OR5K2 Olfactory Receptor
Gene Symbol | OR5K21 (View this gene in GeneCards) |
Family | 5 |
Subfamily | K |
Pseudogene | No |
CORP pseudogene probability score | 0.27 (functional) |
Aliases | OR3-9, HsOR3.3.17, ORL3095 |
External Ids | HGNC: 14774 GeneBank: AB065457, BK004415, NM_001004737 ORDB: ORL3095 |
Build #39 labels | OR5K2 |
Chromosomal location | 3:98,497,681-98,498,628 (+) |
Cluster | 3@98 |
Synteny | CLIC#9 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR5K1 | 94.79% | 307 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR5K1 | 83% | 316 |
Mouse | Or5k1 | 83% | 307 |
Rat | Or5k1-ps | 83% | 307 |
Cow | OR5K1 | 83% | 316 |
Orang | OR5K1 | 93% | 307 |
Horse | OR5K1P | 83% | 289 |
Chimp | OR5K2P | 95% | 316 |
Chimp | OR5K1 | 94% | 307 |
Expression evidences
Source | Accession |
---|---|
ESTs | DA427661 |
mRNA | BC136724 |
Sequence information
Nucleotide sequence |
ATGGTTGAAGAAAATCATACCATGAAAAATGAGTTTATCCTCACAGGATTTACAGATCAC CCTGAGCTGAAGACTCTGCTGTTTGTGGTGTTCTTTGCCATCTATCTGATCACCGTGGTG GGGAATATTAGTTTGGTGGCACTGATATTTACACACTGTCGGCTTCACACACCAATGTAC ATCTTTCTGGGAAATCTGGCTCTTGTGGATTCTTGCTGTGCCTGTGCTATTACCCCCAAA ATGTTAGAGAACTTCTTTTCTGAGGGCAAAAGGATTTCCCTCTATGAATGTGCAGTACAG TTTTATTTTCTTTGCACTGTGGAAACTGCAGACTGCTTTCTTCTGGCAGCAGTGGCCTAT GACCGCTATGTGGCCATCTGCAACCCACTGCAGTACCACATCATGATGTCCAAGAAACTC TGCATTCAGATGACCACAGGCGCCTTCATAGCTGGAAATCTGCATTCCATGATTCATGTA GGGCTTGTATTTAGGTTAGTTTTCTGTGGATTGAATCACATCAACCACTTTTACTGTGAT ACTCTTCCCTTGTATAGACTCTCCTGTGTTGACCCTTTCATCAATGAACTGGTTCTATTC ATCTTCTCAGGTTCAGTTCAAGTCTTTACCATAGGTAGTGTCTTAATATCTTATCTCTAT ATTCTTCTTACTATTTTCAGAATGAAATCCAAGGAGGGAAGGGCCAAAGCCTTTTCTACT TGTGCATCCCACTTTTCATCAGTTTCATTATTCTATGGATCTATTTTTTTCCTATACATT AGACCAAATTTGCTTGAAGAAGGAGGTAATGATATACCAGCTGCTATTTTATTTACAATA GTAGTTCCCTTACTAAATCCTTTCATTTATAGTCTGAGAAACAAGGAAGTAATAAGTGTC TTAAGAAAAATTCTGCTGAAAATAAAATCTCAAGGAAGTGTGAACAAA |
Conceptual translation |
MVEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHCRLHTPMY IFLGNLALVDSCCACAITPKMLENFFSEGKRISLYECAVQFYFLCTVETADCFLLAAVAY DRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGLNHINHFYCD TLPLYRLSCVDPFINELVLFIFSGSVQVFTIGSVLISYLYILLTIFRMKSKEGRAKAFST CASHFSSVSLFYGSIFFLYIRPNLLEEGGNDIPAAILFTIVVPLLNPFIYSLRNKEVISV LRKILLKIKSQGSVNK Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
3 | 98,217,178 | 98,217,178 | nonsense SNP | A/T | */Y | rs55639376 (DbSNP) |
3 | 98,217,050 | 98,217,050 | NS | A/C | N/H | rs59427166 (DbSNP) |
3 | 98,217,368 | 98,217,368 | NS | C/G | L/V | rs61733537 (DbSNP) |
3 | 98,216,681 | 98,216,681 | NS | C/T | R/C | rs1729959 (DbSNP) |
3 | 98,217,154 | 98,217,154 | SYN | C/T | T/T | rs58947289 (DbSNP) |
3 | 100 | -100 | NS | C/A | H/N | 1000GP (YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
L115V | R122H | T146S | H176N | Y218* | % Freq | CORP | |
---|---|---|---|---|---|---|---|
1 | L | R | T | H | Y | 85.71 | 0.402 |
2 | L | R | T | H | * | 11.83 | 1.200 |
3 | L | R | T | N | Y | 1.84 | 0.510 |
4 | V | R | T | H | Y | 0.23 | 0.402 |
5 | L | H | T | H | Y | 0.23 | 0.923 |
6 | L | H | T | H | * | 0.08 | 1.200 |
7 | L | R | S | H | * | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR5K2.aApr07-unspliced | main_exon | CDS | chr3 | 98,497,681 | 98,498,628 | + |
3UTR | chr3 | 98,498,628 | 98,498,631 | + |