OR51J1 Olfactory Receptor
| Gene Symbol | OR51J11 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | J |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | HsOR11.3.62P |
| External Ids | HGNC: 14856 |
| Build #39 labels | OR51J2, OR51J1P |
| Chromosomal location | 11:5,402,597-5,403,544 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (rs1909261) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51A1P | 49.17% | 301 |
| OR51G1 | 44.69% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BE170478 |
| mRNA | AB529238 |
Sequence information
| Nucleotide sequence |
ATGAAAATTTCTAATAACTCTTTGGGGTTTTTACCTACGACTTTCATTTTGGTTGGCATC CCAGGGCTGGAGTCAGAGCACCTCTGGATATCCGTCCCCTTCTCCCTGATATACATCATC ATTTTCCTTGGGAATGGCATCATTCTTCACGTCATCAGAACAGATATTGCCCTACATCAA CCCATGTACCTCTTCCTTGCCATGTTGGCACTGGCCGAGGTTCGTGTCTCTGCATCCACC CTGCCTACAGTGTTAGGCATATTCCTTTTTGGAAATACTGAAATTAGTCTTGAAGCTTGT CTTTTTCCAGATGTTCTCCATCCATTCTTTATCCATGATGGAGCCAGCTGTGCTGCTGGC CATGTCTTTGGACCGCTTTATAGCCATCTACAGCCCACTGAGCTACACAGCTATCCTGAC ACTGCCCAGGGTCTTTGGCACAGGAGCTATTATCGTACTGAAAAGCATTATGCTCATGGC TCCGTTGCCCATTCTCTTATGGCGTCTGCCCTTCTGTGGCCACAATGCCCTCTCACATTC CTATTGTCTGCACCCCAATCTTATCTATCTTGTGGGAACATTTCTGTTAACAATATCTAT GGGATTTTCATTGTTACCTCTACTTTTGGGCTGGATTCGTTGCTGATTGTGATCTCCTAT GGGCTCATACTCCACACTGTATTGGGTATTGCCACTGGAGAAGGGAGGAAGAAGGCACTC AACACATGTGGCTCACACGTCTGTGCTGTGCTTGCTTACTATGTGCCTATGATTGGCTTG TCTATAGTGCACCGCCTTGGACATCGTGTGTCCCCTCTGCTGCAAGCCATGATGGCCAAT GCCTACCTCTTCTTCCCACCTGTTGTCAATCCTATTGTCTACAGCATTAAGACCAAGGAG ATCCATGGTGCCATTGTCCGAATGCTATTAGAGAAAAGACGCAGAGTG |
| Conceptual translation |
MKISNNSLGFLPTTFILVGIPGLESEHLWISVPFSLIYIIIFLGNGIILHVIRTDIALHQ PMYLFLAMLALAEVRVSASTLPTVLGIFLFGNTEISLEACLFPDVLHPFFIHDGASCAAG HVFGPLYSHLQPTELHSYPDTAQGLWHRSYYRTEKHYAHGSVAHSLMASALLWPQCPLTF LLSAPQSYLSCGNISVNNIYGIFIVTSTFGLDSLLIVISYGLILHTVLGIATGEGRKKAL NTCGSHVCAVLAYYVPMIGLSIVHRLGHRVSPLLQAMMANAYLFFPPVVNPIVYSIKTKE IHGAIVRMLLEKRRRV Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | A/T | N/I | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | T/A | T/T | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 5,402,638 | 5,402,638 | SYN | T/A | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,402,701 | 5,402,701 | SYN | C/T | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,402,747 | 5,402,747 | NS | G/A | V/I | 1000GP (CEU) |
| 11 | 5,402,820 | 5,402,820 | NS | G/A | R/H | 1000GP (CEU, CHBJPT) |
| 11 | 5,402,895 | 5,402,895 | NS | G/A | C/Y | 1000GP (CEU, CHBJPT) |
| 11 | 5,402,940 | 5,402,940 | NS | C/T | A/V | 1000GP (CEU, CHBJPT) |
| 11 | 5,403,002 | 5,403,002 | NS | C/T | H/Y | 1000GP (CEU, CHBJPT) |
| 11 | 5,403,200 | 5,403,200 | NS | A/G | I/V | 1000GP (CEU) |
| 11 | 5,403,274 | 5,403,274 | SYN | T/C | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,403,277 | 5,403,277 | SYN | A/G | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 5,403,302 | 5,403,302 | SYN | A/C | R/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,403,322 | 5,403,322 | SYN | A/G | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,403,364 | 5,403,364 | SYN | T/A | P/P | 1000GP (CHBJPT) |
| 11 | 5,403,471 | 5,403,471 | NS | T/C | I/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,423,868 | 5,423,868 | SYN | A/T | T/T | rs2647583 (DbSNP) |
| 11 | 5,423,931 | 5,423,931 | SYN | T/C | S/S | rs2736526 (DbSNP) |
| 11 | 5,424,041 | 5,424,040 | Ins(1) | -/C | rs34397899 (DbSNP) | |
| 11 | 5,424,050 | 5,424,050 | NS | G/A | R/H | rs1909262 (DbSNP) |
| 11 | 5,424,125 | 5,424,125 | NS | G/A | C/Y | rs1909261 (DbSNP) |
| 11 | 5,424,170 | 5,424,170 | NS | T/C | V/A | rs2647582 (DbSNP) |
| 11 | 5,424,232 | 5,424,232 | NS | T/C | Y/H | rs1909260 (DbSNP) |
| 11 | 5,424,389 | 5,424,388 | Ins(4) | -/TATC | rs72114742 (DbSNP) | |
| 11 | 5,424,397 | 5,424,396 | Ins(4) | -/ATCT | rs61459896 (DbSNP) | |
| 11 | 5,424,398 | 5,424,397 | Ins(4) | -/ATCT | rs34058308 (DbSNP) | |
| 11 | 5,424,430 | 5,424,430 | NS | A/G | I/V | rs7929412 (DbSNP) |
| 11 | 5,424,504 | 5,424,504 | SYN | C/T | T/T | rs872163 (DbSNP) |
| 11 | 5,424,507 | 5,424,507 | SYN | A/G | V/V | rs872164 (DbSNP) |
| 11 | 5,424,532 | 5,424,532 | SYN | A/C | R/R | rs872165 (DbSNP) |
| 11 | 5,424,552 | 5,424,552 | SYN | A/G | T/T | rs872166 (DbSNP) |
| 11 | 5,424,701 | 5,424,701 | NS | C/T | T/I | rs16930511 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,416,622 | 5,492,033 | CopyNumber | Variation_2901 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| N6I | V18A | V51I | A72D | R75H | C100Y | A115V | H136Y | T141S | S165F | N198S | I202V | I292T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | N | V | V | A | R | C | A | H | T | S | N | I | I | 47.08 | 1.000 |
| 2 | N | V | V | A | R | Y | V | Y | T | S | N | I | I | 17.20 | 1.000 |
| 3 | N | V | V | A | H | C | A | H | T | S | N | I | I | 14.52 | 1.000 |
| 4 | N | V | V | A | H | C | A | H | T | S | N | V | I | 9.14 | 1.000 |
| 5 | N | V | V | A | H | C | A | H | T | S | N | I | T | 7.53 | 1.000 |
| 6 | N | V | V | D | R | C | A | H | T | S | N | I | I | 2.61 | 1.000 |
| 7 | I | V | V | A | R | Y | V | Y | T | S | N | I | I | 0.77 | 1.000 |
| 8 | N | V | I | A | H | C | A | H | T | S | N | I | T | 0.31 | 1.000 |
| 9 | N | V | V | A | H | C | V | Y | T | S | N | I | I | 0.15 | 1.000 |
| 10 | N | V | I | A | R | C | A | H | T | S | N | I | I | 0.15 | 1.000 |
| 11 | N | V | V | A | H | C | A | H | T | F | N | I | I | 0.15 | 1.000 |
| 12 | N | V | V | A | R | Y | V | H | T | S | N | I | I | 0.08 | 1.000 |
| 13 | N | A | V | A | H | C | A | H | T | S | N | I | I | 0.08 | 1.000 |
| 14 | N | V | V | A | H | C | A | H | T | S | S | I | I | 0.08 | 1.000 |
| 15 | N | V | V | A | R | Y | V | Y | S | S | N | I | I | 0.08 | 1.000 |
| 16 | N | V | V | A | R | Y | A | Y | T | S | N | I | I | 0.08 | 1.000 |