OR4F15 Olfactory Receptor
| Gene Symbol | OR4F151 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | F |
| Pseudogene | No |
| CORP pseudogene probability score | 0.1 (functional) |
| Aliases | OR15-14, HsOR15.2.2, ORL3143 |
| External Ids | HGNC: 15078 GeneBank: AB065900, AF399573, AY284005-AY284036, BK004405, NM_001001674 ORDB: ORL3143 |
| Build #39 labels | OR4F15 |
| Chromosomal location | 15:101,818,187-101,819,122 (+) |
| Cluster | 15@102 |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4F14P | 71.7% | 311 |
| OR4F1P | 71.7% | 311 |
| OR4F2P | 71.06% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4F1 | 73% | 311 |
| Mouse | Or4f15 | 86% | 311 |
| Rat | Or4f15 | 84% | 311 |
| Cow | OR4F58B | 74% | 311 |
| Orang | OR4F15BP | 94% | 312 |
| Orang | OR4F15P | 93% | 312 |
| Horse | OR4F15CP | 85% | 311 |
| Chimp | OR4F14 | 71% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137065 |
| GNF Atlas2 | gnf1h10666_at |
Sequence information
| Nucleotide sequence |
ATGAATGGAATGAATCACTCTGTGGTATCAGAATTTGTATTCATGGGACTCACCAACTCA CGGGAGATTCAGCTTCTACTTTTTGTTTTCTCTTTGTTGTTCTACTTTGCGAGCATGATG GGAAACCTTGTCATTGTATTCACTGTAACCATGGATGCTCATCTGCACTCCCCCATGTAT TTCCTCCTGGCTAACCTCTCAATCATTGATATGGCATTTTGCTCAATTACAGCCCCTAAG ATGATTTGTGATATTTTCAAGAAGCACAAGGCCATCTCCTTTCGGGGATGTATTACTCAG ATCTTCTTTAGCCATGCTCTTGGGGGCACTGAGATGGTGCTGCTCATAGCCATGGCCTTT GACAGATACATGGCCATATGTAAACCTCTCCACTACCTGACCATCATGAGCCCAAGAATG TGTCTATACTTTTTAGCCACTTCCTCTATCATTGGCCTTATCCACTCATTGGTCCAATTA GTTTTTGTGGTAGATTTACCTTTTTGTGGTCCTAATATCTTTGACAGTTTTTACTGTGAT CTCCCTCGGCTCCTCAGACTTGCCTGTACCAACACCCAAGAACTGGAGTTCATGGTCACT GTCAATAGTGGACTCATTTCTGTGGGCTCCTTTGTCTTGCTGGTAATTTCCTACATCTTC ATTCTGTTCACTGTTTGGAAACATTCTTCTGGTGGTCTAGCCAAGGCCCTCTCTACCCTG TCAGCTCATGTCACTGTGGTCATCTTGTTCTTTGGGCCACTGATGTTTTTCTACACATGG CCTTCTCCCACATCACACCTGGATAAATATCTTGCTATTTTTGATGCATTTATTACTCCT TTTCTGAATCCAGTTATCTACACATTCAGGAACAAAGACATGAAAGTGGCAATGAGGAGA CTGTGCAGTCGTCTTGCGCATTTTACAAAGATTTTG |
| Conceptual translation |
MNGMNHSVVSEFVFMGLTNSREIQLLLFVFSLLFYFASMMGNLVIVFTVTMDAHLHSPMY FLLANLSIIDMAFCSITAPKMICDIFKKHKAISFRGCITQIFFSHALGGTEMVLLIAMAF DRYMAICKPLHYLTIMSPRMCLYFLATSSIIGLIHSLVQLVFVVDLPFCGPNIFDSFYCD LPRLLRLACTNTQELEFMVTVNSGLISVGSFVLLVISYIFILFTVWKHSSGGLAKALSTL SAHVTVVILFFGPLMFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTFRNKDMKVAMRR LCSRLAHFTKIL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 15 | 100 | -100 | NS | G/A | A/T | 1000GP (YRI) |
| 15 | 101,818,591 | 101,818,591 | NS | C/G | I/M | 1000GP (CEU) |
| 15 | 101,819,000 | 101,819,000 | NS | G/A | A/T | 1000GP (CEU) |
| 15 | 102,358,450 | 102,358,450 | NS | C/T | R/W | rs61737700 (DbSNP) |
| 15 | 102,358,523 | 102,358,523 | NS | C/T | T/I | rs61737907 (DbSNP) |
| 15 | 102,358,677 | 102,358,677 | SYN | A/C | G/G | rs61737898 (DbSNP) |
| 15 | 102,358,835 | 102,358,835 | NS | C/T | S/F | rs61737725 (DbSNP) |
| 15 | 102,358,939 | 102,358,939 | NS | C/T | L/F | rs61739201 (DbSNP) |
| 15 | 102,359,307 | 102,359,307 | SYN | A/G | A/A | rs12324219 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 49 (Hasin) | |||
| 15 | 101,991,277 | 102,393,237 | CopyNumber | Variation_34506 (DGV) |
| 15 | 102,036,377 | 102,393,237 | CopyNumber | Variation_8808 (DGV) |
| 15 | 102,271,630 | 102,431,074 | CopyNumber | Variation_3985 (DGV) |
| 15 | 102,277,237 | 102,431,074 | CopyNumber | Variation_2202 (DGV) |
| 15 | 102,305,129 | 102,393,477 | CopyNumber | Variation_8809 (DGV) |
| 15 | 102,358,290 | 102,361,325 | CopyNumber | #92 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R21Q | I45T | R95Q | Y143* | S149F | L184F | A272T | D293E | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | I | R | Y | S | L | A | D | 92.93 | 0.283 |
| 2 | R | I | R | Y | S | L | T | D | 5.53 | 0.283 |
| 3 | R | I | Q | Y | S | L | A | D | 0.46 | 0.283 |
| 4 | R | I | R | * | S | L | A | D | 0.31 | 1.200 |
| 5 | R | T | R | Y | S | L | A | D | 0.31 | 0.144 |
| 6 | R | I | R | Y | F | L | A | D | 0.23 | 0.283 |
| 7 | R | I | R | Y | S | F | T | D | 0.08 | 0.283 |
| 8 | Q | I | R | Y | S | L | A | D | 0.08 | 0.283 |
| 9 | R | I | R | Y | S | L | A | E | 0.08 | 0.283 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4F15.aApr07-unspliced | main_exon | CDS | chr15 | 101,818,187 | 101,819,122 | + |
| 3UTR | chr15 | 101,819,122 | 101,819,125 | + | ||