |
Aliases | OR11-250, HsOR11.13.7, ORL3421 |
External Ids | HGNC: 15175 GeneBank: AB065803, AF399569, BK004307, NM_001004708 ORDB: ORL3421 |
Build #39 labels | OR4D6 |
Chromosomal location | 11:59,456,961-59,457,902 (+) |
Cluster | 11@59a |
Synteny | CLIC#27 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR4D10 | 64.63% | 311 |
OR4D11 | 66.34% | 309 |
OR4D9 | 67.96% | 309 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR4D9D | 69% | 311 |
Mouse | Or4d6 | 88% | 314 |
Rat | Or4d6 | 88% | 314 |
Cow | OR4D9D | 68% | 311 |
Orang | OR4D6B | 94% | 309 |
Horse | OR4D6C | 84% | 314 |
Horse | OR4D6DP | 83% | 273 |
Chimp | OR4D9 | 67% | 309 |
Expression evidences
Source | Accession |
---|---|
mRNA | BC137029 |
Sequence information
Nucleotide sequence |
ATGGACCAGATCAACCACACTAATGTGAAGGAGTTTTTCTTCCTGGAACTTACACGTTCC CGAGAGCTGGAGTTTTTCTTGTTTGTGGTCTTCTTTGCTGTGTATGTAGCAACAGTCCTG GGAAATGCACTCATTGTGGTCACTATTACCTGTGAGTCCCGCCTACACACTCCTATGTAC TTTCTCCTGCGGAACAAATCAGTCCTGGACATCGTTTTTTCATCTATCACCGTCCCCAAG TTCCTGGTGGATCTTTTATCAGACAGGAAAACCATCTCCTACAATGACTGCATGGCACAG ATCTTTTTCTTCCACTTTGCTGGTGGGGCAGATATTTTTTTCCTCTCTGTGATGGCCTAT GACAGATACCTTGCAATCGCCAAGCCCCTGCACTATGTGACCATGATGAGGAAAGAGGTG TGGGTGGCCTTGGTGGTGGCTTCTTGGGTGAGTGGTGGTTTGCATTCAATCATCCAGGTA ATTCTGATGCTTCCATTCCCCTTCTGTGGCCCCAACACACTGGATGCCTTCTACTGTTAT GTGCTCCAGGTGGTAAAACTGGCCTGCACTGACACCTTTGCTTTGGAGCTTTTCATGATC TCTAACAACGGACTGGTGACCCTGCTCTGGTTCCTCCTGCTCCTGGGCTCCTACACTGTC ATTCTGGTGATGCTGAGATCCCACTCTGGGGAGGGGCGGAACAAGGCCCTCTCCACGTGC ACGTCCCACATGCTGGTGGTGACTCTTCACTTCGTGCCTTGTGTTTACATCTACTGCCGG CCCTTCATGACGCTGCCCATGGACACAACCATATCCATTAATAACACGGTCATTACCCCC ATGCTGAACCCCATCATCTATTCCCTGAGAAATCAAGAGATGAAGTCAGCCATGCAGAGG CTGCAGAGGAGACTTGGGCCTTCCGAGAGCAGAAAATGGGGG |
Conceptual translation |
MDQINHTNVKEFFFLELTRSRELEFFLFVVFFAVYVATVLGNALIVVTITCESRLHTPMY FLLRNKSVLDIVFSSITVPKFLVDLLSDRKTISYNDCMAQIFFFHFAGGADIFFLSVMAY DRYLAIAKPLHYVTMMRKEVWVALVVASWVSGGLHSIIQVILMLPFPFCGPNTLDAFYCY VLQVVKLACTDTFALELFMISNNGLVTLLWFLLLLGSYTVILVMLRSHSGEGRNKALSTC TSHMLVVTLHFVPCVYIYCRPFMTLPMDTTISINNTVITPMLNPIIYSLRNQEMKSAMQR LQRRLGPSESRKWG Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
11 | 59,224,765 | 59,224,765 | NS | A/C | D/A | rs17500380 (DbSNP) |
11 | 59,224,885 | 59,224,885 | NS | C/G | T/S | rs1453542 (DbSNP) |
11 | 59,224,464 | 59,224,464 | NS | C/G | Q/E | rs17153766 (DbSNP) |
11 | 59,224,738 | 59,224,738 | NS | C/T | S/F | rs17153770 (DbSNP) |
11 | 59,224,608 | 59,224,608 | NS | G/A | V/M | rs1453544 (DbSNP) |
11 | 59,224,720 | 59,224,720 | NS | G/A | G/D | rs1453543 (DbSNP) |
11 | 59,225,221 | 59,225,221 | NS | T/C | M/T | rs1453541 (DbSNP) |
11 | 59,457,292 | 59,457,292 | NS | A/C | D/A | 1000GP (CEU) |
11 | 59,457,247 | 59,457,247 | NS | A/G | D/G | 1000GP (CEU, CHBJPT) |
11 | 59,457,265 | 59,457,265 | NS | T/C | F/S | 1000GP (CEU, CHBJPT) |
11 | 59,457,748 | 59,457,748 | NS | T/C | M/T | 1000GP (CEU, CHBJPT) |
11 | 59,457,412 | 59,457,412 | NS | G/C | S/T | 1000GP (CEU, CHBJPT) |
11 | 59,457,135 | 59,457,135 | NS | A/G | M/V | 1000GP (CEU, CHBJPT) |
11 | 59,456,991 | 59,456,991 | NS | G/C | E/Q | 1000GP (CHBJPT) |
11 | 59,457,657 | 59,457,657 | NS | C/T | R/W | 1000GP (CHBJPT) |
11 | 100 | -100 | NS | C/A | F/L | 1000GP (YRI, YRI, YRI, YRI, YRI) |
11 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
E11Q | F13L | R21Q | M59V | R64W | S87L | D96G | F102S | D111A | S151T | M224L | V247M | M263T | V277I | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | E | F | R | M | R | S | G | F | D | S | M | V | M | V | 58.91 | 0.641 |
2 | E | F | R | V | R | S | G | F | D | T | M | V | T | V | 16.36 | 0.937 |
3 | E | F | R | M | R | S | G | S | D | S | M | V | T | V | 6.14 | 0.641 |
4 | E | F | R | M | R | S | D | F | D | S | M | V | M | V | 6.07 | 0.641 |
5 | E | F | R | M | R | S | G | F | D | T | M | V | T | V | 3.38 | 0.641 |
6 | Q | F | R | M | R | S | D | F | D | S | M | V | M | V | 2.76 | 0.641 |
7 | E | F | R | M | R | S | G | F | A | S | M | V | M | V | 2.46 | 0.687 |
8 | E | F | R | M | W | S | G | S | D | S | M | M | T | V | 0.61 | 0.766 |
9 | E | F | R | M | R | S | G | S | D | S | L | V | T | V | 0.46 | 0.641 |
10 | E | F | R | V | R | S | G | F | D | S | M | V | T | V | 0.38 | 0.937 |
11 | E | L | R | M | R | S | G | S | D | S | M | V | T | V | 0.38 | 0.641 |
12 | E | F | R | M | R | S | G | S | D | T | M | V | T | V | 0.31 | 0.641 |
13 | E | F | R | M | R | L | G | S | D | S | M | V | T | V | 0.31 | 0.641 |
14 | E | F | R | M | R | S | G | F | D | T | M | V | M | V | 0.31 | 0.641 |
15 | E | F | R | M | R | S | D | F | D | S | M | V | M | I | 0.31 | 0.641 |
16 | E | F | Q | M | R | S | G | F | D | S | M | V | M | V | 0.23 | 0.641 |
17 | E | F | R | V | R | S | G | F | D | T | M | V | M | V | 0.15 | 0.937 |
18 | E | F | R | M | R | S | G | F | D | S | M | V | T | V | 0.15 | 0.641 |
19 | E | F | R | M | R | S | G | S | D | S | M | V | M | V | 0.15 | 0.641 |
20 | Q | F | R | M | R | S | D | F | A | S | M | V | M | V | 0.08 | 0.687 |
21 | E | F | R | V | R | S | G | F | D | S | M | V | M | V | 0.08 | 0.937 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR4D6.aApr07-unspliced | main_exon | CDS | chr11 | 59,456,961 | 59,457,902 | + |
3UTR | chr11 | 59,457,902 | 59,457,905 | + |